TABLE 4. Reported cases of notifiable diseases and rates per 100,000, by age, excluding U.S. territories - - United States, 2016 column labels in same order that data fields appears in each record below: Disease <1 yr, No. <1 yr, Rate 1-4 yrs, No. 1-4 yrs, Rate 5-14 yrs, No. 5-14 yrs, Rate 15-24 yrs, No. 15-24 yrs, Rate 25-39 yrs, No. 25-39 yrs, Rate 40-64 yrs, No. 40-64 yrs, Rate >=65 yrs, No. >=65 yrs, Rate Age not stated, No. Total, No. tab delimited data: Anthrax — — — — — — — — — — — — — — — — Arboviral diseases, Chikungunya virus disease — — 2 0.01 8 0.02 17 0.04 68 0.10 112 0.11 38 0.08 2 247 Arboviral diseases, Eastern equine encephalitis virus disease, Neuroinvasive — — — — — — 1 0.00 1 0.00 2 0.00 3 0.01 — 7 Arboviral diseases, Eastern equine encephalitis virus disease, Non-neuroinvasive — — — — — — — — — — — — — — — — Arboviral diseases, Jamestown Canyon virus disease, Neuroinvasive — — — — — — — — 2 0.00 3 0.00 2 0.00 — 7 Arboviral diseases, Jamestown Canyon virus disease, Non-neuroinvasive — — — — — — — — 1 0.00 3 0.00 4 0.01 — 8 Arboviral diseases, La Crosse virus disease, Neuroinvasive — — 6 0.04 19 0.05 — — 3 0.00 1 0.00 2 0.00 — 31 Arboviral diseases, La Crosse virus disease, Non-neuroinvasive — — 2 0.01 — — 1 0.00 1 0.00 — — — — — 4 Arboviral diseases, Powassan virus disease, Neuroinvasive 1 0.03 — — — — — — — — 9 0.01 11 0.02 — 21 Arboviral diseases, Powassan virus disease, Non-neuroinvasive — — — — — — — — — — 1 0.00 — — — 1 Arboviral diseases, St. Louis encephalitis virus disease, Neuroinvasive — — — — — — — — — — 3 0.00 4 0.01 — 7 Arboviral diseases, St. Louis encephalitis virus disease, Non-neuroinvasive — — — — — — — — — — 1 0.00 — — — 1 Arboviral diseases, West Nile virus disease, Neuroinvasive — — 4 0.03 19 0.05 45 0.10 145 0.22 581 0.56 514 1.04 — 1,308 Arboviral diseases, West Nile virus disease, Non-neuroinvasive — — 2 0.01 16 0.04 47 0.11 155 0.24 453 0.44 168 0.34 — 841 Arboviral diseases, Western equine encephalitis virus disease, Neuroinvasive — — — — — — — — — — — — — — — — Arboviral diseases, Western equine encephalitis virus disease, Non-neuroinvasive — — — — — — — — — — — — — — — — Babesiosis, Total — — 8 0.07 37 0.13 41 0.13 158 0.34 794 1.07 865 2.54 7 1,910 Babesiosis, Confirmed — — 5 0.04 27 0.09 28 0.09 126 0.27 620 0.84 772 2.27 7 1,585 Babesiosis, Probable — — 3 0.03 10 0.03 13 0.04 32 0.07 174 0.24 93 0.27 — 325 Botulism, Total 140 3.53 1 0.01 — — 3 0.01 23 0.04 21 0.02 9 0.02 4 201 Botulism, Foodborne — — 1 0.01 — — 3 0.01 13 0.02 8 0.01 6 0.01 — 31 Botulism, Infant * 140 3.53 — — — — — — — — — — — — 4 144 Botulism, Other (wound & unspecified) — — — — — — — — 10 0.02 13 0.01 3 0.01 — 26 Brucellosis — — 2 0.01 10 0.02 3 0.01 29 0.04 59 0.06 23 0.05 1 127 Campylobacteriosis 1,762 44.38 5,703 35.74 4,897 11.93 6,809 15.65 10,835 16.55 19,081 18.36 10,922 22.18 111 60,120 Chancroid — — — — — — 2 0.00 4 0.01 1 0.00 — — — 7 Chlamydia trachomatis infection 482 12.14 114 0.71 10,759 26.21 1,008,403 2,317.58 497,907 760.73 74,185 71.37 1,772 3.60 4,732 1,598,354 Cholera — — — — — — 2 0.00 3 0.00 7 0.01 3 0.01 — 15 Coccidioidomycosis † 7 0.43 53 0.81 491 2.91 1,097 6.15 2,320 8.69 4,948 11.81 2,898 14.69 15 11,829 Cryptosporidiosis, Total 200 5.04 1,842 11.54 2,212 5.39 1,862 4.28 3,254 4.97 2,797 2.69 1,225 2.49 61 13,453 Cryptosporidiosis, Confirmed 131 3.30 1,259 7.89 1,503 3.66 1,205 2.77 2,054 3.14 1,790 1.72 664 1.35 31 8,637 Cryptosporidiosis, Probable 69 1.74 583 3.65 709 1.73 657 1.51 1,200 1.83 1,007 0.97 561 1.14 30 4,816 Cyclosporiasis — — 5 0.03 10 0.03 38 0.10 124 0.21 277 0.29 77 0.17 6 537 Dengue virus infections, Dengue § 1 0.03 6 0.04 39 0.10 134 0.31 275 0.42 362 0.35 86 0.17 — 903 Dengue virus infections, Dengue-like illness § — — 1 0.01 1 0.00 7 0.02 14 0.02 10 0.01 3 0.01 4 40 Dengue virus infections, Severe dengue § — — — — 1 0.00 1 0.00 1 0.00 6 0.01 1 0.00 — 10 Diphtheria — — — — — — — — — — — — — — — — Ehrlichiosis and Anaplasmosis, Anaplasma phagocytophilum infection 1 0.03 18 0.12 107 0.27 147 0.35 361 0.57 1,914 1.91 1,596 3.35 7 4,151 Ehrlichiosis and Anaplasmosis, Ehrlichia chaffeensis infection 1 0.03 6 0.04 46 0.12 87 0.21 153 0.24 610 0.61 466 0.98 8 1,377 Ehrlichiosis and Anaplasmosis, Ehrlichia ewingii infection — — — — — — — — 2 0.00 9 0.01 11 0.02 — 22 Ehrlichiosis and Anaplasmosis, Undetermined ehrlichiosis/anaplasmosis — — 3 0.02 15 0.04 15 0.04 36 0.06 76 0.08 54 0.11 1 200 Giardiasis 104 3.40 1,607 13.06 1,911 6.04 1,880 5.54 3,461 6.76 5,297 6.46 1,991 5.03 59 16,310 Gonorrhea 95 2.39 92 0.58 2,534 6.17 218,302 501.72 192,987 294.86 51,384 49.43 1,599 3.25 1,521 468,514 Haemophilus influenzae, invasive disease, All ages, all serotypes 351 8.84 221 1.38 128 0.31 120 0.28 315 0.48 1,209 1.16 2,546 5.17 5 4,895 Haemophilus influenzae, invasive disease, Age <5 years, Serotype b ¶ 19 0.48 11 0.07 — — — — — — — — — — — 30 Haemophilus influenzae, invasive disease, Age <5 years, Non-b serotype ¶ 78 1.96 81 0.51 — — — — — — — — — — — 159 Haemophilus influenzae, invasive disease, Age <5 years, Nontypeable ¶ 137 3.45 59 0.37 — — — — — — — — — — — 196 Haemophilus influenzae, invasive disease, Age <5 years, Unknown serotype ¶ 117 2.95 70 0.44 — — — — — — — — — — — 187 Hansen's disease — — — — 3 0.01 4 0.01 7 0.01 29 0.03 18 0.04 17 78 Hantavirus infection, non-hantavirus pulmonary syndrome — — — — 1 0.00 1 0.00 2 0.00 2 0.00 — — — 6 Hantavirus pulmonary syndrome — — — — 2 0.00 4 0.01 7 0.01 12 0.01 6 0.01 — 31 Hemolytic uremic syndrome post-diarrheal 9 0.23 143 0.92 100 0.25 13 0.03 10 0.02 11 0.01 19 0.04 2 307 Hepatitis, A, acute ** 1 0.03 18 0.11 59 0.14 265 0.61 618 0.94 738 0.71 301 0.61 7 2,007 Hepatitis, B, acute ** 1 0.03 — — 4 0.01 107 0.25 1,192 1.84 1,705 1.65 198 0.40 11 3,218 Hepatitis, B, perinatal infection **,†† 17 0.43 15 0.38 — — — — — — — — — — — 32 Hepatitis, C, acute ** 7 0.19 3 0.02 — — 531 1.30 1,528 2.47 784 0.80 68 0.15 21 2,942 Human immunodeficiency virus diagnoses 39 0.98 15 0.09 67 0.16 7,243 16.65 15,630 23.88 11,052 10.63 729 1.48 — 34,775 Influenza-associated pediatric mortality §§ 8 0.20 26 0.16 39 0.10 9 0.07 — — — — — — — 82 Invasive pneumococcal disease, All ages 395 13.42 717 6.05 464 1.52 315 0.97 1,425 2.96 7,305 9.40 6,972 18.68 33 17,626 Invasive pneumococcal disease, All ages, Confirmed 393 13.35 715 6.04 464 1.52 315 0.97 1,425 2.96 7,299 9.39 6,959 18.64 33 17,603 Invasive pneumococcal disease, All ages, Probable 2 0.07 2 0.02 — — — — — — 6 0.01 13 0.03 — 23 Invasive pneumococcal disease, Age <5 years ¶ 408 12.86 734 5.75 — — — — — — — — — — — 1,142 Invasive pneumococcal disease, Age <5 years, Confirmed ¶ 406 12.80 731 5.72 — — — — — — — — — — — 1,137 Invasive pneumococcal disease, Age <5 years, Probable ¶ 2 0.06 3 0.02 — — — — — — — — — — — 5 Legionellosis 3 0.08 2 0.01 4 0.01 61 0.14 398 0.61 2,927 2.82 2,742 5.57 4 6,141 Leptospirosis — — — — 3 0.01 11 0.03 17 0.03 36 0.05 11 0.03 — 78 Listeriosis 34 0.86 1 0.01 5 0.01 20 0.05 61 0.09 183 0.18 480 0.97 2 786 Lyme disease, Total 21 0.53 1,283 8.08 5,776 14.13 3,495 8.07 4,822 7.40 12,970 12.53 7,360 15.02 702 36,429 Lyme disease, Confirmed 20 0.51 1,074 6.76 4,472 10.94 2,343 5.41 3,311 5.08 9,355 9.04 5,045 10.30 583 26,203 Lyme disease, Probable 1 0.03 209 1.32 1,304 3.19 1,152 2.66 1,511 2.32 3,615 3.49 2,315 4.72 119 10,226 Malaria 8 0.20 91 0.57 194 0.47 258 0.59 568 0.87 702 0.68 132 0.27 2 1,955 Measles, Total 5 0.13 9 0.06 14 0.03 16 0.04 26 0.04 15 0.01 — — — 85 Measles, Indigenous 4 0.10 7 0.04 8 0.02 15 0.03 21 0.03 13 0.01 — — — 68 Measles, Imported 1 0.03 2 0.01 6 0.01 1 0.00 5 0.01 2 0.00 — — — 17 Meningococcal disease, All serogroups 35 0.88 33 0.21 21 0.05 80 0.18 64 0.10 80 0.08 62 0.13 — 375 Meningococcal disease, Serogroups ACWY 5 0.13 16 0.10 6 0.01 14 0.03 16 0.02 39 0.04 30 0.06 — 126 Meningococcal disease, Serogroup B 18 0.45 10 0.06 6 0.01 25 0.06 11 0.02 8 0.01 8 0.02 — 86 Meningococcal disease, Other serogroups 1 0.03 2 0.01 1 0.00 6 0.01 5 0.01 4 0.00 2 0.00 — 21 Meningococcal disease, Unknown serogroup 11 0.28 5 0.03 8 0.02 35 0.08 32 0.05 29 0.03 22 0.04 — 142 Mumps 16 0.40 192 1.20 1,623 3.95 2,716 6.24 1,125 1.72 626 0.60 62 0.13 9 6,369 Novel Influenza A virus infections 1 0.03 6 0.04 9 0.02 2 0.00 — — 4 0.00 — — 1 23 Pertussis 2,020 50.88 2,435 15.26 5,833 14.21 3,998 9.19 1,094 1.67 1,905 1.83 657 1.33 30 17,972 Plague — — — — — — 2 0.00 — — — — 2 0.00 — 4 Poliomyelitis, paralytic — — — — — — — — — — — — — — — — Poliovirus infection, nonparalytic — — — — — — — — — — — — — — — — Psittacosis — — — — — — 2 0.01 3 0.01 5 0.01 2 0.00 — 12 Q fever, Total — — 1 0.01 2 0.00 6 0.01 25 0.04 89 0.09 41 0.08 — 164 Q fever, Acute — — 1 0.01 2 0.00 5 0.01 21 0.03 72 0.07 31 0.06 — 132 Q fever, Chronic — — — — — — 1 0.00 4 0.01 17 0.02 10 0.02 — 32 Rabies, Human — — — — — — — — — — — — — — — — Rubella — — — — — — — — 1 0.00 — — — — — 1 Rubella, congenital syndrome * 2 0.05 — — — — — — — — — — — — — 2 Salmonellosis 5,126 129.11 7,321 45.88 5,724 13.94 4,989 11.47 7,687 11.74 13,917 13.39 8,562 17.39 524 53,850 Severe acute respiratory syndrome-associated coronavirus disease — — — — — — — — — — — — — — — — Shiga toxin-producing Escherichia coli ¶¶ 340 8.56 1,782 11.17 1,400 3.41 1,320 3.03 1,275 1.95 1,159 1.12 806 1.64 87 8,169 Shigellosis 289 7.28 5,181 32.47 6,035 14.70 1,642 3.77 3,722 5.69 3,144 3.02 984 2.00 100 21,097 Smallpox — — — — — — — — — — — — — — — — Spotted fever rickettsiosis, Total 2 0.05 45 0.28 186 0.46 353 0.82 823 1.27 1,924 1.86 931 1.90 5 4,269 Spotted fever rickettsiosis, Confirmed — — 2 0.01 14 0.03 13 0.03 23 0.04 67 0.06 35 0.07 — 154 Spotted fever rickettsiosis, Probable 2 0.05 43 0.27 172 0.42 340 0.79 800 1.23 1,857 1.80 896 1.83 5 4,115 Streptococcal toxic shock syndrome 1 0.04 4 0.04 18 0.07 9 0.03 43 0.10 123 0.18 85 0.26 — 283 Syphilis, Total, all stages *** 634 15.97 4 0.03 42 0.10 17,544 40.32 41,556 63.49 26,306 25.31 1,867 3.79 89 88,042 Syphilis, Congenital * 628 15.82 — — — — — — — — — — — — — 628 Syphilis, Primary and secondary — — 2 0.01 17 0.04 6,470 14.87 13,498 20.62 7,511 7.23 279 0.57 37 27,814 Tetanus — — — — 5 0.01 2 0.00 9 0.01 6 0.01 3 0.01 9 34 Toxic shock syndrome (other than Streptococcal) — — — — 15 0.05 17 0.06 3 0.01 5 0.01 — — — 40 Trichinellosis — — — — 2 0.01 2 0.00 4 0.01 14 0.01 4 0.01 — 26 Tuberculosis 48 1.21 176 1.10 163 0.40 938 2.16 2,206 3.37 3,470 3.34 2,264 4.60 7 9,272 Tularemia 1 0.03 14 0.09 19 0.05 17 0.04 29 0.04 99 0.10 51 0.10 — 230 Typhoid fever 2 0.05 32 0.20 79 0.19 78 0.18 111 0.17 60 0.06 7 0.01 7 376 Vancomycin-intermediate Staphylococcus aureus 1 0.03 1 0.01 2 0.01 4 0.01 15 0.03 48 0.06 37 0.10 — 108 Vancomycin-resistant Staphylococcus aureus — — — — — — — — — — — — — — — — Varicella morbidity 768 23.90 1,927 14.95 3,228 9.75 912 2.60 822 1.55 577 0.69 112 0.29 607 8,953 Varicella mortality U U U U U U U U U U U U U U U U Vibriosis, Total 3 0.08 25 0.16 121 0.30 93 0.22 194 0.30 495 0.48 335 0.69 7 1,273 Vibriosis, Confirmed 2 0.05 23 0.15 120 0.30 93 0.22 184 0.29 491 0.48 325 0.67 3 1,241 Vibriosis, Probable 1 0.03 2 0.01 1 0.00 — — 10 0.02 4 0.00 10 0.02 4 32 Viral hemorrhagic fevers, Crimean-Congo hemorrhagic fever virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Ebola virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Guanarito virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Junin virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Lassa virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Lujo virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Machupo virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Marburg virus — — — — — — — — — — — — — — — — Viral hemorrhagic fevers, Sabia virus — — — — — — — — — — — — — — — — Yellow fever — — — — — — — — — — — — 1 0.00 — 1 Zika virus, Zika virus disease, congenital *,††† 25 0.63 — — — — — — — — — — — — 5 30 Zika virus, Zika virus disease, non-congenital 3 0.08 22 0.14 180 0.44 764 1.76 1,810 2.77 2,077 2.00 272 0.55 4 5,132 Zika virus, Zika virus infection, congenital *,††† 29 0.73 — — — — — — — — — — — — 16 45 Zika virus, Zika virus infection, non-congenital 1 0.03 — — 6 0.01 295 0.68 545 0.83 51 0.05 12 0.02 1 911 —: No reported cases - The reporting jurisdiction did not submit any cases to CDC. U: Unavailable - The data are unavailable. * The rate is calculated using population less than 1 year of age. † Reportable in <25 states. § Total number of reported laboratory-positive dengue cases, including all confirmed cases [by anti-dengue virus (DENV) molecular diagnostic methods or seroconversion of anti-DENV IgM] and all probable cases (by a single, positive anti-DENV IgM). ¶ The rate is calculated using population less than 5 years of age. ** Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/2015surveillance/index.htm. †† The rate is calculated using population less than 2 years of age. §§ The rate is calculated using population less than 18 years of age. ¶¶ Includes Escherichia coli O157:H7; shiga toxin-positive, serogroup non-O157; and shiga toxin positive, not serogrouped. *** Includes syphilis of all stages, including cases where stage of syphilis is not stated. ††† Data reported to ArboNET using the national surveillance case definition for congenital Zika virus disease or infection (CSTE Position Statement 16-ID-01). Additional data reported to the US Zika Pregnancy Registry for outcomes of pregnancies with laboratory evidence of possible Zika virus infection are available at https://www.cdc.gov/zika/reporting/pregnancy-outcomes.html. Cases reported to the US Zika Pregnancy Registry might not meet the national surveillance case definition for congenital Zika virus disease or infection. Notes: These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables. The list of nationally notifiable infectious diseases and conditions for 2016 and their national surveillance case definitions are available by navigating to the https://ndc.services.cdc.gov/, Surveillance Case Definitions | CDC web page, selecting "2016" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2015 by CSTE for national surveillance, that were implemented in January 2016, including updated surveillance case definitions for acute hepatitis C and chronic hepatitis C virus infections. 2016 data are reported through June 30, 2017. Publication criteria for the finalized 2016 data are available at https://wonder.cdc.gov/nndss/documents/2016_NNDSS_Publication_Criteria.pdf, /nndss/documents/2016_NNDSS_Publication_Criteria.pdf. See also https://ndc.services.cdc.gov/wp-content/uploads/Users_guide_WONDER_tables_cleared_final.pdf, Guide to Interpreting Provisional and Finalized NNDSS Data. Population estimates for incidence rates are July 1st, 2016 estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for July 1, 2011 - July 1, 2016, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2016), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states as of June 26, 2017 are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm, https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2016 mid-year estimates from the U.S. Census Bureau International Data Base accessed on July 24, 2017 at https://www.census.gov/population/international/data/idb/informationGateway.php, https://www.census.gov/population/international/data/idb/informationGateway.php. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation. Annual tables for 2016 and later years are available on https://wonder.cdc.gov/nndss/nndss_annual_tables_menu.asp, CDC WONDER. Annual summary reports from 1993-2015 are available as published in the https://www.cdc.gov/mmwr/mmwr_nd/index.html, MMWR. NNDSS annual tables since 1952 are available at https://stacks.cdc.gov/nndss, CDC Stacks (once in CDC Stacks select "Annual Reports" in the "Genre" box to the left). Suggested Citation: Centers for Disease Control and Prevention. National Notifiable Diseases Surveillance System, 2016 Annual Tables of Infectious Disease Data. Atlanta, GA. CDC Division of Health Informatics and Surveillance, 2017. Available at: https://www.cdc.gov/nndss/data-statistics/infectious-tables/index.html, https://www.cdc.gov/nndss/data-statistics/infectious-tables/index.html. https://www.cdc.gov/nndss/, National Notifiable Diseases Surveillance System Provided by https://wonder.cdc.gov, CDC WONDER