Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 5. Reported cases of notifiable diseases and rates per 100,000, by sex, excluding U.S. territories - - United States, 2017
Disease Female Male Sex not stated Total
No. Rate No. Rate No. No.
Anthrax — — — — — —
Arboviral diseases
Chikungunya virus disease 80 0.05 76 0.05 — 156
Eastern equine encephalitis virus disease
Neuroinvasive 3 0.00 2 0.00 — 5
Non-neuroinvasive — — — — — —
Jamestown Canyon virus disease
Neuroinvasive 25 0.02 33 0.02 — 58
Non-neuroinvasive 4 0.00 13 0.01 — 17
La Crosse virus disease
Neuroinvasive 29 0.02 34 0.02 — 63
Non-neuroinvasive — — — — — —
Powassan virus disease
Neuroinvasive 5 0.00 28 0.02 — 33
Non-neuroinvasive 1 0.00 — — — 1
St. Louis encephalitis virus disease
Neuroinvasive 2 0.00 4 0.00 — 6
Non-neuroinvasive 1 0.00 4 0.00 — 5
West Nile virus disease
Neuroinvasive 515 0.31 910 0.57 — 1,425
Non-neuroinvasive 281 0.17 391 0.24 — 672
Western equine encephalitis virus disease
Neuroinvasive — — — — — —
Non-neuroinvasive — — — — — —
Babesiosis
Total 827 0.65 1,540 1.24 1 2,368
Confirmed 674 0.53 1,320 1.06 — 1,994
Probable 153 0.12 220 0.18 1 374
Botulism
Total 83 0.05 94 0.06 — 177
Foodborne 8 0.00 11 0.01 — 19
Infant * 69 3.59 68 3.37 — 137
Other (wound & unspecified) 6 0.00 15 0.01 — 21
Brucellosis 59 0.04 81 0.05 — 140
Campylobacteriosis 31,857 19.27 35,549 22.16 131 67,537
Chancroid 3 0.00 4 0.00 — 7
Chlamydia trachomatis infection 1,127,651 682.14 577,644 360.11 3,274 1,708,569
Cholera 3 0.00 7 0.00 — 10
Coccidioidomycosis † 5,919 8.92 8,423 12.96 22 14,364
Cryptosporidiosis
Total 6,031 3.65 5,366 3.35 17 11,414
Confirmed 4,220 2.55 3,808 2.37 15 8,043
Probable 1,811 1.10 1,558 0.97 2 3,371
Cyclosporiasis 666 0.44 522 0.36 6 1,194
Dengue virus infections §
Dengue 212 0.13 225 0.14 — 437
Dengue-like illness 3 0.00 5 0.00 — 8
Severe dengue 4 0.00 5 0.00 — 9
Diphtheria — — — — — —
Ehrlichiosis and Anaplasmosis
Anaplasma phagocytophilum infection 2,190 1.37 3,564 2.31 8 5,762
Ehrlichia chaffeensis infection 651 0.41 988 0.64 3 1,642
Ehrlichia ewingii infection 13 0.01 32 0.02 — 45
Undetermined ehrlichiosis/anaplasmosis 123 0.08 146 0.10 — 269
Giardiasis 5,792 4.46 9,354 7.43 47 15,193
Gonorrhea 232,587 140.70 322,169 200.84 852 555,608
Haemophilus influenzae, invasive disease
All ages, all serotypes 3,082 1.86 2,443 1.52 23 5,548
Age <5 years 
Serotype b 17 0.17 16 0.16 — 33
Non-b serotype 81 0.83 108 1.06 — 189
Nontypeable 89 0.91 111 1.09 — 200
Unknown serotype 91 0.93 110 1.08 2 203
Hansen's disease 27 0.02 50 0.03 17 94
Hantavirus infection, non-hantavirus pulmonary syndrome 1 0.00 1 0.00 — 2
Hantavirus pulmonary syndrome 14 0.01 19 0.01 — 33
Hemolytic uremic syndrome post-diarrheal 173 0.11 165 0.11 — 338
Hepatitis **
A, acute 1,149 0.70 2,208 1.38 8 3,365
B, acute 1,301 0.79 2,095 1.31 13 3,409
B, perinatal infection †† 13 0.34 18 0.45 — 31
C, acute 1,824 1.16 2,381 1.56 20 4,225
Confirmed 1,428 0.91 1,775 1.16 10 3,213
Probable 396 0.25 606 0.40 10 1,012
Human immunodeficiency virus diagnoses 6,428 3.89 27,510 17.15 — 33,938
Influenza-associated pediatric mortality §§ 70 0.19 56 0.15 — 126
Invasive pneumococcal disease ¶¶
All ages 9,573 7.76 10,109 8.47 98 19,780
Confirmed 9,499 7.70 10,024 8.40 97 19,620
Probable 74 0.06 85 0.07 1 160
Age <5 years  528 0.40 700 0.55 6 1,234
Confirmed 522 6.69 692 8.48 6 1,220
Probable 6 0.08 8 0.10 — 14
Legionellosis 2,865 1.73 4,589 2.86 4 7,458
Leptospirosis 18 0.01 54 0.04 — 72
Listeriosis 482 0.29 401 0.25 4 887
Lyme disease
Total 17,710 10.76 24,392 15.27 641 42,743
Confirmed 12,152 7.38 16,920 10.60 441 29,513
Probable 5,558 3.38 7,472 4.68 200 13,230
Malaria 756 0.46 1,296 0.81 4 2,056
Measles
Total 52 0.03 66 0.04 2 120
Indigenous 40 0.02 57 0.04 2 99
Imported 12 0.01 9 0.01 — 21
Meningococcal disease
All serogroups 168 0.10 184 0.11 1 353
Serogroups ACWY 54 0.03 53 0.03 — 107
Serogroup B 44 0.03 46 0.03 — 90
Other serogroups 11 0.01 14 0.01 — 25
Unknown serogroup 59 0.04 71 0.04 1 131
Mumps 2,766 1.67 3,336 2.08 7 6,109
Novel Influenza A virus infections 34 0.02 32 0.02 — 66
Pertussis 10,348 6.26 8,589 5.35 38 18,975
Plague 2 0.00 3 0.00 — 5
Poliomyelitis, paralytic — — — — — —
Poliovirus infection, nonparalytic — — — — — —
Psittacosis 4 0.00 1 0.00 — 5
Q fever
Total 51 0.03 142 0.09 — 193
Acute 35 0.02 118 0.07 — 153
Chronic 16 0.01 24 0.02 — 40
Rabies
Human 2 0.00 — — — 2
Rubella 4 0.00 3 0.00 — 7
Rubella, congenital syndrome * 2 0.10 3 0.15 — 5
Salmonellosis 28,850 17.45 25,195 15.71 240 54,285
Severe acute respiratory syndrome-associated coronavirus disease — — — — — —
Shiga toxin-producing Escherichia coli *** 4,527 2.74 4,127 2.57 18 8,672
Shigellosis 6,628 4.01 8,232 5.13 52 14,912
Smallpox — — — — — —
Spotted fever rickettsiosis
Total 2,289 1.39 3,956 2.48 3 6,248
Confirmed 64 0.04 112 0.07 — 176
Probable 2,225 1.35 3,844 2.41 3 6,072
Streptococcal toxic shock syndrome 167 0.16 205 0.20 — 372
Syphilis
Total, all stages 18,146 10.98 82,314 51.32 1,107 101,567
Congenital * — — — — 918 918
Primary and secondary 3,722 2.25 26,885 16.76 37 30,644
Tetanus 17 0.01 16 0.01 — 33
Toxic shock syndrome (other than Streptococcal) 20 0.02 9 0.01 1 30
Trichinellosis 5 0.00 10 0.01 — 15
Tuberculosis 3,515 2.13 5,584 3.48 6 9,105
Tularemia 94 0.06 145 0.09 — 239
Typhoid fever 191 0.12 227 0.14 1 419
Vancomycin-intermediate Staphylococcus aureus 43 0.03 65 0.05 1 109
Vancomycin-resistant Staphylococcus aureus — — 3 0.00 — 3
Varicella morbidity 4,281 3.17 4,446 3.39 48 8,775
Varicella mortality U U U U U U
Vibriosis
Total 812 0.50 1,266 0.80 7 2,085
Confirmed 525 0.32 965 0.61 7 1,497
Probable 287 0.18 301 0.19 — 588
Viral hemorrhagic fevers
Crimean-Congo hemorrhagic fever virus — — — — — —
Ebola virus — — — — — —
Guanarito virus — — — — — —
Junin virus — — — — — —
Lassa virus — — — — — —
Lujo virus — — — — — —
Machupo virus — — — — — —
Marburg virus — — — — — —
Sabia virus — — — — — —
Yellow fever — — — — — —
Zika virus
Zika virus disease, congenital *,††† 7 0.36 15 0.74 — 22
Zika virus disease, non-congenital 324 0.20 173 0.11 — 497
Zika virus infection, congenital *,††† 8 0.42 9 0.45 — 17
Zika virus infection, non-congenital 599 0.36 42 0.03 — 641
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • U: Unavailable — The data are unavailable.
  • * The rate is calculated using population less than 1 year of age.
  • † Reportable in <25 states.
  • § Total number of reported laboratory-positive dengue cases, including all confirmed cases [by anti-dengue virus (DENV) molecular diagnostic methods or seroconversion of anti-DENV IgM] and all probable cases (by a single, positive anti-DENV IgM).
  • ¶ The rate is calculated using population less than 5 years of age.
  • ** Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/2016surveillance/index.htm.
  • †† The rate is calculated using population less than 2 years of age.
  • §§ The rate is calculated using population less than 18 years of age.
  • ¶¶ Includes drug resistant and susceptible cases of Invasive Pneumococcal Disease. This condition was previously named Streptococcus pneumoniae invasive disease and cases were reported to CDC using different event codes to specify whether the cases were drug resistant or in a defined age group, such as <5 years.
  • *** Includes Escherichia coli O157:H7 and Shiga toxin-positive Escherichia coli (including O157, non-O157, and not serogrouped).
  • ††† Data reported to ArboNET using the national surveillance case definition for congenital Zika virus disease or infection (CSTE Position Statement 16-ID-01). Additional data reported to the US Zika Pregnancy Registry for outcomes of pregnancies with laboratory evidence of possible Zika virus infection are available at https://www.cdc.gov/pregnancy/zika/data/pregnancy-outcomes.html. Cases reported to the US Zika Pregnancy Registry might not meet the national surveillance case definition for congenital Zika virus disease or infection.
Notes:
  • These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables.
  • The list of nationally notifiable infectious diseases and conditions for 2018 and their national surveillance case definitions are available by navigating to the Surveillance Case Definitions | CDC web page, selecting "2017" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2016 by CSTE for national surveillance, that were implemented in January 2017, including updated surveillance case definitions for salmonellosis, shigellosis, vibrioisis, perinatal hepatitis B virus infection, invasive pneumococcal disease, Lyme disease, and tularemia reported through August 7, 2018. Publication criteria for the finalized 2017 data are available at https://wonder.cdc.gov/nndss/documents/2017_NNDSS_Publication_Criteria.pdf. See also Guide to Interpreting Provisional and Finalized NNDSS Data.
  • Population estimates for incidence rates are July 1st, 2017 estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for April 1, 2010 - July 1, 2017, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2017), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states released June 27, 2018 are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2017 mid-year estimates from the U.S. Census Bureau International Data Base, accessed on October 2, 2018 at https://www.census.gov/data-tools/demo/idb/informationGateway.php. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation.
  • Annual tables for 2016 and later years are available on CDC WONDER.
  • Annual summary reports from 1993-2015 are available as published in the MMWR.
  • NNDSS annual tables since 1952 are available at CDC Stacks (once in CDC Stacks select "Annual Reports" in the "Genre" box to the left).
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