Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 2j. Annual reported cases of notifiable diseases, by region and reporting area, United States and U.S. Territories, excluding Non-U.S. Residents*, 2019†
Data from some jurisdictions may be incomplete due to the coronavirus disease 2019 (COVID-19) pandemic. Please see Note #9 at the bottom of the table.
Reporting Area Listeriosis § Lyme disease
Total Confirmed Probable Total Confirmed Probable
U.S. Residents, excluding U.S. Territories 928 880 48 34,945 23,453 11,492
New England 54 54 — 7,152 4,769 2,383
Connecticut 13 13 — 1,233 795 438
Maine 5 5 — 2,167 1,629 538
Massachusetts 28 28 — 7 6 1
New Hampshire 5 5 — 1,710 1,106 604
Rhode Island 2 2 — 971 527 444
Vermont 1 1 — 1,064 706 358
Middle Atlantic 178 175 3 16,860 12,010 4,850
New Jersey 34 34 — 3,619 2,400 1,219
New York (excluding New York City) 63 63 — 3,487 2,450 1,037
New York City 38 37 1 756 397 359
Pennsylvania 43 41 2 8,998 6,763 2,235
East North Central 125 114 11 3,642 2,227 1,415
Illinois 30 26 4 395 242 153
Indiana 22 17 5 189 102 87
Michigan 26 25 1 413 276 137
Ohio 29 28 1 467 388 79
Wisconsin 18 18 — 2,178 1,219 959
West North Central 46 43 3 1,941 1,025 916
Iowa 7 7 — 303 70 233
Kansas 5 3 2 35 13 22
Minnesota 17 16 1 1,528 915 613
Missouri 15 15 — 17 2 15
Nebraska 2 2 — 10 4 6
North Dakota — — — 38 14 24
South Dakota — — — 10 7 3
South Atlantic 197 182 15 4,803 3,160 1,643
Delaware 4 3 1 641 619 22
District of Columbia 1 — 1 100 57 43
Florida 50 45 5 162 78 84
Georgia 25 25 — 18 2 16
Maryland 23 23 — 1,417 804 613
North Carolina 32 32 — 334 92 242
South Carolina 22 19 3 47 17 30
Virginia 31 28 3 1,199 788 411
West Virginia 9 7 2 885 703 182
East South Central 43 39 4 137 83 54
Alabama 7 6 1 66 44 22
Kentucky 9 8 1 22 12 10
Mississippi 4 4 — 4 4 —
Tennessee 23 21 2 45 23 22
West South Central 91 84 7 67 28 39
Arkansas 4 4 — 18 5 13
Louisiana 12 11 1 8 8 —
Oklahoma 10 10 — — — —
Texas 65 59 6 41 15 26
Mountain 39 37 2 88 40 48
Arizona 13 12 1 10 6 4
Colorado 12 11 1 8 8 —
Idaho 5 5 — 14 5 9
Montana — — — 8 6 2
Nevada 7 7 — 17 4 13
New Mexico — — — 7 4 3
Utah 2 2 — 19 5 14
Wyoming — — — 5 2 3
Pacific 155 152 3 255 111 144
Alaska 1 1 — 3 1 2
California 114 111 3 144 82 62
Hawaii 10 10 — N N N
Oregon 12 12 — 65 10 55
Washington 18 18 — 43 18 25
Territories 3 2 1 — — —
American Samoa N — — N N N
Commonwealth of Northern Mariana Islands — — — — — —
Guam — — — — — —
Puerto Rico 3 2 1 N N N
U.S. Virgin Islands — — — — — —
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
  • U: Unavailable — The data are unavailable.
  • * The 2019 annual tables exclude cases of nationally notifiable conditions and diseases among non-U.S. residents. As a result, data in Table 2 does not include a "Non-U.S. Resident" or "Total" row, that would have been included in the table had the data been stratified into the following four categories, based upon the "country of usual residence" (COUR) algorithm: U.S. Residents, excluding U.S. Territories; U.S. Territories; Non-US. Residents; and Total.Table 2 for the 2019 annual tables only includes the first two of these stratification categories.
  • † To calculate rates, use the populations provided in Table 8. Note that calculation of rates for the following conditions use population subsets presented in Table 8: Zika virus infection, congenital; Zika virus disease, congenital; Infant botulism; Congenital rubella syndrome; Perinatal Hepatitis B infection, Perinatal Hepatitis C infection, Haemophilus influenzae, invasive disease and Invasive pneumococcal disease, and Influenza associated pediatric mortality; see Table 8 (population reference table). Also see notes 3 and 7.
  • § Before 2019, probable cases were not reported, and cases in neonates ≤60 days of age were counted as one case in a mother-infant pair. Beginning in 2019, confirmed and probable cases are being reported, and maternal and neonatal cases are being counted separately.
Notes:
  1. These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables.
  2. The list of national notifiable infectious diseases and conditions for 2019 and their national surveillance case definitions are available by navigating to the Surveillance Case Definitions | CDC web page, selecting "2019" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2018 by CSTE for national surveillance that were implemented in January 2019. Candida auris, clinical became a new national notifiable condition, and revised case definitions were implemented for the following conditions: diphtheria, acute hepatitis A, listeriosis, yellow fever, Salmonella Paratyphi infection and Salmonella Typhi infection. Salmonella Paratyphi infection and Salmonella Typhi infection replaced Paratyphoid fever and Typhoid fever, respectively, as national notifiable conditions. Salmonellosis (excluding S. Typhi infection and S. Paratyphi infection) replaced Salmonellosis (excluding paratyphoid fever and typhoid fever) as a national notifiable condition. In addition, Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE) represents a consolidation of CP-CRE species Klebsiella spp, CP-CRE E. coli, and CP-CRE Enterobacter spp. Publication criteria for the finalized 2019 data are available at https://wonder.cdc.gov/nndss/documents/2019_NNDSS _Publication_Criteria_01212021.pdf. See also Guide to Interpreting Provisional and Finalized NNDSS Data.
  3. Population estimates for incidence rates are July 1st, 2019, estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for April 1, 2010, to July 1, 2019, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2019), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states released July 9, 2020, are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2019 mid-year estimates from the U.S. Census Bureau International Data Base, accessed on August 6, 2020, at https://www.census.gov/data-tools/demo/idb/#/country?YR_ANIM=2021. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation.
  4. Annual tables for 2016 and later years are available on CDC WONDER.
  5. Annual summary reports from 1993–2015 are available as published in the Morbidity and Mortality Weekly Report.
  6. NNDSS annual tables since 1952 are available at CDC Stacks (once in CDC Stacks, select "Annual Reports" in the "Genre" box to the left).
  7. For most conditions, national incidence rates are calculated as the number of reported cases for each infectious disease or condition divided by the U.S. resident population for the specified demographic population or the total U.S. resident population, multiplied by 100,000. When a national notifiable infectious condition is associated with a specific age restriction, the same restriction was applied to the population in the denominator of the incidence rate calculation. In addition, population data from reporting jurisdictions in which the disease or condition was not reportable or not available were excluded from the denominator of the incidence rate calculations.

    Age restrictions in the numerator and denominator are applied for the following childhood conditions:

    • Zika virus disease, congenital (age restriction in numerator and denominator is <1 year)
    • Zika virus infection, congenital (age restriction in numerator and denominator is <1 year)
    • Haemophilus influenzae, invasive disease <5 years (age restriction in numerator and denominator is <5 years)
    • Invasive pneumococcal disease <5 years (age restriction in numerator and denominator is <5 years)
    • Influenza associated pediatric mortality (age restriction in numerator and denominator is <18 years)
    • Infant botulism (age restriction in numerator and denominator is <1 year)
    • Congenital rubella syndrome (age restriction in numerator and denominator is <1 year)
    • Perinatal Hepatitis B infection (age restriction in numerator is ≤24 months, denominator is <24 months)
    • Perinatal Hepatitis C infection (age restriction in numerator is ≤36 months, denominator is <36 months).

    Data for congenital syphilis are aggregated by the infant's year of birth. The rate for congenital syphilis is based upon the number of reported cases per 100,000 live births, using natality data for 2019 (National Center for Health Statistics Natality 2019, as compiled from data provided by the Vital Statistics Cooperative Program). The mother's race and ethnicity are used for race- and ethnicity-specific rates of congenital syphilis cases. Congenital syphilis data are published in Syphilis Statistics in the sexually transmitted diseases (STD) surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) and in the historical archives of the STD surveillance report (https://www.cdc.gov/std/stats/archive.htm). The STD surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) updates congenital syphilis cases and rates over time.

  8. Surveillance data reported by other CDC programs might vary from data reported in these tables because of differences in 1) the date used to aggregate the data, 2) the timing of reports, 3) the source of the data, 4) surveillance case definitions, and 5) policies regarding case jurisdiction (i.e., which jurisdiction should submit the case notification to CDC).
  9. The following 24 jurisdictions may have incomplete data, due to the coronavirus disease 2019 (COVID-19) pandemic: Alaska, California, Connecticut, Delaware, District of Columbia, Florida, Idaho, Indiana, Kansas, Massachusetts, Minnesota, Missouri, Montana, Nebraska, New Hampshire, New York (excluding New York City), New York City, North Dakota, Ohio, Oklahoma, South Carolina, Tennessee, Texas, and West Virginia. In addition, the following 2 U.S. Territories may have incomplete data due to the COVID-19 pandemic: American Samoa and the U.S. Virgin Islands.
Suggested Citation: Acknowledgment:
  • CDC acknowledges the local, state, and territorial health departments that collected the data from a range of case ascertainment sources (e.g., healthcare providers, hospitals, laboratories) and reported these data to CDC's National Notifiable Diseases Surveillance System.