Nationally Notifiable Infectious Diseases and Conditions, United States: Annual Tables

TABLE 2t. Annual reported cases* of notifiable diseases, by region and reporting area, United States, U.S. Territories, and Non-U.S. Residents, 2021
Reporting Area Yellow fever Zika virus
Zika virus disease, congenital § Zika virus disease, non-congenital Zika virus infection, congenital § Zika virus infection, non-congenital
U.S. Residents, excluding U.S. Territories 1 1 2
New England
Connecticut
Maine
Massachusetts
New Hampshire
Rhode Island
Vermont
Middle Atlantic 1
New Jersey
New York (excluding New York City)
New York City
Pennsylvania 1
East North Central
Illinois
Indiana
Michigan
Ohio
Wisconsin
West North Central
Iowa
Kansas
Minnesota
Missouri
Nebraska
North Dakota
South Dakota
South Atlantic
Delaware
District of Columbia
Florida
Georgia
Maryland
North Carolina
South Carolina
Virginia
West Virginia
East South Central
Alabama
Kentucky
Mississippi
Tennessee
West South Central 1
Arkansas
Louisiana
Oklahoma
Texas 1
Mountain
Arizona
Colorado
Idaho N
Montana
Nevada
New Mexico
Utah
Wyoming
Pacific 2
Alaska
California 2
Hawaii
Oregon
Washington
U.S. Territories 32 11
American Samoa
Commonwealth of Northern Mariana Islands
Guam
Puerto Rico 32 11
U.S. Virgin Islands
Non-U.S. Residents
Total 1 1 34 11
  • —: No reported cases — The reporting jurisdiction did not submit any cases to CDC.
  • N: Not reportable — The disease or condition was not reportable by law, statute, or regulation in the reporting jurisdiction.
  • U: Unavailable — The data are unavailable.
  • * Cases are assigned to the reporting jurisdiction submitting the case to NNDSS if the case's country of usual residence is the United States, a U.S. territory, unknown, or country is not reported; otherwise, the case is assigned to the Non-U.S. Residents' category. Country of usual residence is currently not reported by all jurisdictions or for all conditions because this data element is only available in the HL7 generic version 2 and disease-specific message mapping guides. If a jurisdiction sends data in legacy formats, they are not able to send this information. For further information on interpretation of these data, see https://www.cdc.gov/nndss/data-statistics/readers-guides/.
  • † To calculate rates, use the populations provided in Table 8. Note that calculation of rates for the following conditions uses population subgroups as described in note #7 and population counts presented in Table 8: Zika virus infection, congenital; Zika virus disease, congenital; Infant botulism; Congenital rubella syndrome; Perinatal Hepatitis B infection; Perinatal Hepatitis C infection; Haemophilus influenzae, invasive disease; Invasive pneumococcal disease; and Influenza-associated pediatric mortality. Also see Notes #3 and #7.
  • § Data reported to ArboNET using the national surveillance case definition for congenital Zika virus infection (CSTE Position Statement 16-ID-01).