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Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 6. Annual reported cases of notifiable diseases and rates per 100,000, by race*,†, excluding U.S. Territories - - United States, 2018
Disease American Indian or
Alaska Native
Asian or Pacific
Islander
Black White Other Race Race not stated Total
No. Rate No. Rate No. Rate No. Rate No. No. No.
Anthrax S S S S S S S S S S 1
Arboviral diseases
Chikungunya virus disease 33 0.15 6 0.01 31 0.01 7 40 117
Eastern equine encephalitis virus disease
Neuroinvasive S S S S S S S S S S 6
Non-neuroinvasive
Jamestown Canyon virus disease
Neuroinvasive 1 0.00 17 0.01 4 3 25
Non-neuroinvasive S S S S S S S S S S 16
La Crosse virus disease
Neuroinvasive 3 0.06 1 0.00 72 0.03 1 6 83
Non-neuroinvasive S S S S S S S S S S 3
Powassan virus disease
Neuroinvasive S S S S S S S S S S 21
Non-neuroinvasive
St. Louis encephalitis virus disease
Neuroinvasive S S S S S S S S S S 5
Non-neuroinvasive S S S S S S S S S S 3
West Nile virus disease
Neuroinvasive 18 0.38 21 0.10 125 0.27 1,132 0.44 76 285 1,657
Non-neuroinvasive 21 0.44 9 0.04 29 0.06 661 0.26 33 236 989
Western equine encephalitis virus disease
Neuroinvasive
Non-neuroinvasive
Babesiosis
Total 6 0.18 57 0.31 38 0.10 1,294 0.61 97 668 2,160
Confirmed 5 0.15 49 0.27 35 0.10 1,123 0.53 92 557 1,861
Probable 1 0.03 8 0.04 3 0.01 171 0.08 5 111 299
Botulism
Total 4 0.08 8 0.04 7 0.02 153 0.06 17 36 225
Foodborne S S S S S S S S S S 17
Infant 2 2.68 6 2.51 3 0.45 108 3.76 5 33 157
Other (wound & unspecified) 3 0.01 35 0.01 10 3 51
Brucellosis 3 0.06 6 0.03 12 0.03 76 0.03 20 21 138
Campylobacteriosis 523 11.04 1,988 9.20 3,631 7.85 43,146 16.95 6,820 14,092 70,200
Chancroid S S S S S S S S S S 3
Chlamydia trachomatis infection 20,089 423.88 29,331 135.78 487,967 1,054.77 543,911 213.66 126,988 550,382 1,758,668
Cholera S S S S S S S S S S 14
Coccidioidomycosis § 192 7.78 478 4.68 575 3.98 4,828 4.48 3,732 5,806 15,611
Cryptosporidiosis
Total 68 1.43 192 0.89 941 2.03 8,837 3.47 665 1,830 12,533
Confirmed 48 1.01 134 0.62 704 1.52 6,158 2.42 505 1,431 8,980
Probable 20 0.42 58 0.27 237 0.51 2,679 1.05 160 399 3,553
Cyclosporiasis 13 0.32 67 0.33 136 0.33 2,468 1.09 300 535 3,519
Dengue virus infections 
Dengue 1 0.02 70 0.32 18 0.04 175 0.07 37 123 424
Dengue-like illness 8 0.04 3 0.01 19 0.01 2 9 41
Severe dengue S S S S S S S S S S 9
Diphtheria S S S S S S S S S S 1
Ehrlichiosis and Anaplasmosis
Anaplasma phagocytophilum infection 21 0.50 28 0.14 15 0.03 2,684 1.09 145 1,115 4,008
Ehrlichia chaffeensis infection 6 0.14 9 0.04 52 0.11 1,161 0.47 54 517 1,799
Ehrlichia ewingii infection 1 0.00 24 0.01 2 6 33
Undetermined ehrlichiosis/anaplasmosis 1 0.02 2 0.01 2 0.00 206 0.09 26 46 283
Giardiasis 94 2.57 374 2.03 979 2.80 7,863 3.94 1,916 4,322 15,548
Gonorrhea 8,427 177.81 7,851 36.35 224,280 484.80 178,560 70.14 35,842 128,445 583,405
Haemophilus influenzae, invasive disease
All ages, all serotypes 91 1.92 90 0.42 731 1.58 3,511 1.38 176 974 5,573
Age <5 years
Serotype b 3 0.79 3 0.09 25 0.17 1 6 38
Non-b serotype 22 5.79 2 0.16 44 1.30 89 0.60 6 28 191
Nontypeable 9 2.37 8 0.62 33 0.97 131 0.89 11 30 222
Unknown serotype 5 1.32 11 0.86 23 0.68 84 0.57 21 31 175
Hansen's disease 1 0.03 13 0.07 4 0.01 40 0.02 5 27 90
Hantavirus infection, non-hantavirus pulmonary syndrome S S S S S S S S S S 2
Hantavirus pulmonary syndrome S S S S S S S S S S 18
Hemolytic uremic syndrome post-diarrheal 4 0.09 11 0.05 11 0.02 282 0.11 35 33 376
Hepatitis **
A, acute 15 0.32 108 0.50 506 1.09 8,793 3.45 794 2,258 12,474
B, acute 26 0.55 56 0.26 409 0.89 2,201 0.87 142 488 3,322
B, perinatal infection S S S S S S S S S S 23
C, acute 94 2.27 32 0.15 277 0.63 3,428 1.42 265 672 4,768
Confirmed 84 2.03 28 0.13 241 0.55 2,535 1.05 220 513 3,621
Probable 10 0.24 4 0.02 36 0.08 893 0.37 45 159 1,147
C, perinatal infection 1 0.02 1 0.01 3 0.01 102 0.04 16 91 214
Human immunodeficiency virus diagnoses 165 3.48 776 3.59 14,354 31.03 8,822 3.47 8,882 32,999
Influenza-associated pediatric mortality 4 0.29 6 0.13 27 0.22 102 0.19 3 17 159
Invasive pneumococcal disease ††
All ages 311 10.53 302 2.42 3,035 7.98 11,900 6.25 694 3,615 19,857
Confirmed 306 10.36 299 2.39 3,001 7.89 11,759 6.18 678 3,576 19,619
Probable 5 0.17 3 0.02 34 0.09 141 0.07 16 39 238
Age <5 years 21 0.60 37 0.28 236 0.58 571 0.28 39 212 1,116
Confirmed 20 6.99 37 4.44 230 7.73 548 4.66 37 206 1,078
Probable 1 0.35 6 0.20 23 0.20 2 6 38
Legionellosis 49 1.03 117 0.54 2,251 4.87 6,037 2.37 495 984 9,933
Leptospirosis 6 0.03 45 0.02 18 22 91
Listeriosis 3 0.06 52 0.24 94 0.20 553 0.22 55 107 864
Lyme disease
Total 80 1.69 222 1.07 248 0.54 17,507 6.89 761 14,848 33,666
Confirmed 53 1.12 147 0.71 161 0.35 12,063 4.75 578 10,556 23,558
Probable 27 0.57 75 0.36 87 0.19 5,444 2.14 183 4,292 10,108
Malaria 2 0.04 79 0.37 1,156 2.50 185 0.07 95 231 1,748
Measles
Total 15 0.07 5 0.01 230 0.09 7 118 375
Indigenous 1 0.00 1 0.00 189 0.07 4 101 296
Imported 14 0.06 4 0.01 41 0.02 3 17 79
Meningococcal disease
All serogroups 3 0.06 12 0.06 40 0.09 214 0.08 16 42 327
Serogroups ACWY 1 0.02 4 0.02 14 0.03 66 0.03 4 11 100
Serogroup B 2 0.04 6 0.03 4 0.01 58 0.02 3 8 81
Other serogroups 7 0.02 14 0.01 2 23
Unknown serogroup 2 0.01 15 0.03 76 0.03 9 21 123
Mumps 36 0.76 388 1.80 215 0.46 1,077 0.42 94 705 2,515
Novel Influenza A virus infections S S S S S S S S S S 14
Paratyphoid fever §§ 4 0.08 44 0.20 4 0.01 42 0.02 16 23 133
Pertussis 288 6.08 325 1.50 650 1.41 10,778 4.23 608 2,960 15,609
Plague S S S S S S S S S S 1
Poliomyelitis, paralytic
Poliovirus infection, nonparalytic
Psittacosis S S S S S S S S S S 22
Q fever
Total 3 0.06 8 0.04 5 0.01 140 0.06 31 28 215
Acute 3 0.06 8 0.04 4 0.01 117 0.05 27 19 178
Chronic 1 0.00 23 0.01 4 9 37
Rabies
Human S S S S S S S S S S 3
Rubella S S S S S S S S S S 4
Rubella, congenital syndrome
Salmonellosis (excluding paratyphoid fever and typhoid fever) ¶¶ 462 9.75 1,981 9.17 5,311 11.48 38,325 15.06 4,677 10,243 60,999
Severe acute respiratory syndrome-associated coronavirus disease
Shiga toxin-producing Escherichia coli (STEC) 153 3.23 389 1.80 781 1.69 10,989 4.32 1,339 2,345 15,996
Shigellosis 104 2.19 560 2.59 2,774 6.00 8,638 3.39 1,733 2,524 16,333
Smallpox
Spotted fever rickettsiosis
Total 40 0.87 19 0.09 139 0.30 3,641 1.44 156 1,549 5,544
Confirmed 10 0.22 1 0.00 3 0.01 73 0.03 9 28 124
Probable 30 0.65 18 0.09 136 0.29 3,568 1.41 147 1,521 5,420
Streptococcal toxic shock syndrome 1 0.04 17 0.15 49 0.15 247 0.15 15 42 371
Syphilis
Total, all stages *** 1,224 25.83 3,053 14.13 38,051 82.25 53,657 21.08 9,353 9,707 115,045
Congenital 32 75.93 27 9.60 518 81.76 649 22.89 29 51 1,306
Primary and secondary 418 8.82 971 4.50 11,490 24.84 16,974 6.67 2,600 2,610 35,063
Tetanus S S S S S S S S S S 23
Toxic shock syndrome (other than Streptococcal) 1 0.01 1 0.00 20 0.01 1 10 33
Trichinellosis S S S S S S S S S S 1
Tuberculosis 115 2.43 3,213 14.87 1,845 3.99 3,560 1.40 171 121 9,025
Tularemia 11 0.23 2 0.01 1 0.00 153 0.06 11 51 229
Typhoid fever 3 0.06 193 0.89 28 0.06 64 0.03 61 52 401
Vancomycin-intermediate Staphylococcus aureus 9 0.02 47 0.02 1 28 85
Vancomycin-resistant Staphylococcus aureus
Varicella morbidity 83 2.31 422 2.28 526 1.38 4,526 2.18 398 2,246 8,201
Varicella mortality U U U U U U U U U U U
Vibriosis
Total 15 0.32 114 0.53 199 0.43 1,984 0.79 192 460 2,964
Confirmed 10 0.21 77 0.36 104 0.23 1,261 0.50 119 251 1,822
Probable 5 0.11 37 0.17 95 0.21 723 0.29 73 209 1,142
Viral hemorrhagic fevers
Crimean-Congo hemorrhagic fever virus
Ebola virus
Guanarito virus
Junin virus
Lassa virus
Lujo virus
Machupo virus
Marburg virus
Sabia virus
Yellow fever
Zika virus
Zika virus disease, congenital ††† S S S S S S S S S S 2
Zika virus disease, non-congenital 3 0.01 26 0.01 10 40 79
Zika virus infection, congenital ††† S S S S S S S S S S 8
Zika virus infection, non-congenital 1 0.02 10 0.05 41 0.09 104 0.04 14 75 245
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • U: Unavailable — The data are unavailable.
  • S: Suppressed
  • * Conditions with <25 cases reported in the year were not broken down by race.
  • † Race data were collected using current Office of Management and Budget (OMB) standards for race/ethnicity data and were mapped to bridged race categories.
  • § Reportable in <25 states.
  • ¶ Counts include confirmed and probable dengue cases.
  • ** Chronic hepatitis B and C data are not included in NNDSS tables but reported case counts are included in the annual Summary of Viral Hepatitis, published online by CDC's Division of Viral Hepatitis, available at https://www.cdc.gov/hepatitis/statistics/SurveillanceRpts.htm.
  • †† Counts include drug resistant and susceptible cases of Invasive Pneumococcal Disease. This condition was previously named Streptococcus pneumoniae invasive disease and cases were reported to CDC using different event codes to specify whether the cases were drug resistant or in a defined age group, such as <5 years.
  • §§ Prior to 2018, cases of paratyphoid fever were considered salmonellosis.
  • ¶¶ Prior to 2018, cases of paratyphoid fever were included as salmonellosis, but beginning in 2018 they are being published as paratyphoid fever.
  • *** Includes the following categories: primary; secondary; early non-primary non-secondary (includes cases previously reported as early latent); and unknown duration or late (includes cases previously reported as late latent syphilis and cases previously reported as late syphilis with clinical manifestations).
  • ††† Data reported to ArboNET using the national surveillance case definition for congenital Zika virus infection (CSTE Position Statement 16-ID-01).

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