Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 2n. Annual reported cases of notifiable diseases, by region and reporting area - - United States and U.S. Territories, 2018
Reporting Area Syphilis Tetanus Toxic shock syndrome (other than Streptococcal) Trichinellosis Tuberculosis Tularemia
Total, all stages * Congenital Primary and secondary
United States 115,045 1,306 35,063 23 33 1 9,025 229
New England 2,166 3 888 — — — 302 5
Connecticut 264 2 91 — N — 51 —
Maine 147 — 74 — — — 14 —
Massachusetts 1,305 — 552 — — — 200 5
New Hampshire 137 1 64 — — — 12 —
Rhode Island 284 — 96 — — — 20 —
Vermont 29 — 11 — — — 5 —
Middle Atlantic 14,374 50 4,021 1 6 — 1,253 2
New Jersey 1,777 13 570 — — — 291 1
New York (excluding New York City) 1,792 9 630 — 2 — 191 —
New York City 8,391 19 2,024 — 4 — 559 —
Pennsylvania 2,414 9 797 1 — — 212 1
East North Central 9,564 64 3,316 8 9 1 770 12
Illinois 4,471 29 1,408 1 2 — 319 6
Indiana 985 1 367 1 2 — 116 2
Michigan 1,691 13 649 2 4 — 108 2
Ohio 1,908 20 740 2 1 — 178 1
Wisconsin 509 1 152 2 — 1 49 1
West North Central 3,989 39 1,537 1 9 — 382 57
Iowa 286 3 86 — N N 49 1
Kansas 495 8 152 — 3 — 28 19
Minnesota 918 10 292 1 3 — 172 2
Missouri 1,913 17 806 — 2 — 81 17
Nebraska 219 — 119 — 1 — 27 6
North Dakota 84 — 41 — — — 13 3
South Dakota 74 1 41 — — — 12 9
South Atlantic 25,418 204 7,782 5 2 — 1,622 8
Delaware 129 — 30 — — — 22 —
District of Columbia 763 — 279 — — — 36 —
Florida 10,700 108 2,880 1 N — 591 2
Georgia 4,928 31 1,607 — — N 272 —
Maryland 2,536 29 737 — N — 208 —
North Carolina 2,987 17 1,098 3 1 — 196 3
South Carolina 1,152 9 384 — 1 — 86 —
Virginia 2,038 9 702 — N — 205 2
West Virginia 185 1 65 1 — — 6 1
East South Central 5,345 31 1,860 3 1 — 375 11
Alabama 1,285 7 477 — N — 91 —
Kentucky 881 9 366 1 — — 65 7
Mississippi 1,454 3 464 — N — 80 —
Tennessee 1,725 12 553 2 1 — 139 4
West South Central 17,818 450 4,026 1 1 — 1,386 99
Arkansas 964 25 288 — 1 — 78 55
Louisiana 2,747 46 669 — — — 105 —
Oklahoma 1,138 12 531 — N — 74 44
Texas 12,969 367 2,538 1 N — 1,129 —
Mountain 7,848 111 2,653 2 5 — 391 19
Arizona 3,249 61 1,047 — 1 — 178 —
Colorado 1,084 7 337 1 4 — 64 6
Idaho 134 1 46 — — — 15 3
Montana 104 — 45 — — — 5 4
Nevada 2,000 31 682 — — — 69 2
New Mexico 812 10 304 — — — 41 1
Utah 423 1 169 — — — 18 —
Wyoming 42 — 23 1 — — 1 3
Pacific 28,523 354 8,980 2 — — 2,544 16
Alaska 113 1 55 — N — 63 —
California 25,256 332 7,607 — — — 2,092 4
Hawaii 210 4 92 — N — 120 —
Oregon 1,032 10 424 1 N — 81 8
Washington 1,912 7 802 1 N — 188 4
Territories 1,120 8 384 — — — 146 —
American Samoa — — — — N N 1 —
Commonwealth of Northern Mariana Islands 2 — 1 — — — 47 —
Guam 30 — 18 — — — 70 —
Puerto Rico 1,088 8 365 — N N 28 —
U.S. Virgin Islands — — — — — — — —
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
  • U: Unavailable — The data are unavailable.
  • * Includes the following categories: primary; secondary; early non-primary non-secondary (includes cases previously reported as early latent); and unknown duration or late (includes cases previously reported as late latent syphilis and cases previously reported as late syphilis with clinical manifestations).
Notes:
  1. These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables.
  2. The list of nationally notifiable infectious diseases and conditions for 2018 and their national surveillance case definitions are available by navigating to the Surveillance Case Definitions | CDC web page, selecting "2018" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2017 by CSTE for national surveillance, that were implemented in January 2018, including updated surveillance case definitions for anthrax, shiga toxin-producing Escherichia coli, and syphilis. Perinatal hepatitis c virus infection became a new nationally notifiable condition in 2018. While Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE) was added to the list of nationally notifiable diseases in 2018, reporting jurisdictions could not submit data for this condition since Office of Management and Budget Paperwork Reduction Act approval was pending during 2018. Publication criteria for the finalized 2018 data are available at https://wonder.cdc.gov/nndss/documents/2018_NNDSS _Publication_Criteria_07122019_updated_09230219.pdf. See also Guide to Interpreting Provisional and Finalized NNDSS Data.
  3. Annual tables for 2016 and later years are available on CDC WONDER.
  4. Annual summary reports from 1993-2015 are available as published in the MMWR.
  5. NNDSS annual tables since 1952 are available at CDC Stacks (once in CDC Stacks select "Annual Reports" in the "Genre" box to the left).
  6. For most conditions, national incidence rates are calculated as the number of reported cases for each infectious disease or condition divided by the U.S. resident population for the specified demographic population or the total U.S. resident population, multiplied by 100,000. When a nationally notifiable infectious condition is associated with a specific age restriction, the same restriction was applied to the population in the denominator of the incidence rate calculation. In addition, population data from reporting jurisdictions in which the disease or condition was not reportable or not available were excluded from the denominator of the incidence rate calculations.

    Population estimates for incidence rates are July 1st, 2018 estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for April 1, 2010 - July 1, 2018, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2018), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states released June 25, 2019 are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2018 mid-year estimates from the U.S. Census Bureau International Data Base, accessed on June 26, 2019 at https://www.census.gov/data-tools/demo/idb/informationGateway.php. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation.

    Age restrictions in the numerator and denominator are applied for the following childhood conditions:

    • Zika virus disease, congenital (age restriction in numerator and denominator is <1 year)
    • Zika virus infection, congenital (age restriction in numerator and denominator is <1 year)
    • Haemophilus influenzae, invasive disease <5 years (age restriction in numerator and denominator is <5 years)
    • Invasive pneumococcal disease <5 years (age restriction in numerator and denominator is <5 years)
    • Influenza associated pediatric mortality (age restriction in numerator and denominator is <18 years)
    • Infant botulism (age restriction in numerator and denominator is <1 year)
    • Congenital rubella syndrome (age restriction in numerator and denominator is <1 year)
    • Perinatal Hepatitis B infection (age restriction in numerator is ≤24 months, denominator is <24 months)
    • Perinatal Hepatitis C infection (age restriction in numerator is ≤36 months, denominator is <36 months)

    Data for congenital syphilis are aggregated by the infant's year of birth. The rate for congenital syphilis is based upon the number of reported cases per 100,000 live births, using natality data for 2018 (National Center for Health Statistics Natality 2018, as compiled from data provided by the Vital Statistics Cooperative Program). The mother's race and ethnicity are used for race- and ethnicity-specific rates of congenital syphilis cases. Congenital syphilis data are published in Syphilis Statistics in the Sexually Transmitted Diseases (STD) surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) and in the historical archives of the STD surveillance report (https://www.cdc.gov/std/stats/archive.htm). The STD surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) updates congenital syphilis cases and rates over time.

  7. Surveillance data reported by other CDC programs might vary from data reported in these tables because of differences in 1) the date used to aggregate the data, 2) the timing of reports, 3) the source of the data, 4) surveillance case definitions, and 5) policies regarding case jurisdiction (i.e., which jurisdiction should submit the case notification to CDC).
Suggested Citation: Acknowledgement:
  • CDC acknowledges the Local, State, and Territorial Health Departments that collected the data from a range of case ascertainment sources (e.g., health-care providers, hospitals, laboratories) and reported these data to CDC's National Notifiable Diseases Surveillance System.