TABLE 1. Reported cases of notifiable diseases and rates per 100,000, excluding U.S. territories - - United States, 2016 column labels in same order that data fields appears in each record below: Disease Case Count Rate tab delimited data: Anthrax — — Arboviral diseases, Chikungunya virus disease 247 0.08 Arboviral diseases, Eastern equine encephalitis virus disease, Neuroinvasive 7 0.00 Arboviral diseases, Eastern equine encephalitis virus disease, Non-neuroinvasive — — Arboviral diseases, Jamestown Canyon virus disease, Neuroinvasive 7 0.00 Arboviral diseases, Jamestown Canyon virus disease, Non-neuroinvasive 8 0.00 Arboviral diseases, La Crosse virus disease, Neuroinvasive 31 0.01 Arboviral diseases, La Crosse virus disease, Non-neuroinvasive 4 0.00 Arboviral diseases, Powassan virus disease, Neuroinvasive 21 0.01 Arboviral diseases, Powassan virus disease, Non-neuroinvasive 1 0.00 Arboviral diseases, St. Louis encephalitis virus disease, Neuroinvasive 7 0.00 Arboviral diseases, St. Louis encephalitis virus disease, Non-neuroinvasive 1 0.00 Arboviral diseases, West Nile virus disease, Neuroinvasive 1,308 0.40 Arboviral diseases, West Nile virus disease, Non-neuroinvasive 841 0.26 Arboviral diseases, Western equine encephalitis virus disease, Neuroinvasive — — Arboviral diseases, Western equine encephalitis virus disease, Non-neuroinvasive — — Babesiosis, Total 1,910 0.83 Babesiosis, Confirmed 1,585 0.69 Babesiosis, Probable 325 0.14 Botulism, Total 201 0.06 Botulism, Foodborne 31 0.01 Botulism, Infant * 144 3.63 Botulism, Other (wound & unspecified) 26 0.01 Brucellosis 127 0.04 Campylobacteriosis 60,120 18.61 Chancroid 7 0.00 Chlamydia trachomatis infection 1,598,354 494.65 Cholera 15 0.00 Coccidioidomycosis † 11,829 9.01 Cryptosporidiosis, Total 13,453 4.16 Cryptosporidiosis, Confirmed 8,637 2.67 Cryptosporidiosis, Probable 4,816 1.49 Cyclosporiasis 537 0.18 Dengue virus infections, Dengue § 903 0.28 Dengue virus infections, Dengue-like illness § 40 0.01 Dengue virus infections, Severe dengue § 10 0.00 Diphtheria — — Ehrlichiosis and Anaplasmosis, Anaplasma phagocytophilum infection 4,151 1.33 Ehrlichiosis and Anaplasmosis, Ehrlichia chaffeensis infection 1,377 0.44 Ehrlichiosis and Anaplasmosis, Ehrlichia ewingii infection 22 0.01 Ehrlichiosis and Anaplasmosis, Undetermined ehrlichiosis/anaplasmosis 200 0.06 Giardiasis 16,310 6.43 Gonorrhea 468,514 144.99 Haemophilus influenzae, invasive disease, All ages, all serotypes 4,895 1.51 Haemophilus influenzae, invasive disease, Age <5 years, Serotype b ¶ 30 0.15 Haemophilus influenzae, invasive disease, Age <5 years, Non-b serotype ¶ 159 0.80 Haemophilus influenzae, invasive disease, Age <5 years, Nontypeable ¶ 196 0.98 Haemophilus influenzae, invasive disease, Age <5 years, Unknown serotype ¶ 187 0.94 Hansen's disease 78 0.03 Hantavirus infection, non-hantavirus pulmonary syndrome 6 0.00 Hantavirus pulmonary syndrome 31 0.01 Hemolytic uremic syndrome post-diarrheal 307 0.10 Hepatitis, A, acute ** 2,007 0.62 Hepatitis, B, acute ** 3,218 1.00 Hepatitis, B, perinatal infection **,†† 32 0.40 Hepatitis, C, acute ** 2,942 0.97 Human immunodeficiency virus diagnoses 34,775 10.76 Influenza-associated pediatric mortality §§ 82 0.11 Invasive pneumococcal disease, All ages 17,626 7.32 Invasive pneumococcal disease, All ages, Confirmed 17,603 7.31 Invasive pneumococcal disease, All ages, Probable 23 0.01 Invasive pneumococcal disease, Age <5 years ¶ 1,142 0.44 Invasive pneumococcal disease, Age <5 years, Confirmed ¶ 1,137 7.13 Invasive pneumococcal disease, Age <5 years, Probable ¶ 5 0.03 Legionellosis 6,141 1.90 Leptospirosis 78 0.03 Listeriosis 786 0.24 Lyme disease, Total 36,429 11.32 Lyme disease, Confirmed 26,203 8.15 Lyme disease, Probable 10,226 3.18 Malaria 1,955 0.61 Measles, Total 85 0.03 Measles, Indigenous 68 0.02 Measles, Imported 17 0.01 Meningococcal disease, All serogroups 375 0.12 Meningococcal disease, Serogroups ACWY 126 0.04 Meningococcal disease, Serogroup B 86 0.03 Meningococcal disease, Other serogroups 21 0.01 Meningococcal disease, Unknown serogroup 142 0.04 Mumps 6,369 1.97 Novel Influenza A virus infections 23 0.01 Pertussis 17,972 5.56 Plague 4 0.00 Poliomyelitis, paralytic — — Poliovirus infection, nonparalytic — — Psittacosis 12 0.00 Q fever, Total 164 0.05 Q fever, Acute 132 0.04 Q fever, Chronic 32 0.01 Rabies, Animal 4,609 1.51 Rabies, Human — — Rubella 1 0.00 Rubella, congenital syndrome * 2 0.05 Salmonellosis 53,850 16.67 Severe acute respiratory syndrome-associated coronavirus disease — — Shiga toxin-producing Escherichia coli ¶¶ 8,169 2.53 Shigellosis 21,097 6.53 Smallpox — — Spotted fever rickettsiosis, Total 4,269 1.33 Spotted fever rickettsiosis, Confirmed 154 0.05 Spotted fever rickettsiosis, Probable 4,115 1.28 Streptococcal toxic shock syndrome 283 0.14 Syphilis, Total, all stages *** 88,042 27.25 Syphilis, Congenital * 628 15.82 Syphilis, Primary and secondary 27,814 8.61 Tetanus 34 0.01 Toxic shock syndrome (other than Streptococcal) 40 0.02 Trichinellosis 26 0.01 Tuberculosis 9,272 2.87 Tularemia 230 0.07 Typhoid fever 376 0.12 Vancomycin-intermediate Staphylococcus aureus 108 0.04 Vancomycin-resistant Staphylococcus aureus — — Varicella morbidity 8,953 3.45 Varicella mortality 3 0.00 Vibriosis, Total 1,273 0.40 Vibriosis, Confirmed 1,241 0.39 Vibriosis, Probable 32 0.01 Viral hemorrhagic fevers, Crimean-Congo hemorrhagic fever virus — — Viral hemorrhagic fevers, Ebola virus — — Viral hemorrhagic fevers, Guanarito virus — — Viral hemorrhagic fevers, Junin virus — — Viral hemorrhagic fevers, Lassa virus — — Viral hemorrhagic fevers, Lujo virus — — Viral hemorrhagic fevers, Machupo virus — — Viral hemorrhagic fevers, Marburg virus — — Viral hemorrhagic fevers, Sabia virus — — Yellow fever 1 0.00 Zika virus, Zika virus disease, congenital *,††† 30 0.76 Zika virus, Zika virus disease, non-congenital 5,132 1.59 Zika virus, Zika virus infection, congenital *,††† 45 1.13 Zika virus, Zika virus infection, non-congenital 911 0.28 —: No reported cases - The reporting jurisdiction did not submit any cases to CDC. * The rate is calculated using population less than 1 year of age. † Reportable in <25 states. § Total number of reported laboratory-positive dengue cases, including all confirmed cases [by anti-dengue virus (DENV) molecular diagnostic methods or seroconversion of anti-DENV IgM] and all probable cases (by a single, positive anti-DENV IgM). ¶ The rate is calculated using population less than 5 years of age. ** Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/2015surveillance/index.htm. †† The rate is calculated using population less than 2 years of age. §§ The rate is calculated using population less than 18 years of age. ¶¶ Includes Escherichia coli O157:H7; shiga toxin-positive, serogroup non-O157; and shiga toxin positive, not serogrouped. *** Includes syphilis of all stages, including cases where stage of syphilis is not stated. ††† Data reported to ArboNET using the national surveillance case definition for congenital Zika virus disease or infection (CSTE Position Statement 16-ID-01). Additional data reported to the US Zika Pregnancy Registry for outcomes of pregnancies with laboratory evidence of possible Zika virus infection are available at https://www.cdc.gov/zika/reporting/pregnancy-outcomes.html. Cases reported to the US Zika Pregnancy Registry might not meet the national surveillance case definition for congenital Zika virus disease or infection. Notes: These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables. The list of nationally notifiable infectious diseases and conditions for 2016 and their national surveillance case definitions are available by navigating to the https://ndc.services.cdc.gov/, Surveillance Case Definitions | CDC web page, selecting "2016" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2015 by CSTE for national surveillance, that were implemented in January 2016, including updated surveillance case definitions for acute hepatitis C and chronic hepatitis C virus infections. 2016 data are reported through June 30, 2017. Publication criteria for the finalized 2016 data are available at https://wonder.cdc.gov/nndss/documents/2016_NNDSS_Publication_Criteria.pdf, /nndss/documents/2016_NNDSS_Publication_Criteria.pdf. See also https://ndc.services.cdc.gov/wp-content/uploads/Users_guide_WONDER_tables_cleared_final.pdf, Guide to Interpreting Provisional and Finalized NNDSS Data. Population estimates for incidence rates are July 1st, 2016 estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for July 1, 2011 - July 1, 2016, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2016), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states as of June 26, 2017 are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm, https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2016 mid-year estimates from the U.S. Census Bureau International Data Base accessed on July 24, 2017 at https://www.census.gov/population/international/data/idb/informationGateway.php, https://www.census.gov/population/international/data/idb/informationGateway.php. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation. Annual tables for 2016 and later years are available on https://wonder.cdc.gov/nndss/nndss_annual_tables_menu.asp, CDC WONDER. Annual summary reports from 1993-2015 are available as published in the https://www.cdc.gov/mmwr/mmwr_nd/index.html, MMWR. NNDSS annual tables since 1952 are available at https://stacks.cdc.gov/nndss, CDC Stacks (once in CDC Stacks select "Annual Reports" in the "Genre" box to the left). Suggested Citation: Centers for Disease Control and Prevention. National Notifiable Diseases Surveillance System, 2016 Annual Tables of Infectious Disease Data. Atlanta, GA. CDC Division of Health Informatics and Surveillance, 2017. Available at: https://www.cdc.gov/nndss/data-statistics/infectious-tables/index.html, https://www.cdc.gov/nndss/data-statistics/infectious-tables/index.html. https://www.cdc.gov/nndss/, National Notifiable Diseases Surveillance System Provided by https://wonder.cdc.gov, CDC WONDER