Notice: Improvements in data processing at CDC were applied to 2020 and 2021 data beginning with the tables published for week 47. Case count changes between tables published for week 46 and week 47 may be due to changes in data processing rules and not due to changes in disease levels.

Nationally Notifiable Infectious Diseases and Conditions, United States: Weekly Tables

TABLE 1t. Weekly cases* of notifiable diseases, United States, U.S. Territories, and Non-U.S. Residents week ending December 25, 2021 (Week 51)
Reporting Area Invasive pneumococcal disease, age <5 years § Legionellosis
Confirmed Probable
Current weekPrevious 52 weeks Max †Cum YTD 2021 †Cum YTD 2020 †Current weekPrevious 52 weeks Max †Cum YTD 2021 †Cum YTD 2020 †Current weekPrevious 52 weeks Max †Cum YTD 2021 †Cum YTD 2020 †
U.S. Residents, excluding U.S. Territories 1 21 424 480 - 2 23 24 24 340 6,729 5,859
New England - 2 18 22 - 1 1 - - 31 456 298
Connecticut - 1 6 4 - 0 - - - 8 85 81
Maine - 1 1 - - 0 - - - 5 35 11
Massachusetts - 1 10 14 - 1 1 - - 19 209 133
New Hampshire - 1 1 1 - 0 - - - 6 44 32
Rhode Island - 0 - 3 - 0 - - - 8 81 34
Vermont - 0 - - - 0 - - - 1 2 7
Middle Atlantic - 4 72 67 - 1 5 1 5 110 1,404 1,244
New Jersey - 3 17 18 - 1 3 - - 4 65 236
New York (excluding New York City) - 3 21 14 - 1 1 - 5 50 594 345
New York City - 3 14 12 - 1 1 - - 23 357 318
Pennsylvania - 3 20 23 - 0 - 1 - 37 388 345
East North Central - 6 65 80 - 2 9 11 2 158 1,987 1,489
Illinois - 0 - - - 0 - - - 69 473 328
Indiana - 1 8 17 - 0 - - 2 15 177 150
Michigan - 3 18 22 - 1 1 1 - 46 401 373
Ohio - 3 31 28 - 2 8 10 - 122 811 401
Wisconsin - 3 8 13 - 0 - - - 13 125 237
West North Central 1 2 27 36 - 1 2 7 - 17 268 315
Iowa N NC N N N NC N N - 3 39 32
Kansas - 0 - - - 0 - - - 5 41 50
Minnesota - 1 - 12 - 0 - - - 9 123 94
Missouri 1 2 20 17 - 1 1 5 - 3 18 107
Nebraska - 1 2 3 - 0 - - - 2 26 16
North Dakota - 1 1 - - 0 - - - 1 5 6
South Dakota - 1 4 4 - 1 1 2 - 2 16 10
South Atlantic - 6 100 91 - 1 4 1 1 50 1,148 1,188
Delaware - 1 1 3 - 0 - - - 3 21 14
District of Columbia - 0 - 1 - 0 - - - 0 - 7
Florida - 5 52 31 - 1 3 1 - 20 474 411
Georgia - 2 30 21 - 0 - - - 8 141 145
Maryland - 1 4 7 - 0 - - - 15 159 179
North Carolina N NC N N N NC N N - 11 118 128
South Carolina - 2 8 11 - 1 1 - 1 6 83 56
Virginia - 1 5 11 - 0 - - - 10 146 200
West Virginia - 0 - 6 - 0 - - - 3 6 48
East South Central - 4 46 44 - 0 - - - 20 322 309
Alabama - 2 14 12 - 0 - - - 6 86 58
Kentucky - 2 7 3 - 0 - - - 9 100 67
Mississippi - 2 16 12 - 0 - - - 1 3 33
Tennessee - 2 9 17 - 0 - - - 12 133 151
West South Central - 4 52 68 - 1 1 2 4 96 401 320
Arkansas - 2 15 12 - 0 - - 1 5 38 38
Louisiana - 3 13 18 - 0 - - - 4 53 50
Oklahoma - 0 - - - 0 - - - 26 1 -
Texas - 3 24 38 - 1 1 2 3 67 309 232
Mountain - 3 38 67 - 1 1 2 4 14 317 260
Arizona - 2 16 19 - 0 - 1 3 6 103 87
Colorado - 0 - 18 - 0 - - 1 5 105 73
Idaho - 0 - - - 0 - - - 2 19 15
Montana - 0 - 2 - 0 - - - 1 9 7
Nevada - 1 6 7 - 0 - - - 2 22 25
New Mexico - 1 3 8 - 0 - - - 2 16 17
Utah - 1 12 13 - 1 1 1 - 3 38 31
Wyoming - 1 1 - - 0 - - - 1 5 5
Pacific - 2 6 5 - 0 - - 8 75 426 436
Alaska - 1 3 1 - 0 - - - 1 2 2
California N NC N N N NC N N 8 11 296 375
Hawaii - 1 3 4 - 0 - - - 1 8 14
Oregon N NC N N N NC N N - 7 63 45
Washington N NC N N N NC N N - 68 57 -
U.S. Territories - 0 - - - 0 - - - 2 8 3
American Samoa N NC N N N NC N N N NC N N
Commonwealth of Northern Mariana Islands - 0 - - - 0 - - - 0 - -
Guam - 0 - - - 0 - - - 0 - -
Puerto Rico - 0 - - - 0 - - - 2 7 3
U.S. Virgin Islands - 0 - - - 0 - - - 1 1 -
Non-U.S. Residents - 0 - - - 0 - - - 1 2 -
Total 1 21 424 480 - 2 23 24 24 340 6,739 5,862
  • U: Unavailable — The reporting jurisdiction was unable to send the data to CDC or CDC was unable to process the data.
  • -: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
  • NN: Not nationally notifiable — This condition was not designated as being nationally notifiable.
  • NP: Nationally notifiable but not published.
  • NC: Not calculated — There is insufficient data available to support the calculation of this statistic.
  • Cum: Cumulative year-to-date counts.
  • Max: Maximum — Maximum case count during the previous 52 weeks.
  • * Case counts for reporting year 2021 are provisional and subject to change. Cases are assigned to the reporting jurisdiction submitting the case to NNDSS, if the case's country of usual residence is the U.S., a U.S. territory, unknown, or null (i.e. country not reported); otherwise, the case is assigned to the 'Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions. For further information on interpretation of these data, see https://www.cdc.gov/nndss/docs/Readers-Guide-WONDER-Tables-20210421-508.pdf.
  • †Previous 52 week maximum and cumulative YTD are determined from periods of time when the condition was reportable in the jurisdiction (i.e., may be less than 52 weeks of data or incomplete YTD data).
  • § Includes drug resistant and susceptible cases of Invasive Pneumococcal Disease.