Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 8. Population Denominators for Rate Calculations, United States and U.S. Territories, 2019
Data from some jurisdictions may be incomplete due to the coronavirus disease 2019 (COVID-19) pandemic. Please see Note #9 at the bottom of the table.
Reporting Area Total Resident Population US Resident Population, by Age Subgroup Live Births in Year 2019††
Population ( Age <1 year)* Population (Age <24 months)† Population (Age <36 months)§ Population ( Age <5 years) Population (Age <18 years)**
United States 328,239,523 3,783,052 7,612,651 11,534,695 19,576,683 73,039,150 3,747,540
New England 14,845,063 145,600 293,082 443,012 749,794 2,902,835 142,529
Connecticut 3,565,287 34,625 70,167 106,513 181,710 727,440 34,258
Maine 1,344,212 12,035 24,390 37,101 63,537 248,842 11,779
Massachusetts 6,892,503 70,791 141,610 212,910 357,362 1,352,800 69,117
New Hampshire 1,359,711 12,052 24,346 37,205 63,621 255,253 11,839
Rhode Island 1,059,361 10,518 21,432 32,224 54,521 204,495 10,175
Vermont 623,989 5,579 11,137 17,059 29,043 114,005 5,361
Middle Atlantic 41,137,740 458,101 921,084 1,389,118 2,339,615 8,601,490 455,354
New Jersey 8,882,190 99,459 201,051 304,425 514,690 1,938,578 99,585
New York (excluding New York City) 11,116,744 115,307 233,718 354,272 603,283 2,311,536 116,136
New York City 8,336,817 108,623 214,201 318,754 523,718 1,716,763 105,403
Pennsylvania 12,801,989 134,712 272,114 411,667 697,924 2,634,613 134,230
East North Central 46,902,431 529,950 1,069,584 1,620,889 2,753,040 10,374,398 526,604
Illinois 12,671,821 143,723 289,659 439,163 746,934 2,817,875 140,128
Indiana 6,732,219 80,356 162,694 245,929 418,340 1,567,974 80,859
Michigan 9,986,857 109,018 219,873 333,798 566,442 2,143,933 107,886
Ohio 11,689,100 133,487 269,734 407,786 690,828 2,578,019 134,461
Wisconsin 5,822,434 63,366 127,624 194,213 330,496 1,266,597 63,270
West North Central 21,426,573 259,226 522,104 793,303 1,346,817 4,974,179 257,856
Iowa 3,155,070 37,540 75,836 115,022 195,636 726,841 37,649
Kansas 2,913,314 35,325 71,362 108,683 185,331 700,250 35,395
Minnesota 5,639,632 67,629 135,987 206,911 351,622 1,303,157 66,027
Missouri 6,137,428 71,012 143,146 217,232 368,080 1,370,585 72,127
Nebraska 1,934,408 25,252 50,631 76,974 130,880 476,074 24,755
North Dakota 762,062 10,483 21,030 32,084 54,101 180,171 10,454
South Dakota 884,659 11,985 24,112 36,397 61,167 217,101 11,449
South Atlantic 65,784,817 729,332 1,469,560 2,222,538 3,759,068 14,032,550 727,520
Delaware 973,764 10,618 21,289 32,350 54,719 203,572 10,562
District of Columbia 705,749 9,552 18,764 27,800 45,368 128,168 9,079
Florida 21,477,737 221,463 445,834 674,612 1,139,742 4,229,929 220,002
Georgia 10,617,423 127,141 255,907 387,551 656,566 2,503,881 126,371
Maryland 6,045,680 69,926 141,584 213,893 361,937 1,334,687 70,178
North Carolina 10,488,084 118,891 239,468 361,132 609,770 2,300,715 118,725
South Carolina 5,148,714 56,122 113,292 171,715 292,464 1,111,183 57,038
Virginia 8,535,519 97,864 197,689 299,132 505,477 1,860,848 97,429
West Virginia 1,792,147 17,755 35,733 54,353 93,025 359,567 18,136
East South Central 19,176,181 225,348 455,032 686,905 1,159,050 4,299,811 228,770
Alabama 4,903,185 56,901 115,191 174,264 294,357 1,088,306 58,615
Kentucky 4,467,673 53,154 107,266 161,730 272,610 1,002,871 53,069
Mississippi 2,976,149 35,518 71,756 108,721 183,478 698,583 36,636
Tennessee 6,829,174 79,775 160,819 242,190 408,605 1,510,051 80,450
West South Central 40,619,450 520,613 1,049,868 1,599,275 2,736,357 10,139,833 522,247
Arkansas 3,017,804 36,355 73,361 110,933 188,464 700,155 36,564
Louisiana 4,648,794 58,010 116,986 178,015 301,469 1,087,630 58,941
Oklahoma 3,956,971 48,442 97,927 149,364 255,533 952,238 49,143
Texas 28,995,881 377,806 761,594 1,160,963 1,990,891 7,399,810 377,599
Mountain 24,854,998 294,108 589,803 894,954 1,528,640 5,809,939 286,809
Arizona 7,278,717 81,929 164,994 250,720 429,788 1,640,236 79,375
Colorado 5,758,736 64,561 129,428 195,726 332,201 1,259,519 62,869
Idaho 1,787,065 22,106 44,473 67,530 116,200 448,201 22,063
Montana 1,068,778 11,659 23,199 35,545 61,156 228,588 11,079
Nevada 3,080,156 35,701 71,555 108,839 185,575 692,639 35,072
New Mexico 2,096,829 23,014 46,353 70,297 120,986 475,838 22,960
Utah 3,205,958 48,566 96,527 145,948 247,803 931,184 46,826
Wyoming 578,759 6,572 13,274 20,349 34,931 133,734 6,565
Pacific 53,492,270 620,774 1,242,534 1,884,701 3,204,302 11,904,115 599,851
Alaska 731,545 9,978 19,990 30,176 51,080 179,983 9,822
California 39,512,223 462,589 925,302 1,402,624 2,383,716 8,894,641 446,479
Hawaii 1,415,872 16,800 33,517 50,561 85,219 299,868 16,797
Oregon 4,217,737 43,312 87,338 132,800 227,811 866,562 41,858
Washington 7,614,893 88,095 176,387 268,540 456,476 1,663,061 84,895
U.S. Territories 3,672,195 31,808 63,546 95,354 162,350 706,775 25,155
American Samoa 50,826 917 1,843 2,780 4,650 17,418 —
Commonwealth of Northern Mariana Islands 51,994 763 1,517 2,268 3,755 16,004 566
Guam 167,772 3,181 6,362 9,552 15,921 54,170 3,165
Puerto Rico 3,294,626 25,634 51,171 76,736 131,230 594,123 21,424
U.S. Virgin Islands 106,977 1,313 2,653 4,018 6,794 25,060 —
  • * Use this population for Zika virus disease, congenital; Zika virus infection, congenital; Infant botulism; and Congenital rubella syndrome.
  • † Use this population for Perinatal Hepatitis B infection.
  • § Use this population for Perinatal Hepatitis C infection.
  • ¶ Use this population for Haemophilus influenzae, invasive disease and invasive pneumococcal disease.
  • ** Use this population for Influenza associated pediatric mortality.
  • †† Use this population for Congenital Syphilis. Please also see note 7 .
Notes:
  1. These are annual cases of selected infectious national notifiable diseases from the National Notifiable Diseases Surveillance System (NNDSS). NNDSS data reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published. Cases are reported by state health departments to CDC weekly. Because source datasets may be updated as additional information is received, statistics in publications based on that source data may differ from what is presented in these tables.
  2. The list of national notifiable infectious diseases and conditions for 2019 and their national surveillance case definitions are available by navigating to the Surveillance Case Definitions | CDC web page, selecting "2019" for the notifiable condition list year, checking "infectious" conditions, and clicking "Get Notifiable List by Year". This list incorporates the Council of State and Territorial Epidemiologists (CSTE) position statements approved in 2018 by CSTE for national surveillance that were implemented in January 2019. Candida auris, clinical became a new national notifiable condition, and revised case definitions were implemented for the following conditions: diphtheria, acute hepatitis A, listeriosis, yellow fever, Salmonella Paratyphi infection and Salmonella Typhi infection. Salmonella Paratyphi infection and Salmonella Typhi infection replaced Paratyphoid fever and Typhoid fever, respectively, as national notifiable conditions. Salmonellosis (excluding S. Typhi infection and S. Paratyphi infection) replaced Salmonellosis (excluding paratyphoid fever and typhoid fever) as a national notifiable condition. In addition, Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE) represents a consolidation of CP-CRE species Klebsiella spp, CP-CRE E. coli, and CP-CRE Enterobacter spp. Publication criteria for the finalized 2019 data are available at https://wonder.cdc.gov/nndss/documents/2019_NNDSS _Publication_Criteria_01212021.pdf. See also Guide to Interpreting Provisional and Finalized NNDSS Data.
  3. Population estimates for incidence rates are July 1st, 2019, estimates obtained from the National Center for Health Statistics (NCHS) postcensal estimates of the resident population of the United States for April 1, 2010, to July 1, 2019, by year, county, single year of age (range: 0 to 85 years), bridged-race (white, black or African American, American Indian or Alaska Native, Asian, or Pacific Islander), Hispanic ethnicity (not Hispanic or Latino, Hispanic or Latino), and sex (Vintage 2019), prepared under a collaborative arrangement with the U.S. Census Bureau. Population estimates for states released July 9, 2020, are available at https://www.cdc.gov/nchs/nvss/bridged_race/data_documentation.htm. Population estimates for territories are the 2019 mid-year estimates from the U.S. Census Bureau International Data Base, accessed on August 6, 2020, at https://www.census.gov/data-tools/demo/idb/#/country?YR_ANIM=2021. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation.
  4. Annual tables for 2016 and later years are available on CDC WONDER.
  5. Annual summary reports from 1993–2015 are available as published in the Morbidity and Mortality Weekly Report.
  6. NNDSS annual tables since 1952 are available at CDC Stacks (once in CDC Stacks, select "Annual Reports" in the "Genre" box to the left).
  7. For most conditions, national incidence rates are calculated as the number of reported cases for each infectious disease or condition divided by the U.S. resident population for the specified demographic population or the total U.S. resident population, multiplied by 100,000. When a national notifiable infectious condition is associated with a specific age restriction, the same restriction was applied to the population in the denominator of the incidence rate calculation. In addition, population data from reporting jurisdictions in which the disease or condition was not reportable or not available were excluded from the denominator of the incidence rate calculations.

    Age restrictions in the numerator and denominator are applied for the following childhood conditions:

    • Zika virus disease, congenital (age restriction in numerator and denominator is <1 year)
    • Zika virus infection, congenital (age restriction in numerator and denominator is <1 year)
    • Haemophilus influenzae, invasive disease <5 years (age restriction in numerator and denominator is <5 years)
    • Invasive pneumococcal disease <5 years (age restriction in numerator and denominator is <5 years)
    • Influenza associated pediatric mortality (age restriction in numerator and denominator is <18 years)
    • Infant botulism (age restriction in numerator and denominator is <1 year)
    • Congenital rubella syndrome (age restriction in numerator and denominator is <1 year)
    • Perinatal Hepatitis B infection (age restriction in numerator is ≤24 months, denominator is <24 months)
    • Perinatal Hepatitis C infection (age restriction in numerator is ≤36 months, denominator is <36 months).

    Data for congenital syphilis are aggregated by the infant's year of birth. The rate for congenital syphilis is based upon the number of reported cases per 100,000 live births, using natality data for 2019 (National Center for Health Statistics Natality 2019, as compiled from data provided by the Vital Statistics Cooperative Program). The mother's race and ethnicity are used for race- and ethnicity-specific rates of congenital syphilis cases. Congenital syphilis data are published in Syphilis Statistics in the sexually transmitted diseases (STD) surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) and in the historical archives of the STD surveillance report (https://www.cdc.gov/std/stats/archive.htm). The STD surveillance report (https://www.cdc.gov/std/syphilis/stats.htm) updates congenital syphilis cases and rates over time.

  8. Surveillance data reported by other CDC programs might vary from data reported in these tables because of differences in 1) the date used to aggregate the data, 2) the timing of reports, 3) the source of the data, 4) surveillance case definitions, and 5) policies regarding case jurisdiction (i.e., which jurisdiction should submit the case notification to CDC).
  9. The following 24 jurisdictions may have incomplete data, due to the coronavirus disease 2019 (COVID-19) pandemic: Alaska, California, Connecticut, Delaware, District of Columbia, Florida, Idaho, Indiana, Kansas, Massachusetts, Minnesota, Missouri, Montana, Nebraska, New Hampshire, New York (excluding New York City), New York City, North Dakota, Ohio, Oklahoma, South Carolina, Tennessee, Texas, and West Virginia. In addition, the following 2 U.S. Territories may have incomplete data due to the COVID-19 pandemic: American Samoa and the U.S. Virgin Islands.
Suggested Citation: Acknowledgment:
  • CDC acknowledges the local, state, and territorial health departments that collected the data from a range of case ascertainment sources (e.g., healthcare providers, hospitals, laboratories) and reported these data to CDC's National Notifiable Diseases Surveillance System.