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Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 3. Annual reported cases of notifiable diseases, by month*, excluding U.S. Territories - - United States, 2018
Disease Jan. Feb. Mar. Apr. May June July Aug. Sept. Oct. Nov. Dec. Unknown Total
Anthrax 1 1
Arboviral diseases
Chikungunya virus disease 7 4 4 11 9 11 18 17 13 9 4 10 117
Eastern equine encephalitis virus disease
Neuroinvasive 2 2 1 1 6
Non-neuroinvasive
Jamestown Canyon virus disease
Neuroinvasive 1 2 2 5 4 6 5 25
Non-neuroinvasive 1 3 5 1 4 1 1 16
La Crosse virus disease
Neuroinvasive 3 17 24 21 14 3 1 83
Non-neuroinvasive 1 2 3
Powassan virus disease
Neuroinvasive 1 1 2 5 6 1 2 2 1 21
Non-neuroinvasive
St. Louis encephalitis virus disease
Neuroinvasive 1 1 2 1 5
Non-neuroinvasive 2 1 3
West Nile virus disease
Neuroinvasive 2 2 2 3 4 146 546 710 160 58 24 1,657
Non-neuroinvasive 1 1 3 9 146 354 406 48 12 9 989
Western equine encephalitis virus disease
Neuroinvasive
Non-neuroinvasive
Babesiosis
Total 10 17 16 15 39 385 682 412 222 104 75 183 2,160
Confirmed 8 10 11 9 26 327 601 372 184 91 63 159 1,861
Probable 2 7 5 6 13 58 81 40 38 13 12 24 299
Botulism
Total 17 14 19 18 14 21 13 16 22 20 21 30 225
Foodborne 1 2 3 3 1 1 1 5 17
Infant 14 11 17 11 10 12 6 12 11 15 17 21 157
Other (wound & unspecified) 2 3 2 5 4 6 4 4 10 4 3 4 51
Brucellosis 3 5 14 17 15 14 10 12 14 6 14 14 138
Campylobacteriosis 3,244 3,321 4,836 4,699 5,407 9,038 7,607 6,864 7,124 5,220 4,796 8,044 70,200
Chancroid 1 1 1 3
Chlamydia trachomatis infection 126,499 134,590 169,317 136,608 135,445 163,507 131,200 144,821 176,966 141,520 128,844 169,351 1,758,668
Cholera 2 1 1 1 4 2 1 2 14
Coccidioidomycosis  1,880 1,304 1,389 995 1,131 1,356 1,197 1,160 1,354 1,211 1,127 1,507 15,611
Cryptosporidiosis
Total 539 533 780 779 795 1,202 1,452 1,768 1,774 1,023 781 1,107 12,533
Confirmed 347 328 508 512 521 854 1,100 1,316 1,351 765 566 812 8,980
Probable 192 205 272 267 274 348 352 452 423 258 215 295 3,553
Cyclosporiasis 4 7 15 22 148 1,147 1,639 325 113 26 20 53 3,519
Dengue virus infections §
Dengue 19 9 5 13 14 20 49 56 47 50 70 72 424
Dengue-like illness 2 1 2 3 2 6 8 3 6 8 41
Severe dengue 1 2 2 2 2 9
Diphtheria 1 1
Ehrlichiosis and Anaplasmosis
Anaplasma phagocytophilum infection 15 30 40 93 414 1,202 762 424 378 246 227 177 4,008
Ehrlichia chaffeensis infection 7 15 22 37 136 464 376 227 211 88 47 169 1,799
Ehrlichia ewingii infection 1 8 13 3 4 2 2 33
Undetermined ehrlichiosis/anaplasmosis 3 1 8 8 23 78 54 31 30 20 16 11 283
Giardiasis 929 1,021 1,338 994 1,039 1,338 1,334 1,638 1,974 1,266 1,005 1,672 15,548
Gonorrhea 42,421 41,729 51,973 42,765 43,558 55,240 45,523 48,239 60,385 48,206 44,278 59,088 583,405
Haemophilus influenzae, invasive disease
All ages, all serotypes 555 478 582 441 425 556 365 299 428 351 369 724 5,573
Age <5 years
Serotype b 3 3 1 5 5 8 1 2 2 2 1 5 38
Non-b serotype 13 25 21 17 13 14 13 5 15 10 14 31 191
Nontypeable 18 29 27 14 18 23 7 13 17 14 15 27 222
Unknown serotype 14 11 17 18 14 14 10 9 13 8 13 34 175
Hansen's disease 4 7 8 5 7 10 4 19 6 11 4 5 90
Hantavirus infection, non-hantavirus pulmonary syndrome 2 2
Hantavirus pulmonary syndrome 1 1 2 1 1 2 2 1 3 1 1 2 18
Hemolytic uremic syndrome post-diarrheal 9 3 20 31 34 45 59 34 56 24 39 22 376
Hepatitis 
A, acute 249 295 411 486 524 1,101 1,011 1,228 1,702 1,538 1,565 2,364 12,474
B, acute 206 247 291 260 219 316 264 256 339 261 249 414 3,322
B, perinatal infection 3 3 2 2 2 3 3 2 3 23
C, acute 293 326 418 357 432 428 336 373 544 355 296 610 4,768
Confirmed 250 277 347 290 332 344 266 269 333 255 213 445 3,621
Probable 43 49 71 67 100 84 70 104 211 100 83 165 1,147
C, perinatal infection 15 20 24 20 25 22 8 9 22 13 12 24 214
Human immunodeficiency virus diagnoses 3,151 2,894 3,225 3,004 3,224 3,173 3,176 3,264 2,734 2,848 1,788 517 1 32,999
Influenza-associated pediatric mortality 36 53 24 18 9 4 2 1 4 1 7 159
Invasive pneumococcal disease **
All ages 2,820 2,386 2,417 1,892 1,565 1,340 741 621 993 1,059 1,263 2,760 19,857
Confirmed 2,789 2,364 2,383 1,874 1,549 1,325 725 611 981 1,048 1,242 2,728 19,619
Probable 31 22 34 18 16 15 16 10 12 11 21 32 238
Age <5 years 101 122 132 91 85 92 36 37 78 84 91 167 1,116
Confirmed 98 118 126 90 84 89 32 35 77 82 87 160 1,078
Probable 3 4 6 1 1 3 4 2 1 2 4 7 38
Legionellosis 313 280 392 256 387 1,233 1,046 1,311 1,664 1,384 738 929 9,933
Leptospirosis 6 4 6 2 4 10 7 7 24 6 4 11 91
Listeriosis 31 39 57 48 44 86 88 119 108 76 72 96 864
Lyme disease
Total 996 1,112 1,306 1,282 2,018 6,171 6,782 4,549 3,330 2,270 1,792 2,058 33,666
Confirmed 647 706 802 808 1,275 4,424 5,023 3,296 2,329 1,574 1,273 1,401 23,558
Probable 349 406 504 474 743 1,747 1,759 1,253 1,001 696 519 657 10,108
Malaria 99 89 78 117 135 223 152 197 240 145 98 175 1,748
Measles
Total 10 5 28 29 13 13 13 12 9 43 72 128 375
Indigenous 5 2 21 19 6 4 7 8 5 28 70 121 296
Imported 5 3 7 10 7 9 6 4 4 15 2 7 79
Meningococcal disease
All serogroups 37 38 38 21 26 21 21 14 21 20 23 47 327
Serogroups ACWY 11 10 11 10 7 8 7 3 5 9 10 9 100
Serogroup B 9 12 9 5 7 5 8 5 6 6 6 3 81
Other serogroups 3 4 5 1 4 1 3 2 23
Unknown serogroup 14 12 13 6 11 8 6 6 6 4 4 33 123
Mumps 266 298 352 245 286 137 100 127 128 135 124 317 2,515
Novel Influenza A virus infections 1 13 14
Paratyphoid fever †† 13 10 12 12 9 12 13 11 17 7 8 9 133
Pertussis 1,013 988 1,219 1,100 1,294 1,509 1,233 1,114 1,322 1,085 1,280 2,452 15,609
Plague 1 1
Poliomyelitis, paralytic
Poliovirus infection, nonparalytic
Psittacosis 3 1 2 1 9 3 1 2 22
Q fever
Total 10 9 32 26 26 20 16 20 18 7 11 20 215
Acute 8 6 30 22 20 17 13 18 16 7 9 12 178
Chronic 2 3 2 4 6 3 3 2 2 2 8 37
Rabies
Animal 213 225 405 445 483 418 543 728 566 466 277 215 4,984
Human 1 1 1 3
Rubella 1 1 2 4
Rubella, congenital syndrome
Salmonellosis (excluding paratyphoid fever and typhoid fever) §§ 2,112 2,489 3,227 3,014 3,783 6,710 6,813 7,345 9,233 6,091 4,264 5,918 60,999
Severe acute respiratory syndrome-associated coronavirus disease
Shiga toxin-producing Escherichia coli (STEC) 553 574 975 1,172 1,184 2,164 1,887 1,867 1,744 1,219 917 1,740 15,996
Shigellosis 855 796 1,279 1,013 1,123 1,588 1,503 1,643 1,719 1,365 1,403 2,046 16,333
Smallpox
Spotted fever rickettsiosis
Total 53 57 175 239 516 1,338 929 742 766 346 175 208 5,544
Confirmed 1 2 6 9 12 33 19 13 16 3 2 8 124
Probable 52 55 169 230 504 1,305 910 729 750 343 173 200 5,420
Streptococcal toxic shock syndrome 50 45 55 31 26 34 29 18 14 12 24 33 371
Syphilis
Total, all stages ¶¶ 8,162 8,731 11,132 9,134 8,884 10,756 8,664 9,113 11,591 9,302 8,532 11,044 115,045
Congenital 107 84 106 95 89 105 115 112 136 128 116 113 1,306
Primary and secondary 2,413 2,581 3,354 2,750 2,685 3,326 2,767 2,736 3,700 2,850 2,634 3,267 35,063
Tetanus 3 4 2 1 5 1 2 3 2 23
Toxic shock syndrome (other than Streptococcal) 6 2 2 3 4 2 2 2 3 4 3 33
Trichinellosis 1 1
Tuberculosis 506 587 770 766 770 817 717 853 636 789 737 1,077 9,025
Tularemia 2 3 7 22 42 54 32 15 25 5 22 229
Typhoid fever 28 23 34 36 35 24 28 43 61 23 8 58 401
Vancomycin-intermediate Staphylococcus aureus 5 8 13 3 8 10 7 2 6 5 7 11 85
Vancomycin-resistant Staphylococcus aureus
Varicella morbidity 512 577 791 685 761 769 493 506 824 639 646 998 8,201
Varicella mortality 1 2 1 1 1 6
Vibriosis
Total 63 84 128 131 118 324 400 507 389 234 166 420 2,964
Confirmed 29 38 63 56 68 229 275 355 240 137 84 248 1,822
Probable 34 46 65 75 50 95 125 152 149 97 82 172 1,142
Viral hemorrhagic fevers
Crimean-Congo hemorrhagic fever virus
Ebola virus
Guanarito virus
Junin virus
Lassa virus
Lujo virus
Machupo virus
Marburg virus
Sabia virus
Yellow fever
Zika virus
Zika virus disease, congenital *** 1 1 2
Zika virus disease, non-congenital 12 7 7 6 2 3 11 10 4 8 4 5 79
Zika virus infection, congenital *** 2 2 1 1 1 1 8
Zika virus infection, non-congenital 18 28 21 31 19 14 14 14 23 19 11 33 245
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • * Month is defined using MMWR week (http://wwwn.cdc.gov/nndss/document/MMWR_Week_overview.pdf). MMWR week calendars can be found at http://wwwn.cdc.gov/nndss/script/downloads.aspx.
  • † Reportable in <25 states.
  • § Counts include confirmed and probable dengue cases.
  • ¶ Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/SurveillanceRpts.htm.
  • ** Counts include drug resistant and susceptible cases of Invasive Pneumococcal Disease. This condition was previously named Streptococcus pneumoniae invasive disease and cases were reported to CDC using different event codes to specify whether the cases were drug resistant or in a defined age group, such as <5 years.
  • †† Prior to 2018, cases of paratyphoid fever were considered salmonellosis.
  • §§ Prior to 2018, cases of paratyphoid fever were included as salmonellosis, but beginning in 2018 they are being published as paratyphoid fever.
  • ¶¶ Includes the following categories: primary; secondary; early non-primary non-secondary (includes cases previously reported as early latent); and unknown duration or late (includes cases previously reported as late latent syphilis and cases previously reported as late syphilis with clinical manifestations).
  • *** Data reported to ArboNET using the national surveillance case definition for congenital Zika virus infection (CSTE Position Statement 16-ID-01).

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