Notice: Improvements in data processing at CDC were applied to 2020 and 2021 data beginning with the tables published for week 47. Case count changes between tables published for week 46 and week 47 may be due to changes in data processing rules and not due to changes in disease levels.

Nationally Notifiable Infectious Diseases and Conditions, United States: Weekly Tables

TABLE 1hh. Weekly cases* of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents week ending December 25, 2021 (Week 51)
Reporting Area Syphilis
Congenital Primary and secondary
Current weekPrevious 52 weeks Max †Cum YTD 2021 †Cum YTD 2020 †Current weekPrevious 52 weeks Max †Cum YTD 2021 †Cum YTD 2020 †
U.S. Residents, excluding U.S. Territories - 44 1,641 2,087 68 980 40,782 40,267
New England - 2 8 13 - 28 857 1,029
Connecticut - 1 2 2 - 7 2 272
Maine - 0 - - - 4 54 35
Massachusetts - 1 4 10 - 23 622 594
New Hampshire - 0 - - - 4 71 48
Rhode Island - 1 1 1 - 9 100 77
Vermont - 1 1 - - 4 8 3
Middle Atlantic - 3 51 65 18 115 3,837 4,679
New Jersey - 3 29 24 - 27 610 728
New York (excluding New York City) - 2 12 27 14 41 1,172 761
New York City - 0 - - 4 57 1,991 2,177
Pennsylvania - 1 10 14 - 22 64 1,013
East North Central - 6 99 99 1 124 4,308 4,079
Illinois - 2 19 26 - 48 1,017 1,423
Indiana - 0 - 6 - 23 538 504
Michigan - 3 32 28 - 28 896 770
Ohio - 3 40 33 - 44 1,361 1,039
Wisconsin - 2 8 6 1 20 496 343
West North Central - 4 39 53 1 66 2,284 1,714
Iowa - 2 8 1 - 13 270 186
Kansas - 1 6 8 - 4 53 147
Minnesota - 2 12 7 - 20 515 405
Missouri - 1 1 30 1 33 998 786
Nebraska - 1 - 1 - 8 162 102
North Dakota - 1 1 3 - 4 38 32
South Dakota - 2 11 3 - 10 248 56
South Atlantic - 11 243 338 13 236 8,948 8,939
Delaware - 1 1 2 - 6 95 97
District of Columbia - 0 - 3 - 10 199 238
Florida - 8 136 150 1 109 4,138 3,342
Georgia - 2 20 81 - 60 1,176 1,715
Maryland - 2 24 30 - 27 706 841
North Carolina - 3 36 30 - 45 1,353 1,278
South Carolina - 1 3 19 - 19 425 627
Virginia - 2 19 15 12 30 722 680
West Virginia - 1 4 8 - 8 134 121
East South Central - 5 101 101 4 77 2,471 2,412
Alabama - 3 35 20 4 24 712 519
Kentucky - 1 12 13 - 20 326 420
Mississippi - 3 26 37 - 21 660 728
Tennessee - 3 28 31 - 31 773 745
West South Central - 16 428 676 - 126 4,811 4,700
Arkansas - 3 39 21 - 29 897 491
Louisiana - 1 2 62 - 30 738 669
Oklahoma - 6 67 49 - 20 85 908
Texas - 14 320 544 - 85 3,091 2,632
Mountain - 9 192 229 1 118 3,730 3,471
Arizona - 7 116 116 - 48 1,511 1,409
Colorado - 2 19 21 - 40 650 623
Idaho - 1 5 2 1 7 81 61
Montana - 2 6 1 - 11 95 43
Nevada - 3 26 45 - 39 676 747
New Mexico - 2 19 42 - 26 577 450
Utah - 1 1 1 - 6 128 127
Wyoming - 0 - 1 - 2 12 11
Pacific - 15 480 513 30 249 9,536 9,244
Alaska - 1 4 7 - 9 153 172
California - 14 411 467 6 205 7,894 7,456
Hawaii - 1 - 11 - 2 - 178
Oregon - 3 27 18 12 31 912 611
Washington - 3 38 10 12 21 577 827
U.S. Territories - 1 2 4 - 9 189 269
American Samoa - 0 - - - 0 - -
Commonwealth of Northern Mariana Islands - 0 - - - 0 - -
Guam - 0 - - - 0 - -
Puerto Rico - 1 2 4 - 9 189 269
U.S. Virgin Islands - 0 - - - 0 - -
Non-U.S. Residents - 0 - - - 0 - 1
Total - 44 1,643 2,091 68 988 40,971 40,537
  • U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
  • -: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
  • NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
  • NP: Nationally notifiable but not published.
  • NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
  • Cum: Cumulative year-to-date counts.
  • Max: Maximum — Maximum case count during the previous 52 weeks.
  • * Case counts for reporting year 2021 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
  • †Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).