United States Cancer Statistics

• Cancer Incidence 1999 - 2021:  By year, state, metropolitan area, age group, race, ethnicity, sex, childhood cancers and cancer site classifications.
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• Cancer Mortality 1999 - 2021:  By year, state, metropolitan area, age group, race, ethnicity, sex, and cancer site classifications. See below for more information on mortality rate comparisons.
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• Cancer Mortality Incidence Rate Ratios 1999 - 2021:  By year, state, metropolitan area, race, ethnicity, sex, and cancer site classifications. See below for more information on mortality rate comparisons.
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• National Program of Cancer Registries 5 year Relative Survival:  By race, sex, age group and cancer site classifications. Current NPCR 5-year survival statistics are available at
  United States Cancer Statistics: Data Visualizations.

CDC WONDER maintains archive versions of previous releases of data on this website to allow users to replicate data requests that were conducted in the past. Please refer to the main data repositories, listed above, to access current data.

Click here to access the archived data.

The United States Cancer Statistics (USCS) are the official federal statistics on cancer incidence from registries having high-quality data and cancer mortality statistics for 50 states and the District of Columbia. USCS are produced by the Centers for Disease Control and Prevention (CDC) and the National Cancer Institute (NCI). For a list of all USCS contributors and partners, visit USCS Contributors.

Incidence data are provided by:

• The Centers for Disease Control and Prevention National Program of Cancer Registries (NPCR)
• The National Cancer Institute Surveillance, Epidemiology and End Results (SEER) program

the Centers for Disease Control and Prevention National Vital Statistics System (NVSS). Cancer mortality data for deaths after 2018 are available from NVSS.

About mortality rate comparisons:

• For consistency with the data on cancer incidence, the cancer sites in mortality data were grouped according to the revised SEER recodes dated March 1, 2018 (see SEER Cause of Death Recodes). Because NCHS uses different groupings for some sites, the death rates in this report may differ slightly from those published by NCHS.
• The population used to age-adjust the rates in this report is the 2000 U.S. standard population, which is in accordance with a 1998 recommendation of the US. Department of Health and Human Services. The 2000 U.S. standard population is based on the proportion of the 2000 population in specific age groups (younger than 1 year, 1-4 years, 5-9 years, 10-14 years, 15-19 years, . . . 85 years or older); the proportions of the 2000 population in these age groups serve as weights for calculating age-adjusted incidence and death rates. NCHS, however, uses a different set of age groups in its age adjustment of death rates, and thus the cancer death rates in this report may differ slightly from those published by NCHS.
• Deaths of persons of unknown age are not included in this data set. Death rates may differ slightly from other reports where deaths of persons of unknown age are included.