Table 18. Gonococcal Isolate Surveillance Project (GISP) -- Resistance of Neisseria gonorrhoeae from
selected cities to penicillin and tetracycline, 1992-1995 *
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1992 | 1993
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Penicillin Tetracycline | Penicillin Tetracycline
CLINIC Total Resistance Resistance | Total Resistance Resistance
Isolates No. % No. % | Isolates No. % No. %
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Albuquerque, NM 123 2 1.6 11 8.9 | 136 12 8.8 36 26.5
Anchorage, AK 123 8 6.5 7 5.7 | 122 7 5.7 7 5.7
Atlanta, GA 236 62 26.3 63 26.7 | 238 54 22.7 71 29.8
Baltimore, MD 240 100 41.7 98 40.8 | 240 73 30.4 61 25.4
Birmingham, AL 240 20 8.3 102 42.5 | 240 27 11.3 102 42.5
Boston, MA 192 32 16.7 58 30.2 | NR NR NR NR NR
Cincinnati, OH 239 70 29.3 64 26.8 | 236 79 33.5 90 38.1
Cleveland, OH 240 18 7.5 21 8.8 | 240 24 10.0 23 9.6
Denver, CO 240 29 12.1 19 7.9 | 240 14 5.8 19 7.9
Fort Lewis, WA 119 16 13.4 13 10.9 | 143 23 16.1 24 16.8
Honolulu, HI 79 11 13.9 20 25.3 | 82 11 13.4 14 17.1
Kansas City, MO 240 26 10.8 8 3.3 | 239 36 15.1 4 1.7
Long Beach, CA 240 44 18.3 38 15.8 | 236 33 14.0 38 16.1
Minneapolis, MN NR NR NR NR NR | 240 32 13.3 56 23.3
Nassau County, NY 217 63 29.0 86 39.6 | 223 51 22.9 66 29.6
New Orleans, LA 200 52 26.0 69 34.5 | 180 30 16.7 46 25.6
Orange County, CA 240 64 26.7 48 20.0 | 223 56 25.1 44 19.7
Philadelphia, PA 235 76 32.3 97 41.3 | 234 46 19.7 51 21.8
Phoenix, AZ 233 23 9.9 40 17.2 | 240 33 13.8 23 9.6
Portland, OR 240 25 10.4 13 5.4 | 240 44 18.3 18 7.5
San Diego, CA 214 29 13.6 44 20.6 | 224 19 8.5 42 18.8
Seattle, WA 240 45 18.8 64 26.7 | 229 43 18.8 48 21.0
San Francisco, CA 240 37 15.4 11 4.6 | 240 22 9.2 31 12.9
St Louis, MO 240 5 2.1 37 15.4 | 135 1 0.7 14 10.4
San Antonio, TX 238 42 17.6 60 25.2 | 228 39 17.1 60 26.3
West Palm Beach, FL 240 71 29.6 146 60.8 | 237 36 15.2 110 46.4
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TOTAL 5,328 970 18.2 1,237 23.2 | 5,265 845 16.0 1,098 20.9
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|
1994 | 1995
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Penicillin Tetracycline | Penicillin Tetracycline
CLINIC Total Resistance Resistance | Total Resistance Resistance
Isolates No. % No. % | Isolates No. % No. %
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Albuquerque, NM 158 19 12.0 34 21.5 | 167 5 3.0 25 15.0
Anchorage, AK 171 1 0.6 3 1.8 | 123 5 4.1 7 5.7
Atlanta, GA 229 46 20.1 86 37.6 | 227 51 22.5 124 54.6
Baltimore, MD 240 41 17.1 63 26.3 | 240 50 20.8 76 31.7
Birmingham, AL 240 37 15.4 111 46.3 | 239 53 22.2 60 25.1
Boston, MA NR NR NR NR NR | NR NR NR NR NR
Cincinnati, OH 218 39 17.9 136 62.4 | 173 23 13.3 98 56.6
Cleveland, OH 240 42 17.5 64 26.7 | 227 34 15.0 88 38.8
Denver, CO 240 32 13.3 33 13.8 | 240 14 5.8 21 8.8
Fort Lewis, WA 78 9 11.5 14 17.9 | 68 12 17.6 6 8.8
Honolulu, HI 74 23 31.1 22 29.7 | 61 18 29.5 14 23.0
Kansas City, MO 240 24 10.0 13 5.4 | 240 8 3.3 9 3.8
Long Beach, CA 214 44 20.6 34 15.9 | 217 44 20.3 46 21.2
Minneapolis, MN 240 22 9.2 25 10.4 | 240 14 5.8 13 5.4
Nassau County, NY 161 61 37.9 56 34.8 | 180 54 30.0 30 16.7
New Orleans, LA 210 37 17.6 79 37.6 | 190 25 13.2 142 74.7
Orange County, CA 201 51 25.4 18 9.0 | 144 24 16.7 36 25.0
Philadelphia, PA 228 58 25.4 67 29.4 | 232 52 22.4 32 13.8
Phoenix, AZ 228 18 7.9 18 7.9 | 240 16 6.7 24 10.0
Portland, OR 240 20 8.3 17 7.1 | 240 5 2.1 15 6.3
San Diego, CA 240 32 13.3 31 12.9 | 240 20 8.3 24 10.0
Seattle, WA 206 14 6.8 25 12.1 | 230 21 9.1 52 22.6
San Francisco, CA 240 26 10.8 36 15.0 | 240 13 5.4 45 18.8
St Louis, MO NR NR NR NR NR | 93 16 17.2 29 31.2
San Antonio, TX 221 32 14.5 55 24.9 | 154 17 11.0 84 54.5
West Palm Beach, FL 239 68 28.5 86 36.0 | 229 105 45.9 135 59.0
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TOTAL 4,996 796 15.9 1,126 22.5 | 4,874 699 14.3 1,235 25.3
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* NR = No report available
NOTE: Resistance categories include both plasmid-mediated and chromosomally mediated resistance. Penicillin and tetracycline resistance
categories are not mutually exclusive; many isolates are resistant to both antibiotics.
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