Online Tuberculosis Information System (OTIS)

Online Tuberculosis Information System Summary

Summary:    Disease Incidence:   The Online Tuberculosis Information System (OTIS) contains information on verified tuberculosis (TB) cases reported to the Centers for Disease Control and Prevention (CDC) by state health departments, the District of Columbia and Puerto Rico from 1993 through 2023. These data were extracted from the CDC National TB Surveillance System (NTSS). Data for 27 variables are included in the 2022 data set and users are able to produce cross-tabulations with multi-level stratification. Each year these data are updated with an additional year of cases plus revisions to cases reported in previous years.

Population:   All persons reported as TB cases, 1993 through 2023. The 1993-2023 data includes case report updates received by July 17, 2024.

Source:    Tuberculosis Reports:   U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention (CDC), Division of Tuberculosis Elimination (DTBE), Surveillance, Epidemiology and Outbreak Investigations Branch (SEOIB).

Population Estimates for Rates:   2020 to 2023 (Vintage 2023) postcensal estimates of the July 1 resident population by year, county, age groups, race, sex, and Hispanic origin https://www2.census.gov/programs-surveys/popest/datasets/2020-2023/counties/asrh released by the US Census Bureau on June 27, 2024. The methodology states the 2020-2023 series of estimates are based on the Modified Blended Base produced by the US Census Bureau in lieu of the April 1, 2020 decennial population count. The Modified Blended Base consists of the blend of Vintage 2020 postcensal population estimates for April 1, 2020, the 2020 Demographic Analysis Estimates, and 2020 Census data from the internal Census Edited File (CEF) (see The 2020-2023 Population Estimates Methodology). Population estimates for incidence rates are July 1st, 2022 postcensal estimates of the resident population of the United States for July 1, 2020, to July 1, 2022, by year, county, single year of age (range: 0 to 85+ years), bridged-race (American Indian or Alaska Native, Asian or Pacific Islander, Black or African American, White), Hispanic ethnicity (Hispanic or Latino, not Hispanic or Latino), and sex (Female, Male), prepared under a collaborative arrangement with the U.S. Census Bureau and the National Cancer Institute (NCI). The "Vintage 2022" population estimates for years 2020-2022 were released March 2024 by the National Cancer Institute. 2010 to 2020 (Vintage 2020) postcensal estimates of the July 1 resident population by year, county, age groups, race, sex, and Hispanic origin released by the Census Bureau on July 27, 2021. The methodology states the 2010 - 2020 series of estimates are based on the April 1st, 2010 Census counts. National population denominators for the years 1993-2020 are from the National Center for Health Statistics "bridged-race" series of estimates. The population estimates for the resident population in years 2000-2020 were prepared under a collaborative arrangement with the U.S. Census Bureau. The postcensal estimates for years 2010-2020 are based on the April 1, 2010 bridged-single-race estimates resident population. The revised intercensal population estimates for 2000-2009 that are included in OTIS 2010 incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident population; this series of revised intercensal estimates was released by the National Center for Health Statistics (NCHS) on October 26, 2012. The postcensal estimates for years 2000-2009 that are included in previous releases of OTIS (archive OTIS 2003 - OTIS 2009) are based on the April 1, 2000 bridged-single-race estimates resident population. The intercensal population estimates for 1990-1999 incorporate the bridged-single-race estimates of the April 1, 2000 resident population and were prepared by the U.S. Census Bureau with support from the National Cancer Institute. Note that the population figures and resulting incidence rates in OTIS may differ slightly from rates in previous publications and reports that used different population sources. See Population Sources below for more information.

In WONDER:    Produce tables, maps, charts, and data extracts. Obtain summary statistical measures, including incidence counts (the number of cases) and rates, show the percentage of cases that have completed therapy in less than 1 year of initiating therapy, and the percentage of cases with initial drug susceptibility testing done with drug susceptibility testing to isoniazid (INH) and rifampin (RIF). Select specific disease, demographic and risk factor criteria to produce cross-tabulated incidence measures. National and state data are available in OTIS 2023. OTIS 2021 and prior releases share data in three levels of geographic detail: national, state and Metropolitan Statistical Areas (MSAs). The population estimates used as the denominator for rate calculations are also shown. Note: drug susceptibility testing measures and variables, and state rates are available only for OTIS 2005 data and later.

Limit and index your data by any and all of these variables:

  1. Location - National, State, or Metropolitan Statistical Area (MSA data are not available in OTIS 2022-2023)
  2. Year of Diagnosis - 1993-2023, or the last 5 years combined (2019-2023 in the OTIS 2023 data)
  3. Age Groups - 2 sets of age groups are available.
    1. Broad with 7 categories: 0-4 years; 5-14 years; 15-24 years; 25-44 years; 45-64 years; 65+ years; Not Reported
      or
    2. Standard with 12 categories: < 1 year; 1-4 years; 5-14 years; 15-24 years; 25-34 years; 35-44 years; 45-54 years; 55-64 years; 65-74 years; 75-84 years; 85+ years; Not Reported
  4. Sex - All, Female, Male, Not Reported
  5. Race / Ethnicity Race or Ethnicity - 2 sets of race / ethnicity categories are available:
    1. Bridged Race / Ethnicity with 6 categories: American Indian or Alaska Native, Non-Hispanic; Asian or Pacific Islander, Non-Hispanic; Black or African American, Non-Hispanic; Hispanic or Latino; White, Non-Hispanic; Not Reported
      or
    2. Single Race / Ethnicity with 9 categories, available in OTIS 2012 and later releases: American Indian or Alaska Native, Non-Hispanic; Asian, Non-Hispanic, Black or African American, Non-Hispanic; Hispanic or Latino; Multiple Race, Non-Hispanic; Native Hawaiian or Other Pacific Islander, Non-Hispanic; White, Non-Hispanic; Not Reported; Non-Hispanic Other(Non-Hispanic Other available with 2023 data and later)
  6. Occupation - Not available in OTIS 2022-2023. Three sets of occupation categories are available in prior releases:
    1. Historical Occupation available in OTIS 2010-2021: Correctional, Health Care, Migratory Agricultural, Other, Multiple, Not Employed, Not Reported, Invalid (Historic Occupation data for 2009 and later years are reported as "Invalid" in OTIS 2010-2021)
      or
    2. Revised Occupation available in OTIS 2010-2021: Correctional, Health care, Migratory Agricultural, Not Employed, Not Seeking Employment, Other, Retired, Not Reported, Invalid (Revised occupation data for 1993-2008 are reported as "Invalid" in OTIS 2010-2021).
      or
    3. Occupation available in OTIS 2009: Health Care; Correctional; Migratory Agricultural; Other; Multiple; Not Employed; Not Reported; Unavailable (all 2009 Occupation data are coded as "Unavailable" in OTIS 2009 only).
  7. Origin of Birth - U.S. Born, Non-U.S.–born, Not Reported
  8. Years in U.S. - Under 1 year, 1-4 years, 5-9 years, 10-14 years, 15-19 years, 20-24 years, 25-29 years, 30-34 years, 35-39 years, >=40 years, Unknown, Not Reported
  9. HIV Status - Positive, Negative, Indeterminate, Not Reported
  10. Homeless in the Past Year? - Yes, No, Not Reported
  11. Residing in a Correctional Facility? - Yes, No, Not Reported
  12. Residing in a Long Term Care Facility? - Yes, No, Not Reported
  13. Place of Residence at Diagnosis? - Correctional Facility, Long Term Care Facility, Not in a Facility, Not Reported
  14. Alcohol Use - Yes, No, Not Reported
  15. Drug Use, Injecting - Yes, No, Not Reported
  16. Drug Use, Non-injecting - Yes, No, Not Reported
  17. Diabetes - Yes, No, Not Reported (Diabetes data available in OTIS 2022 and later)
  18. Smoker Status - Current Smoker Everday, Current Smoker Somedays, Former, Never, Current Smoker Unknown, Not Reported (Smoker Status data available in OTIS 2023)
  19. Disease Site - Pulmonary, Extrapulmonary, Both, Not Reported
  20. Multidrug-Resistant - Yes, No, Not Reported, Not Applicable
  21. Previous TB - Yes, No, Not Reported
  22. Verification Criteria - Positive Culture, Positive Nucleic Acid Amplification Test, Positive Smear, Clinical Case Definition, Provider Diagnosis
  23. Receives Directly Observed Therapy? - Directed therapy Only, Self-administered Only, Both, Not Reported, Not Applicable (Beginning in OTIS 2023, known electronic directly observed therapy is merged with conventional in-person directly observed therapy.)
  24. Completion of Therapy Within One Year - No, Yes, Not Reported, Not Applicable
  25. Tested for Isoniazid Susceptibility - No, Yes, Not Applicable (OTIS 2005 and later only)
  26. Tested for Isoniazid & Rifampin Susceptibility - No, Yes, Not Applicable (OTIS 2005 and later only)
  27. Vital Status - Alive, Dead, Not Reported

Please refer to the following topics:

OTIS Data Request
Data Source Information
Additional Information

OTIS Data Request

Output:   

Produce tables, maps, charts, and extracts. Obtain summary statistical measures, including incidence counts (the number of cases) and rates, show the percentage of cases that have completed therapy in less than 1 year of initiating therapy, and calculate the percentage of cases with initial drug susceptibility testing done with drug susceptibility testing to isoniazid (INH) and rifampin (RIF). Select specific disease, demographic and risk factor criteria to produce cross-tabulated incidence measures. (Note: drug susceptibility testing measures and variables, and state rates are available only for OTIS 2005 data and later.)

Variables:   

You can limit and index your data by any and all of the data variables.

How?   

The Request screen has sections to guide you through making a data request as step-by-step process. However, to get your first taste of how the system works, you might want to simply press any Send button, and execute the default data request. The data results for your query appear on the Table screen. After you get your data results, try the Chart and Map screens. Or export your data to a file (tab-delimited line listing) for download to your computer.
For more information, see the following:
Quick Start Guide;
Step 1, Select and order results;
Step 2, Select location and time;
Step 3, Select demographics;
Step 4, Select risk factors;
Step 5, Select disease criteria;
Step 6, Select therapy issues;
Step 7, Other Options.

'By-Variables'   

Select variables that serve as keys (indexes) for organizing your data. See How do I organize my data? for more information.
Note:   To map your data, you must select at least one geographical location as a "By-Variable" for grouping your data, such as Region or State.

Help:   

Click on any button labeled "Help", located to the right-hand side of the screen at the top of each section. Each Control's label, such as the "Location" label next to the Location entry box, is linked to the on-line help for that item.

Send:   

Sends your data request to be processed on the CDC WONDER databases. The Send buttons are located on the bottom of the Request page, and also in the upper right corner of each section, for easy access.


Step 1. Organize table layout:
Group Results By:   

Select up to five variables that serve as keys for grouping your data. See Group Results By below for hints.

Measures:   

The number of cases, or frequency counts of TB cases that meet query criteria are reported in the results by default. You can also select the following optional measures for inclusion in the results.

Include Rates:   

Select the check box to report incidence rates per 100,000 persons and the populations used to calculate the rates. Rates are only available for fields that have corresponding population data: Year, Age Groups, Sex, Bridged Race/Ethnicity, and State. Note: are optional for OTIS 2005 and later only, and state rates are available only for OTIS 2005 and later data.

Include Completion of Therapy Within One Year:   

Select the check box to report the percentage of cases that completed therapy in less than or equal to 366 days of initiating therapy.

Include Drug Susceptibility Testing for
Isoniazid (INH):

  

Select the check box to report the percentage of cases with initial drug susceptibility testing done with test results for Isoniazid susceptibility. (Note: drug susceptibility testing measures are available only for OTIS 2005 and later.)

Include Drug Susceptibility Testing
for Isoniazid (INH) and Rifampin (RIF):

  

Select the check box to report the percentage of cases with initial drug susceptibility testing done with test results for Isoniazid and Rifampin susceptibility. (Note: drug susceptibility testing measures are available only for OTIS 2005 and later.)

Title:   

Enter any desired description to display as a title with your results.

The following statistical measures are available as query results:

  1. Disease Incidence Counts (the number of cases).
  2. Disease Incidence Rates for national data, and for state data in OTIS 2005 and later. The population figures used as the denominator for the rate calculations are also shown.
  3. Percent of total data results.
  4. Completion of Therapy Within One Year (COT): percentage of cases that completed therapy in less than or equal to 366 days of initiating therapy. The numerator, "Cases that Completed Therapy within a Year" and the denominator, "Cases Eligible for Completion for Therapy" are also shown.
  5. Percentage Tested for Drug Susceptibility to Isoniazid (INH): percentage of cases with initial drug susceptibility testing done reporting test results (OTIS 2005 and later only). The denominator, "Cases with Initial Drug Susceptibility Testing Done" is also shown.
  6. Percentage Tested for Drug Susceptibility to Isoniazid (INH) and Rifampin (RIF): percentage of cases with initial drug susceptibility testing done reporting test results (OTIS 2005 and later only). The denominator, "Cases with Initial Drug Susceptibility Testing Done" is also shown.

Group Results By...

Select up to five variables that serve as keys for grouping your data. For example, you could select to group (summarize, stratify, index) your data by Location (State or MSA) and Verification Criteria.

How?    See How do I organize my data? for more information.

Hints:   

  1. To make a map, you must request data with a geographic location variable, such as Region or State, as a "By-Variable." Then click the Map tab.
  2. You cannot make charts when your data has more than two By-Variables.
  3. You cannot group the data by both State and by Metropolitan Statistical Area (MSA). You can group by State only when you have chosen State locations. You can group by MSA only when you have chosen MSA locations. MSA data are not available in OTIS 2022 and later.
  4. You cannot group the data by Year when specific Risk-Factor or Demographic data values are shown.
  5. You cannot group the data by specific Risk-Factor or Demographic data values, unless the requested time period is "All Years" or the last 5 years (for example, 2018-2022 in the OTIS 2022 data).
  6. When rates are calculated, you can only group the data by those variables that have population denominator data, such as Age Group, Sex, Race, and Year. Note that these 4 variables with population denominator data are also the only variables that you can limit or restrict when calculating rates.

Percent

Percent is a column reported in the output for your data query. The Percent column shows the percentage of each row's cases in comparison to the total data results for your query. The sum of the column is 100%, all results for your data request.


Cases

The number of cases is shown in a column in the results table for your data query. A case is counted only once within any consecutive 12-month period. However, a patient who had verified disease in the past is counted again if the case was discharged from supervision (e.g., completed anti-tuberculosis therapy) or lost to supervision for more than 12 months and disease can be verified again. The case is not counted a second time if 12 months have not passed since the case was discharged from supervision. Mycobacterial diseases other than those caused by M. tuberculosis complex are not counted in tuberculosis morbidity statistics unless there is concurrent M. tuberculosis.

CDC's national morbidity reports have traditionally counted all cases; those that meet the standard published case definition and those that are verified by the reporting areas. When the standard case definition is not met, areas are given the option of verifying using other sets of local criteria such as contact to an infectious case or immunosuppression status. In this circumstance, the criteria used to verify the case of TB are categorized as "Provider Diagnosis." For more information, see Appendix B at https://www.cdc.gov/tb-data/?CDC_AAref_Val=https://www.cdc.gov/tb/statistics/reports/2023/Appendix-B.html.


Rates

Rate is a column reported in the output for your data query. Rates are expressed as the number of cases reported each calendar year per 100,000 population.

Population denominators used to calculate national and state rates for the years 1993-2020 were obtained from the National Center for Health Statistics bridged-race population counts. Population denominators used to calculate national and state rates for the years 2021-2022 were obtained from the National Center for Health Statistics single-race population and counts. Population denominators used to calculate bridged race rates for the years 2021-2022 were prepared under a collaborative arrangement with the U.S. Census Bureau and the National Cancer Institute (NCI). See Population Sources for more information.

Notes:
  • Rates are available in OTIS by year, state, age groups, sex, and race / ethnicity. Rates are available by
    • Bridged race ethnicity for cases in years 1993-2023 in OTIS 2012 and later releases, or
    • Race / ethnicity for cases in years 1993-2010 in OTIS 2010 and later releases.
  • Rates and the population denominators for rate calculations are not available for
    • In Otis vintages 2021-2022 cases diagnosed in 2021-2022: "Not Applicable" is displayed for rates and population denominators for years 2021-2022, because population estimates for United States in years 2021-2022 were not included in OTIS 2021 nor OTIS 2022.
    • Bridged race / ethnicity categories for cases diagnosed in 2021 and later years; or
    • Single race / ethnicity categories in OTIS 2018 and later releases; and
    • Puerto Rico by any data field other than Year.
  • Limited data fields:
    • When rates are requested, the query must group results by data fields that have corresponding population denominator data, such as age, sex, race /ethnicity, year and state.
    • When rates are requested, the query can filter, limit or restrict only those variables with population denominator data, such as age, sex, race /ethnicity, year and state.
    • State and national rates are available in OTIS 2005 and later releases. Rates are only available for national-level data in OTIS 2004 and prior releases.
  • When are national rates available?
    • National rates are available. For example, when the selected location is "The United States" and the data results are not grouped by State or grouped by Metropolitan Statistical Area (MSA), then national rates are shown. If each of the 50 states plus the District of Columbia (DC) is selected in the State list, then the national rate is shown. Metropolitan Statistical Area (MSA) data are not available in OTIS 2022-2023.
    • When Puerto Rico is included in the selections in the State list, then national rates are not shown.
  • What rates are available for Puerto Rico residents?
    • When rates are requested for Puerto Rico, the query can group results by filter, limit or restrict only Year.
    • Population denominator data are not included in OTIS by age, sex, or race / ethnicity.


Completion of Therapy Within One Year (COT) - percentage measure

Completion of Therapy Within One Year data are available both as a percentage measure and as a categorical variable. The Completion of Therapy Within One Year percentage measure is a column reported in the output for your data query, when you check the box on the Request form for this measure.

Completion of Therapy Within One Year (COT) indicates if the patient completed TB therapy in less than or equal to 366 days of initiating therapy, for patients with "uncomplicated" TB.

Completion of Therapy Within One Year (COT) in OTIS refers to completion of anti-TB drug therapy for an "uncomplicated" patient within 366 days of initiating therapy. COT is typically shown as a percentage or proportion of TB cases that complete therapy within one year (less than or equal to 366 days) and have met several criteria (see detailed criteria in next paragraph). In order to determine whether a case is "uncomplicated," TB cases are stratified by the indicated length of therapy, based on American Thoracic Society/CDC treatment guidelines in effect during the period covered, and the patients initial drug susceptibility test results, age, and site of disease. The adequacy of the treatment regimen (e.g., the sufficiency of the duration of therapy, the appropriateness of the prescribed TB drugs) are not part of the calculation of COT. Acquired drug resistance during therapy with the need for a longer duration of therapy is also not considered.

The determination of the indicated length of therapy for 1 year or less is based on a number of factors. Patients with an initial M. tuberculosis isolate resistant to rifampin, patients with meningeal disease and pediatric patients (less than 15 years old) with miliary disease or a positive blood culture or a positive nucleic acid amplification (NAA) test from a blood specimen require therapy for greater than 366 days and are therefore not included in the calculations of COT appearing on OTIS. Patients with bone or skeletal system disease as well as patients with disease of the central nervous system may also require therapy for greater than 366 days. For all other patients, including those with culture-negative disease, those with an unknown culture status, and those with culture-positive disease, but unknown initial drug susceptibility test results, were included in the calculation of COT for those with 1 year or less of therapy indicated.

The number of cases (i.e., denominator) used to calculate the percentage includes patients meeting the following criteria: 1) had an indicated length of therapy of 1 year or less, 2) were alive at diagnosis and prescribed an initial regimen of one or more drugs, and 3) did not die or move out of the U. S. within one year of initiating therapy. The percentage of COT was calculated by dividing the number of patients reported as having completed therapy in 1 year or less among those eligible by the total number of cases in the denominator. The number of patients included in the calculation is reported in the Completion of Therapy Within One Year categorical variable.

Check the box on the Request form to show Completion of Therapy Within One Year (COT) in your results.

How?    See How do I change a "Check Box?" for more information.

Notes:

  • Due to treatment-related reporting delays, Completion of Therapy Within One Year (COT) data and Directly Observed Therapy (DOT) data are reported from 1993 through two (2) years preceding the last year of data included in the dataset. States have up to two years to report these types of data, thus the case evidence lags 2 years behind the current report year. For example, the OTIS 2023 dataset reports Completion of Therapy Within One Year for the years 1993-2021.
  • "Not Applicable" is displayed for the Completion of Therapy Within One Year (COT) value when the data includes:
    • case reports with an initial M. tuberculosis isolate resistant to rifampin;
    • patients with meningeal disease;
    • pediatric patients (less than 15 years old) with miliary disease;
    • pediatric patients (less than 15 years old) with a positive blood culture or a positive nucleic acid amplification (NAA) test from a blood specimen;
    • patients with bone or skeletal system disease;
    • patients with disease of the central nervous system;
    • patients that were not alive at diagnosis;
    • patients that died or moved out of the U. S. within one year of initiating therapy;
    • case reports within the 2-year period preceding the "vintage" year, meaning the final year included in the data set, also known as the current reporting year.
  • The criteria for the COT calculation changed with OTIS 2006 and later years: previous data releases included patients over age 15 with meningeal disease and pediatric patients with positive blood cultures and excluded pediatric patients with bone or joint disease.
  • OTIS displays Completion of Therapy Within One Year (COT) data as a percentage measure and as a categorical variable. In the previous annual data sets for years before OTIS 2005, Completion of Therapy Within One Year (COT) is displayed as a percentage measure only, and not as a categorical variable.


Drug Susceptibility Testing

There are two measures that show the percentage of case reports that indicate that the patient was tested for drug susceptibility:

  1. Percentage Tested for Susceptibility to Isoniazid (INH): percentage of cases with initial drug susceptibility testing done reporting test results
  2. Percentage Tested for Susceptibility to Isoniazid (INH) and Rifampin (RIF): percentage of cases with initial drug susceptibility testing done reporting test results
There are also two variables that show whether the case report indicates if the patient was tested for drug susceptibility:
  1. Tested for Isoniazid Susceptibility - No, Yes, Not Applicable
  2. Tested for Isoniazid & Rifampin Susceptibility - No, Yes, Not Applicable

Note:  the drug susceptibility testing data are available only for OTIS 2005 data and later.

Starting with OTIS vintage 2023, molecular drug susceptibility testing methods was used to calculate MDR in addition to growth-based methods.

Drug Susceptibility Testing for Isoniazid (INH)

Drug Susceptibility Testing for Isoniazid (INH) data are available both as a measure and as a Disease Criteria variable.

Measure of the percentage of cases with drug susceptibility testing:

"Percentage tested for drug susceptibility to Isoniazid (INH)" is a column reported in the output for your data query, when you check the box on the Request form for this measure. This measure reports the percentage of cases with initial drug susceptibility testing done with test results for Isoniazid susceptibility.

Check the box on the Request form to show Percentage Tested for Susceptibility to Isoniazid (INH) in your results.

How?    See How do I change a "Check Box?" for more information.

Notes:

  • The measure indicates the percentage of cases where drug susceptibility testing results were included in the case report (susceptible or resistant) to at least Isoniazid (INH).
  • The percentage is calculated from the ratio of cases with initial drug susceptibility testing done with drug susceptibility testing results for isoniazid divided by all cases with initial drug susceptibility testing done:

    Number of cases with initial drug susceptibility testing done with testing results for isoniazid / Number of cases with initial drug susceptibility testing done
  • The numerator includes all cases with initial drug susceptibility testing done with reported test results that meet the query criteria. The denominator includes all counted cases with initial drug susceptibility testing done meeting the query criteria.
  • The drug susceptibility testing data are available only for OTIS 2005 data and later years.


Drug Susceptibility Testing for Isoniazid (INH) and Rifampin (RIF)

Drug Susceptibility Testing for Isoniazid (INH) and Rifampin (RIF) data are available both as a measure and as a Disease Criteria variable.

Measure of the percentage of cases with drug susceptibility testing:

"Percentage Tested for Susceptibility to Isoniazid (INH) and Rifampin (RIF)" is a column reported in the output for your data query, when you check the box on the Request form for this measure. This measure reports the percentage of cases with initial drug susceptibility testing done with test results for both Isoniazid and Rifampin susceptibility.

Check the box on the Request form to show Percentage Tested for Susceptibility to Isoniazid & Rifampin in your results.

How?    See How do I change a "Check Box?" for more information.

Notes:

  • The measure indicates the percentage of cases where drug susceptibility testing results were included in the case report (susceptible or resistant) to both Isoniazid (INH) and Rifampin (RIF).
  • The percentage is calculated from the ratio of cases with initial drug susceptibility testing done with drug susceptibility testing results for isoniazid and rifampin divided by all cases with initial drug susceptibility testing done:

    Number of cases with initial drug susceptibility testing done with results for isoniazid and rifampin / Number of cases with initial drug susceptibility testing done
  • The numerator includes all cases with initial drug susceptibility testing done with reported test results that meet the query criteria. The denominator includes all counted, cases with initial drug susceptibility testing done meeting the query criteria.
  • The drug susceptibility testing data are available only for OTIS 2005 data and later years.

Step 2. Select location and years:

Location

Pick any combination of locations desired, from either the State or the MSA lists, but not both. Be sure the button for State or MSA is set to your choice.

How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred location list.

Notes:  

  • State and MSA data are based on the patient's residence at the time of TB diagnosis.
  • Metropolitan Statistical Area (MSA) data are not available in OTIS 2022 and later.
  • "The United States" in the State list does not include Puerto Rico. Select everything but "The United States" to use all the states plus Puerto Rico.


State

Select the United States or any combination of individual states. Be sure the radio button above the State list is selected. The values for this data element include all states, the District of Columbia, and Puerto Rico.

How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred location list.

Notes:  

  • State data are based on the patient's residence at the time of TB diagnosis.
  • "The United States" in the State list does not include Puerto Rico. Select everything but "The United States" to use all the states plus Puerto Rico.
  • Privacy concerns:
    • In order to protect personal privacy, demographic and risk-factor information is limited to the national level for individual years of data. Select either "All Years" or the last 5 years ("2019-2023" in the OTIS 2023 data) if you wish to request specific demographic and/or risk-factor information for a specific location. This rule also applies to queries that "group results by" State or Metropolitan Statistical Area (MSA). Metropolitan Statistical Area (MSA) data are not available in vintage OTIS 2022 and later.
    • All metropolitan data values representing less than 5 cases are marked "Suppressed."
    • All state data values representing less than 5 cases are suppressed, unless the total cases for a state are shown for 1 or more years combined.
    • National data are not suppressed, nor when the total number of cases (no sub-sets) for a state is shown, such as the single cases with initial drug susceptibility testing done in Wyoming in 1999.
    • Note that for data released prior to October 31, 2007, for OTIS 2004 and OTIS 2003, values representing cases counts less than 4 are suppressed for state data unless the total cases in 1 year are shown, and values less than 4 are suppressed for all metropolitan data.
    • All HIV data from the state of Louisiana and Vermont are suppressed when shown at the state or metropolitan (MSA) level. HIV data for Louisiana and Vermont are included at the national level.
    • Rates are available for national and state-level data in OTIS 1993-2005 and later releases. Previous releases OTIS 2004 and OTIS 2003 only provided rates for national data.

The table below shows the Federal Information Processing Standard (FIPS) code value for each state and the state's name, as specified for data export.

FIPS Code State Name
01 Alabama
02 Alaska
04 Arizona
05 Arkansas
06 California
08 Colorado
09 Connecticut
10 Delaware
11 District of Columbia
12 Florida
13 Georgia
15 Hawaii
16 Idaho
17 Illinois
18 Indiana
19 Iowa
20 Kansas
21 Kentucky
22 Louisiana
23 Maine
24 Maryland
25 Massachusetts
26 Michigan
27 Minnesota
28 Mississippi
29 Missouri
30 Montana
31 Nebraska
32 Nevada
33 New Hampshire
34 New Jersey
35 New Mexico
36 New York
37 North Carolina
38 North Dakota
39 Ohio
40 Oklahoma
41 Oregon
42 Pennsylvania
44 Rhode Island
45 South Carolina
46 South Dakota
47 Tennessee
48 Texas
49 Utah
50 Vermont
51 Virginia
53 Washington
54 West Virginia
55 Wisconsin
56 Wyoming
72 Puerto Rico


Metropolitan Statistical Area (MSA)

Note that MSA data are not available in OTIS Vintages 2022-2023.

Select the United States or any combination of individual MSAs. Be sure the radio button above the MSA list is highlighted. The values in this data field are MSAs with a population greater than or equal to 500,000 persons for at least one year during the reporting period. (See list below).

How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred location list.

Notes:   

  • Metropolitan statistical areas are defined by the federal Office of Management and Budget (OMB). The MSA definitions apply to all areas except the six New England states; for these states, the New England County Metropolitan Areas (NECMAs) are used. Metropolitan areas are named for a central city in the MSA or NECMA, may include several cities and counties, and may cross state boundaries. Further information about MSAs can be found on the U.S. Census Bureau website at https://www.census.gov, search for "Metropolitan Statistical Area".
  • In order to protect personal privacy:
    • Demographic and risk-factor information is limited to the national individual years of data.
    • Also, all values less than 5 are suppressed, unless shown at the national level, or unless the total cases for the state OR MSA are shown for a period of one or more years of data combined. (OTIS 2003 and OTIS 2004 suppress values representing fewer than 4 cases.)
    • Select either "All Years" or the last 5 years ("2019-2023" in the OTIS 2022 data) if you wish to request specific demographic and/or risk-factor information for a specific State or MSA. This rule also affects data requests when the "group results by" selection is State or MSA, because each location is reported specifically in the results.
  • When the data are exported to a file, MSA has two columns, one for location name and a second column for code value. To see the list of MSA codes and labels for the previous OTIS releases, request data grouped by MSA and export the results.
  • OTIS includes data for MSAs with populations greater than 500,000 persons in the most recent data year. OTIS 2006 and later releases also reflect a change to the standard MSA codes and labels. Consequently, the metropolitan locations included in the data changed, some areas combined with larger areas, some areas are new, and some areas are omitted. This change is represented in the table below.

MSAs with 500,000 or more population

Current Code  Prior CodeMSA Name
10420 0080 Akron, OH
10580 0160 Albany-Schenectady-Troy, NY
10740 0200 Albuquerque, NM
10900 0240 Allentown-Bethlehem-Easton, PA-NJ
* 0440 Ann Arbor, MI
12060 0520 Atlanta-Sandy Springs-Roswell, GA
12260 * Augusta-Richmond County, GA-SC
12420 0640 Austin-Round Rock, TX
12540 0680 Bakersfield, CA
12580 0720 Baltimore-Columbia-Towson, MD
12940 0760 Baton Rouge, LA
* 0875 Bergen-Passaic, NJ
13820 1000 Birmingham-Hoover, AL
14260 * Boise City, ID
14460 1123 Boston-Cambridge-Newton, MA-NH
14860 * Bridgeport-Stamford-Norwalk, CT
15380 1280 Buffalo-Cheektowaga-Niagara Falls, NY
15980 2700 Cape Coral-Fort Myers, FL
16700 1440 Charleston-North Charleston, SC
16740 1520 Charlotte-Concord-Gastonia, NC-SC
16860 * Chattanooga, TN-GA †
16980 1600 Chicago-Naperville-Elgin, IL-IN-WI
17140 1640 Cincinnati, OH-KY-IN
17460 1680 Cleveland-Elyria, OH
17820 1720 Colorado Springs, CO
17900 1760 Columbia, SC
18140 1840 Columbus, OH
19100 * Dallas-Fort Worth-Arlington, TX
19430 19380, 2000 Dayton-Kettering, OH
* 2020 Daytona Beach, FL
19660 * Deltona-Daytona Beach-Ormond Beach, FL †,§
19740 2080 Denver-Aurora-Lakewood, CO
19780 * Des Moines-West Des Moines, IA
19820 2160 Detroit-Warren-Dearborn, MI
20500 * Durham-Chapel Hill, NC ¶
21340 2320 El Paso, TX
* 2760 Fort Wayne, IN
22180 * Fayetteville, NC §§§
22220 * Fayetteville-Springdale-Rogers, AR-MO ***
23420 2840 Fresno, CA
* 2960 Gary, IN
24340 3000 Grand Rapids-Wyoming, MI
24660 3120 Greensboro-High Point, NC
24860 3160 Greenville-Anderson-Maudlin, SC
25420 3240 Harrisburg-Carlisle, PA
25540 3283 Hartford-West Hartford-East Hartford, CT
* 26180, 3320 Honolulu, HI ††
26420 3360 Houston-The Woodlands-Sugar Land, TX
26620 * Huntsville, AL§§§§
26900 3480 Indianapolis-Carmel-Anderson, IN
27140 * Jackson, MS
27260 3600 Jacksonville, FL
* 3640 Jersey City, NJ
28140 3760 Kansas City, MO-KS
28940 3840 Knoxville, TN
29460 3980 Lakeland-Winter Haven, FL
29540 * Lancaster PA ¶ **
29620 * Lansing-East Lansing, MI §§§
29820 4120 Las Vegas-Henderson-Paradise, NV
* 4280 Lexington, KY
30460 * Lexington-Fayette, KY †††
30780 4400 Little Rock-North Little Rock-Conway, AR
31080 * Los Angeles-Long Beach-Anaheim, CA ¶¶
* 31100, 4480 Los Angeles-Long Beach-Santa Ana, CA ††
31140 4520 Louisville/Jefferson County, KY-IN
31540 * Madison, WI
32580 4880 McAllen-Edinburg-Mission, TX
32820 4920 Memphis, TN-MS-AR
33100 5000, 2680 Miami-Fort Lauderdale-West Palm Beach, FL
* 5015 Middlesex, NJ
33340 5080 Milwaukee-Waukesha-West Allis, WI
33460 5120 Minneapolis-St. Paul-Bloomington, MN-WI
* 5160 Mobile, AL
33700 * Modesto, CA
* 5190 Monmouth-Ocean City, NJ
34820 * Myrtle Beach-Conway-North Myrtle Beach, SC-NC ††††
34980 5360 Nashville-Davidson--Murfreesboro--Franklin, TN
* 5380 Nassau-Suffolk, NY
35300 5483 New Haven-Milford, CT
35380 5560 New Orleans-Metairie, LA
35620 5600 New York-Newark-Jersey-City, NY-NJ-PA
* 5640 Newark, NJ
35840 * Northport-Sarasota-Bradenton, FL ¶¶
36260 * Ogden-Clearfield, UT **, †
36420 5880 Oklahoma City, OK
36540 5920 Omaha-Council Bluffs, NE-IA
* 5945 Orange County, CA
36740 5960 Orlando-Kissimmee-Sanford, FL
37100 8735 Oxnard-Thousand Oaks-Ventura, CA
37340 4900 Palm Bay-Melbourne-Titusville, FL
37860 * Pensacola-Ferry Pass-Brent, FL ****
37980 6160, 9160   Philadelphia-Camden-Wilmington,
PA-NJ-DE-MD
38060 6200 Phoenix-Mesa-Scottsdale, AZ
38300 6280 Pittsburgh, PA
38860 * Portland-South Portland, ME
38900 6440 Portland-Vancouver-Hillsboro, OR-WA
38940 * Port St. Lucie, FL §§§§
39100 * Poughkeepsie-Newburgh-Middletown, NY ††
39300 6483 Providence-Warwick, RI-MA
39340 * Provo-Orem, UT **
39580 6640 Raleigh, NC
40060 6760 Richmond, VA
40140 6780 Riverside-San Bernardino-Ontario, CA
40380 6840 Rochester, NY
40900 6920 Sacramento--Roseville--Arden-Arcade, CA
41180 7040 St. Louis, MO-IL
41620 7160 Salt Lake City, UT
41700 7240 San Antonio-New Braunfels, TX
41740 7320 San Diego-Carlsbad, CA
41860 7360, 5775 San Francisco-Oakland-Hayward, CA
41940 7400 San Jose-Sunnyvale-Santa Clara, CA
41980 7440 San Juan-Carolina-Caguas, PR
* 42220 Santa Rosa, CA ¶¶¶
* 42260, 7510 Sarasota-Bradenton-Venice, FL ††
42540 7560 Scranton--Wilkes-Barre--Hazelton, PA
42660 7600, 8200 Seattle-Tacoma-Bellevue, WA
44060 * Spokane-Spokane Valley, WA §§
44140 8003 Springfield, MA
44700 8120 Stockton-Lodi, CA
45060 8160 Syracuse, NY
45300 8280 Tampa-St. Petersburg-Clearwater, FL
45780 8400 Toledo, OH
46060 8520 Tucson, AZ
46140 8560 Tulsa, OK
46520 * Urban Honolulu, HI ¶¶
* 8720 Vallejo, CA
47260 5720 Virginia Beach-Norfolk-Newport News, VA-NC
47900 8840 Washington-Arlington-Alexandria, DC-VA-MD-WV
* 8960 West Palm Beach, FL
48620 9040 Wichita, KS
49180 * Winston-Salem, NC §§
49340 * Worchester, MA-CT
49660 9320 Youngstown-Warren-Boardman, OH-PA **
99998 * Other areas combined in Puerto Rico §
99999 * Other areas combined in Unites States

Footnotes:

* Indicates code not included in the data.

† Data reporting for the named MSA location begins in 2007 for the 1993-2012 data set and later OTIS releases: Chattanooga, TN-GA; Deltona-Daytona Beach-Ormond Beach, FL; Ogden-Clearfield, UT. Cases in this location are recoded to "other MSA" or reported under different MSA label for years 1993-2006 in OTIS 2012 and preceding releases.

§ Data are not reported for the named MSA location in the OTIS 2009, 2010 and 2012 releases; the cases in the location are recoded to "Other MSA" or reported under a different MSA label in preceding OTIS releases: Deltona-Daytona Beach-Ormond Beach, FL.

¶ Data reporting for the named MSA location occurs in the 1993-2009 data set and later data sets; the cases in the location are recoded to "Other MSA" or reported under a different MSA label in preceding OTIS releases: Durham-Chapel Hill, NC; Lancaster PA.

** These areas did not report any cases for the indicated years: Lancaster, PA in 2007; Ogden-Clearfield, UT in 1997; Provo-Orem, UT in 2010; Youngstown-Warren-Boardman, OH-PA in 2013.

†† Data are not reported for the named MSA location code in the 1993-2012 data set and later years: Honolulu, HI; Los Angeles-Long Beach-Santa Ana, CA; Sarasota-Bradenton-Venice, FL; Poughkeepsie-Newburgh-Middletown, NY. Cases for this location are recoded to "Other MSA." Data are reported for this location in preceding OTIS releases.

¶¶ Data reporting for the named MSA location occurs only in the 1993-2012 data set and later years: Los Angeles-Long Beach-Anaheim, CA; Northport-Sarasota-Bradenton, FL; Urban Honolulu, HI. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or another MSA label.

§§ Data reporting for the named MSA location occurs only in the 1993-2013 data set and later years: Spokane-Spokane Valley, WA; Winston-Salem, NC. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

*** Data reporting for the named MSA location occurs only in the 1993-2014 data set and later years: Fayetteville-Springdale-Rogers, AR-MO. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

††† Data reporting for the named MSA location occurs only in the 1993-2015 data set and later years: Lexington-Fayette, KY. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

§§§ Data reporting for the named MSA location occurs only in the 1993-2018 data set and later years: Fayetteville, NC; Lansing-East Lansing, MI. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

¶¶¶ Data reporting for the named MSA location occurs only in OTIS 2015, OTIS 2016, and OTIS 2017: Santa Rosa, CA. In other releases of OTIS, cases in this location are recoded to "Other MSA" or another MSA label.

**** Data reporting for the named MSA location occurs in OTIS 2019 and later years: Pensacola-Ferry Pass-Brent, FL. In other releases of OTIS, cases in this location are recoded to "Other MSA" or another MSA label.

†††† Data reporting for the named MSA location occurs in the OTIS 2020 and later years: Myrtle Beach-Conway-North Myrtle Beach, SC-NC. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

§§§§ Data reporting for the named MSA locations occurs only in the 1993-2021 data set: Huntsville Alabama, Port St. Lucie, Florida. In prior releases of OTIS, cases in this location are recoded to "Other MSA" or appear under another MSA label.

The OTIS 2021 and OTIS 2020 data sets report MSA labels from the MSA list released in March 2020 by the Office of Management and Budget (OMB).


Year

Select only "All Years," or select only the last 5 years ("2019-2023" in the OTIS 2023 data) or pick any combination of individual years.
How?   See How do I select items from the list box?.

Notes:   

  • The year shown indicates the year when the case was verified and submitted to the CDC as part of the official case count.
  • In order to protect personal privacy, demographic and risk-factor information is limited to the national level for individual years of data.
  • Select either "All Years" or the last 5 years ("2019-2023" in the OTIS 2023 data) if you wish to request specific demographic and/or risk-factor information for a specific State or MSA. This rule also affects data requests when the selection for "group results by" is State or MSA, because the results report each specific location.
  • The value for the last 5 years combined is displayed and exported as code value:
    Code Value Data Set
    "2019-2023" OTIS 2023
    "2018-2022" OTIS 2022
    "2017-2021" OTIS 2021
    "2016-2020" OTIS 2020
    "2015-2019" OTIS 2019
    "2014-2018" OTIS 2018
    "2013-2017" OTIS 2017
    "2012-2016" OTIS 2016
    "2011-2015" OTIS 2015
    "2010-2014" OTIS 2014
    "2009-2013" OTIS 2013
    "2008-2012" OTIS 2012
    "2006-2010" OTIS 2010
    "2005-2009" OTIS 2009
    "2004-2008" OTIS 2008
    "2003-2007" OTIS 2007
    "2002-2006" OTIS 2006
    "2001-2005" OTIS 2005
    "2000-2004" OTIS 2004
    "1999-2003" OTIS 2003

Step 3. Select demographics:
Limit your data for any of the following data elements:
  1. Age Groups - 2 sets of age groups are available.
    1. Broad with 7 categories: 0-4 years; 5-14 years; 15-24 years; 25-44 years; 45-64 years; 65+ years; Not Reported
      or
    2. Standard with 12 categories: < 1 year; 1-4 years; 5-14 years; 15-24 years; 25-34 years; 35-44 years; 45-54 years; 55-64 years; 65-74 years; 75-84 years; 85+ years; Not Reported
  2. Sex - Female, Male, Not Reported
  3. Race / Ethnicity - 2 sets of race / ethnicity categories are available:
    1. Bridged Race / Ethnicity with 6 categories: American Indian or Alaska Native, Non-Hispanic; Asian or Pacific Islander, Non-Hispanic; Black or African American, Non-Hispanic; Hispanic or Latino; White, Non-Hispanic; Not Reported;
      or
    2. Single Race / Ethnicity with 9 categories, available in OTIS 2012 and later vintages only: American Indian or Alaska Native, Non-Hispanic; Asian, Non-Hispanic, Black or African American, Non-Hispanic; Hispanic or Latino; Multiple Race, Non-Hispanic; Native Hawaiian or Other Pacific Islander, Non-Hispanic; White, Non-Hispanic; Not Reported; Other
  4. Occupation - not available in OTIS 2022-2023. Three sets of occupation categories are available for prior releases of OTIS:
    1. Historical Occupation in OTIS 2010-2021: Correctional, Health Care, Migratory Agricultural, Other, Multiple, Not Employed, Not Reported, Invalid (historic occupation data for 2009 and later years are reported as invalid)
      or
    2. Revised Occupation in OTIS 2010-2021: Correctional, Health care, Migratory Agricultural, Not Employed, Not Seeking Employment, Other, Retired, Not Reported, Invalid (revised occupation data for years 1993-2008 are reported as invalid).
      or
    3. Occupation available in OTIS 2009 and earlier: Health Care; Correctional; Migratory Agricultural; Other; Multiple; Not Employed; Not Reported; Unavailable (all 2009 Occupation data are coded as "Unavailable" in OTIS 2009 only).
    How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred list.

    Notes on Demographic Limits:   

    • In order to protect personal privacy, demographic and risk-factor information is limited to the national level for individual years of data.
    • If you wish to limit or "group by" (stratify) specific demographic and/or risk-factor information for a specific state or metropolitan area (MSA), then you must select a combination of 5 or more years as the requested time period. You are also not allowed to "group by" Year because a row for each year is shown in the results. This rule also affects data requests when the "group results by" selection is State or MSA, because the results show specific locations.

    Age Groups

    Select either Broad or Standard age groups, and then pick any combination of age groups from one list.

    How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred list.

    Notes:  

    • The Age shown is the age group of the patient at the time of the first case report. Age groups are based on the patient's age in the month and year the patient was reported to the health department as a suspected case.
    • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.

    Broad Age Groups

    Select the round button to show the list of Broad Age Groups, and then pick any combination of age groups from one list.
    How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred list.

    Notes:  
    • The Age shown is the age group of the patient at the time of the first case report. Age groups are based on the patient's age in the month and year the patient was reported to the health department as a suspected case.
    • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
    • The table below shows the Broad Age Groups, with each value's display-label and code-value as specified for data export.

      Display-Label Code-Value
      0-4 years 0-4
      5-14 years 5-14
      15-24 years 15-24
      25-44 years 25-44
      45-64 years 45-64
      65+ years 65+
      Not Reported NR

    Standard Age Groups

    Select the round button to show the list of Standard Age Groups, and then pick any combination of age groups from one list.
    How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred list.

    Notes:  
    • The Age shown is the age group of the patient at the time of the first case report. Age groups are based on the patient's age in the month and year the patient was reported to the health department as a suspected case.
    • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
    • The table below shows the Standard Age Groups, with each value's display-label and code-value as specified for data export.

      Display-Label Code-Value
       < 1 year 1
      1-4 years 1-4
      5-14 years 5-14
      15-24 years 15-24
      25-34 years 25-34
      35-44 years 35-44
      45-54 years 45-54
      55-64 years 55-64
      65-74 years 65-74
      75-84 years 75-84
      85+ years 85+
      Not Reported NR


    Sex

    The Sex variable shows the reported sex at birth of the person. Select "All" or any combination of values from the list.

    How?   See How do I select items from the list box?.

    Notes:  
    • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
    • The table below shows each value's display-label and code-value as specified for data export.

      Display-Label Code-Value
      Female F
      Male M
      Not Reported NR


    Race / Ethnicity

    Pick between two lists of race / ethnicity categories:

    1. Bridged Race / Ethnicity
    2. Single Race / Ethnicity
    How?  
    1. See How do I change a "Radio Button?" to pick your preferred list.
    2. See How do I select items from the list box? to limit data to selected categories in your preferred list.
    Notes:
    • Rates and the population denominators for rate calculations are not available for
      • break-outs by bridged race / ethnicity categories for cases diagnosed in 2023 and later years; or
      • break-outs by single race / ethnicity categories in OTIS 2012 and later OTIS releases.
    • The bridged race / ethnicity categories available in OTIS 2012 and later releases differ from the race / ethnicity categories in previous releases. For more information on the changes, see Bridged Race / Ethnicity.
    • The race / ethnicity categories available in OTIS 2012 and later releases differ from the race / ethnicity categories in previous releases. For more information on the changes, see Single Race / Ethnicity. In OTIS 2018 and later years, this set of race / ethnicity categories introduced in OTIS 2012 is referred to as "single race" categories.


Bridged Race / Ethnicity

Select "All" or any combination of values from the list. Bridged Race / Ethnicity categories are available for archive OTIS 2003 through the current release.

How?   See How do I select items from the list box?.

Notes:  
  • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
  • Bridged Race / Ethnicity values are calculated by combining race and ethnic origin variables into categories to determine the patients self-identified racial and ethnic category. Persons of Hispanic origin can be of any race. All other categories are non-Hispanic, single race.
  • The "Asian or Pacific Islander" category in the Bridged Race / Ethnicity list contains cases among persons who self-reported race as Asian only or Native Hawaiian or Other Pacific Islander only.
  • TB cases of multiple race consist of less than 1% of all cases and are categorized as "Not Reported" in the Bridged Race / Ethnicity categories.
  • Note that the data by Bridged Race / Ethnicity may not be comparable with data in the new Race / Ethnicity categories available in OTIS 2012 and later releases, particularly for persons in these categories: Asian, Native Hawaiian, Pacific Islander, Multiple Race and Not Reported. The change in categories affects less than 1 percent of the population of TB cases for years 1993-2023.
  • The table below shows each Bridged Race / Ethnicity value's display-label and code-value as specified for data export. The code values are compliant with Public Health Information Network (PHIN) standards when applicable.

    Bridged Race / Ethnicity
    Display-Label Code-Value
    American Indian or Alaska Native, Non-Hispanic 1002-5
    Asian or Pacific Islander, Non-Hispanic A-PI *
    Black or African American, Non-Hispanic 2054-5
    Hispanic or Latino 2135-2
    White, Non-Hispanic 2106-3
    Not Reported NR
     *  Before the December 2008 release of OTIS 2007 data, the "Asian or Pacific Islander" code value was "2000-4" from the PHIN CDC Race Ethnicity code set. However, the "2000-4" value and the "Asian or Pacific Islander" race category are no longer supported in the current release of the CDC Race Ethnicity code set.


Single Race / Ethnicity

Select "All" or any combination of values from the list. This list of categories is available with the release of the 1993-2012 (OTIS 2012) data and later releases.

How?   See How do I select items from the list box?.

Notes:  
  • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
  • Race / Ethnicity values are calculated by combining race and ethnic origin variables into categories to determine the patients self-identified racial and ethnic category. Persons of Hispanic origin can be of any race. All other categories are non-Hispanic, single or multiple race.
  • Note that the data by the previous Race / Ethnicity categories may not be comparable with data in the new Race / Ethnicity categories available in OTIS 2012 and later releases, particularly for persons in these categories: Asian, Native Hawaiian, Pacific Islander, Multiple Race and Not Reported. The change in categories affects less than 1 percent of the population of TB cases for years 1993-2023.
  • In OTIS 2018 and later years, this set of race / ethnicity categories introduced in OTIS 2012 is referred to as "single race" categories.
  • The table below shows each Race / Ethnicity value's display-label and code-value as specified for data export. The code values are compliant with Public Health Information Network (PHIN) standards when applicable.

    Race / Ethnicity
    Display-Label Code-Value
    American Indian or Alaska Native, Non-Hispanic 1002-5
    Asian, Non-Hispanic* A
    Black or African American, Non-Hispanic 2054-5
    Hispanic or Latino 2135-2
    Multiple Race, Non-Hispanic* MULT
    Native Hawaiian or Other Pacific Islander, Non-Hispanic* 2076-8
    White, Non-Hispanic 2106-3
    Other OTH
    Not Reported NR
    * Category available in OTIS 2012 and later releases


Occupation: Historical and Revised

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Occupation data are not available OTIS 2022-2023.
  • OTIS 2010-2021 reports Occupation in two lists.
    1. "Historical Occupation" in years 1993-2008 indicates the occupations of the patient within the 24 months prior to diagnosis.
    2. "Revised Occupation" in years 2010-2021 indicates primary occupation within the 12 months prior to diagnosis.
  • Occupation reporting changed in year 2009. Thus, there are 3 classifications used to report occupation information in OTIS. OTIS 2010 has two fields, "Revised Occupation" categories for cases diagnosed in 2009 and later years, and the obsolete "Historical Occupation" categories for cases diagnosed in 1993-2008. The preceding releases, archive OTIS 2003 through archive OTIS 2009, have a single "Occupation" field, for cases diagnosed in these years. Note that each of these 3 fields has distinctly different code values, do not combine these data.
    • For OTIS 2010 and all later releases:
      • The "Revised Occupation" variable reflects occupation responses in use starting in 2009. The occupation variable criteria changed after 2009 so trending with the original occupation variable, "Historical Occupation," is not possible. Revised Occupation data for years before 2009 are coded as "Invalid."
      • With the release of OTIS 2012 in April 2014, the cases previously categorized as "Not Applicable" are now categorized as "Not Reported" in the "Revised Occupation" field. This change in category label affects the archive OTIS 2010 data.
      • The "Historical Occupation" variable reflects occupation responses for data from 1993-2008. This variable is obsolete after 2008. Historical Occupation data for years after 2008 are coded as "Invalid."
    • For OTIS 2009:
      • All occupation data reported for cases diagnosed in 2009 are categorized as "unavailable" in OTIS 2009. The "unavailable" category applies to 2009 data only, data for preceding years are not in the "unavailable" group. Please be aware of this change when comparing occupation data for multiple years.
  • See Demographic Limits above for more information about how other requested criteria affects the ability to show specific demographic data values.
  • The table below shows each Occupation value's display-label and code-value as specified for data export.

    Revised Occupation in OTIS for years 2010 and later:
    Display-Label Code-Value
    Correctional 1
    Health Care 2
    Migratory Agricultural 3
    Not Employed 4
    Not Seeking Employment 5
    Other 6
    Retired 7
    Not Reported NR
    Invalid * (years 1993-2008 in OTIS 2010 and later) IN
    * Invalid data in the Revised Occupation field are all responses for cases in years before 2009.
    Historical Occupation in OTIS for years 1993-2008.
    Display-Label Code-Value
    Health Care 1
    Correctional 2
    Migratory Agricultural 3
    Other 4
    Multiple 5
    Not Employed 0
    Not Reported NR
    Invalid * (years 2009+ in OTIS 2010 and later) IN
    * Invalid data in the Historical Occupation field are all cases in 2008 and later years, in OTIS 2010 and later releases.
    Occupation in OTIS 2009:
    Display-Label Code-Value
    Health Care 1
    Correctional 2
    Migratory Agricultural 3
    Other 4
    Multiple 5
    Not Employed 0
    Not Reported NR
    Other OTH
    Unavailable * (year 2009 in OTIS 2009 only) UN
    * Unavailable data in the Occupation field are all cases in year 2009 in the OTIS 2009 release only.


Step 4. Select Risk Factors:
Limit your data for any of the following data elements:
  1. Origin of Birth - U.S. Born, Non-U.S.–born, Not Reported
  2. Years in U.S. - Under 1 year, 1-4 years, 5-9 years, 10-14 years, 15-19 years, 20-24 years, 25-29 years, 30-34 years, 35-39 years, >=40 years, Unknown, Not Reported
  3. HIV Status - Positive, Negative, Indeterminate, Not Reported
  4. Homeless in the Past Year? - Yes, No, Not Reported
  5. Residing in a Correctional Facility? - Yes, No, Not Reported
  6. Residing in a Long Term Care Facility? - Yes, No, Not Reported
  7. Place of Residence at Diagnosis? - Correctional Facility, Long Term Care Facility, Not in a Facility, Not Reported
  8. Alcohol Use - Yes, No, Not Reported
  9. Drug Use, Injecting - Yes, No, Not Reported
  10. Drug Use, Non-injecting - Yes, No, Not Reported
  11. Diabetes - Yes, No, Not Reported (Diabetes data available in OTIS 2022)
  12. Smoker Status - Current Smoker Everday, Current Smoker Somedays, Former, Never,Current Smoker Unknown, Not Reported (Smoker Status data available in OTIS 2023)
How?   See How do I select items from the list box? and also see How do I change a "Radio Button?" to pick your preferred list.

Notes on Risk Factor Limits:   
  • In order to protect personal privacy, demographic and risk-factor information is limited to the national level for individual years of data.
  • If you wish to limit or "group by" (stratify) specific demographic and/or risk-factor information for a specific state or metropolitan area (MSA), then you must select a combination of 5 or more years as the requested time period. You are also not allowed to "group by" Year because a row for each year is shown in the results. This rule also affects data requests when the "group results by" selection is State or MSA.


Origin of Birth

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • "Origin of Birth" is defined as follows:  Persons born in the United States, certain U.S. territories, or elsewhere to at least one U.S. citizen parent are categorized as U.S.-born. All other persons are categorized as non-U.S.–born.
  • Exceptions include persons born overseas to U.S. citizens, such as patients born on military bases.
  • The table below shows each "Origin of Birth" value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    U.S. Born 1
    Non-U.S.–born 2
    Not Reported NR


Years in U.S.

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • For cases in persons born outside the United States, this variable shows the number of years since arrival in the U.S.
  • Patients born in the U.S. are not applicable for inclusion in this data element.
    • Thus, the data results may show "Not Applicable" values when the request criteria include data for patients born in the United States.
    • Totals and percentages shown for this data element do not include patients born in the United States, and thus may differ when compared to other data elements where U.S. born cases are included.
  • The table below shows each "Years in U.S." value's display-label and code-value as specified for data export. This list is for OTIS 2023 and later

    Display-Label Code-Value
    < 1 year 1
    1-4 years 2
    5-9 years 3
    9-14 years 4
    15-19 years 5
    20-24 years 6
    25-29 years 7
    30-34 years 8
    35-39 years 9
    ≥ 40 years 10
    Not Reported NR
    Not Applicable NA

  • The table below shows each "Years in U.S." value's display-label and code-value as specified for data export. This list is for vintages prior to 2023

    Display-Label Code-Value
    < 1 year 1
    1-4 years 1-4
    5-14 years 5-14
    15+ years 15+
    Not Reported NR
    Not Applicable NA


HIV Status

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The patient's HIV status is based on published definitions. (Centers for Disease Control and Prevention. Interpretation and use of the Western Blot Assay for serodiagnosis of human immunodeficiency virus type 1 infections. MMWR 1989;38 (No. S-7): 1-7.)
  • Status is considered positive if the patient is tested for HIV and the lab result is interpreted as positive based on published criteria, if the patient has a documented history of previous positive HIV test or diagnosis of HIV infection, or this patient gives a history of a previous positive HIV test.
  • For OTIS releases prior to the 1993-2009 data set, the "Not Reported" status includes indeterminate; refused test; test not offered; test done, results unknown; and missing values. Beginning with the OTIS 1993-2009 data set, "Indeterminate" status is a separate category from "Not Reported" for diagnoses in all years.
  • The information on HIV status for TB cases is incomplete and data should be interpreted with caution. There are a number of reasons for incomplete reporting of HIV test results to the national TB surveillance system including:
    1. concerns about confidentiality of data, which may limit the exchange of data between TB and HIV programs;
    2. laws and regulations in certain states and local jurisdictions that have been interpreted as prohibiting the HIV program from sharing the HIV status of TB patients or from reporting patients with TB and AIDS to the TB program;
    3. the voluntary nature of HIV testing, which some TB patients may decline or for those that are tested, may not choose to share the results with their health department; and
    4. reluctance by health care providers to report HIV test results to the TB surveillance program staff.
  • As a result, these data may not be representative of all TB patients with HIV infection. When analyzing HIV status of TB cases, keep in mind the following limitations:
    • California began reporting HIV test results to CDC in 2011.
    • California did not report HIV test results to CDC for TB cases for years 2005 - 2010. For years prior to 2005, California reported TB cases which had a co-diagnosis of AIDS, as determined by the presence of an AIDS case report in the state AIDS registry. California performed a TB-AIDS case match on an annual basis after both registries had finalized their case counts for the previous year and sent the data to CDC. All other California TB cases for OTIS during these years have an unknown HIV status.
    • The HIV variable, for years prior to 2011, has a high percentage of missing or unknown data. For example, from 1998 through 2000, national HIV results including California showed over 52% missing or unknown. Excluding California, over 42% were missing or unknown during this time.
    • All HIV data from the state of Louisiana are suppressed when shown at the state or metropolitan (MSA) level. HIV data for Louisiana are included at the national level.
    • Rhode Island did not report HIV test results for years 1993-1997.
    • All HIV data from the state of Vermont are suppressed when shown at the state or metropolitan (MSA) level. HIV test results for Vermont are not included for years 2007 - 2011. HIV data for Vermont are included at the national level for years 1993-2006, and for years 2012 and later.
  • The table below shows each "HIV Status" value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Negative N
    Positive P
    Indeterminate * I
    Not Reported NR
      * OTIS 2009 and later releases only


Homeless in the Past Year?

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • "Homelessness Status" value indicates whether the patient was homeless at any time within the 12 months prior to diagnosis.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each "Homelessness Status" value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Residing in a Correctional Facility?

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient was an inmate of a correctional facility at the time the TB diagnostic evaluation was performed.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Residing in a Long-Term Care Facility?

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient was a resident of a long-term care facility at the time the TB diagnostic evaluation was performed.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Place of Residence at Diagnosis?

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates the patient's place of residence at the time the TB diagnostic evaluation was performed.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each "Residence at Diagnosis" value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Correctional Facility 1
    Long-term Care Facility 2
    Not in a Facility 3
    Not Reported NR


Alcohol Use

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient used alcohol to excess within the 12 months prior to diagnosis.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Drug Use, Injecting

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient used an (illegal) injecting drug within the year prior to diagnosis. Injecting drug use involves use of hypodermic needles and syringes for injection of drugs not prescribed by a physician.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Drug Use, Non-injecting

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient used a non-injecting (illegal) drug within the year prior to diagnosis. Non-injecting drug use involves the use of licensed or prescription drugs or illegal drugs that were not injected and were not prescribed by a physician. See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR

Diabetes

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates whether the patient is diabetic.
  • Diabetes data are available in OTIS 2022 and later. Diabetes data are not reported in earlier OTIS releases. In OTIS Vintages 2022 and Vintage 2023, all Diabetes responses are either "Yes" or "Not Reported,” and all cases diagnosed before 2005 are “Not Reported.” Diabetes reporting will be more complete in future OTIS releases.
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No* N
    Yes Y
    Not Reported NR
    * All responses are either "Yes" or "Not Reported" in OTIS 2022.

Smoker Status

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  
  • Indicates the smoker status of the patient.
  • Smoker status data are available in OTIS 2023. Smoker status data are not reported in earlier OTIS releases. In OTIS 2023, all cases diagnosed before 2023 are “Not Reported.”
  • See Risk Factor Limits above for more information about how other requested criteria affects the ability to show specific risk factor data values.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Current Smoker Everyday 1
    Current Smoker Somedays 2
    Former 3
    Never 4
    Current Smoker Unknown 99
    Not Reported 100


Step 5. Select Disease Criteria:
Limit your data for any of the following data elements:
  1. Disease Site - Pulmonary, Extrapulmonary, Both, Not Reported
  2. Multidrug-Resistant - Yes, No, Not Reported
  3. Previous TB - Yes, No, Not Reported
  4. Verification Criteria - Positive Culture, Positive Nucleic Acid Amplification Test, Positive Smear, Clinical Case Definition, Provider Diagnosis
How?   See How do I select items from the list box?.

Disease Site

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • About Miliary Disease Adjustment: Since 2009, evidence of military disease has been classified only as a pulmonary site of disease. From 1997 to 2008, miliary disease was classified as both an extrapulmonary (outside lungs) and a pulmonary (in lungs) form of TB.
  • In publications prior to 1997, miliary disease was classified as extrapulmonary TB unless pulmonary disease was reported as the major site of TB disease.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Pulmonary 1
    Extrapulmonary 2
    Both 3
    Not Reported NR


Multidrug-Resistant

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • Indicates if patient has an initial M. tuberculosis isolate resistant to at least Isoniazid (INH) and Rifampin (RIF). The drug susceptibility testing variables collected on the RVCT forms are used to calculate whether a patient has MDR TB. Patients must have susceptibility testing completed in order to be part of the population (i.e., denominator) for the MDR-TB calculation. If the patient meets this criterion and has susceptibility results that show resistance to at least the drugs isoniazid and rifampin, he/she is defined as having multidrug-resistant TB. This calculation does not consider resistance to other drugs. Resistance to either isoniazid (INH) or rifampin (RIF) and any other drug, is not defined as MDR TB.
  • For inclusion in the MDR data element, the cases must show initial susceptibility testing results for resistance to both INH and RIF.
  • The data results may show "Not Applicable" values when the patient did not show testing to both INH and RIF in initial susceptibility testing.
  • Totals and percentages shown for this data element do not include patients that did not show testing to both INH and RIF in initial susceptibility testing. Thus, totals and percentages may differ when compared to other data elements where those records are included.
  • For the first time, molecular drug susceptibility testing methods was used to calculate MDR in addition to growth-based methods with vintage 2023.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR
    Not Applicable NA


Previous TB

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • Indicates if this patient has had a previous diagnosis of TB.
  • Previous diagnosis is defined as having had verifiable disease in the past, been discharged (e.g., completed treatment) or lost to supervision for more than 12 consecutive months, and then had verifiable disease again.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    No N
    Yes Y
    Not Reported NR


Verification Criteria

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • The Verification Criteria variable groups cases based on the criteria used to determine which part of the case definition was used to verify cases.
  • The Verification Criteria category Positive Nucleic Acid Amplification Test was added in OTIS 2009, and does not apply to cases diagnosed before 2008.
  • The table below shows each value's display-label and code-value as specified for data export.

    Codes for OTIS 2009 and later releases:
    Display-Label Code-Value
    Positive Culture 1
    Positive Nucleic Acid Amplification Test * 2
    Positive Smear 3
    Clinical Case Definition 4
    Provider Diagnosis 5
     * Added in OTIS 2009, not applicable for cases diagnosed before 2008.


Step 6. Select Therapy Issues:
Limit your data for any of the following data elements:
  1. Receives Directly Observed Therapy? - Directed therapy Only, Self-administered Only, Both, Not Reported, Not Applicable
  2. Vital Status - Alive, Dead, Not Reported
  3. Completion of Therapy Within One Year - No, Yes, Not Applicable
  4. Tested for Isoniazid Susceptibility - Yes, No, Not Applicable
  5. Tested for Isoniazid & Rifampin Susceptibility - Yes, No, Not Applicable
How?   See How do I select items from the list box?.

Receives Directly Observed Therapy?

Beginning in OTIS 2023, known electronic directly observed therapy is merged with conventional in-person directly observed therapy.

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • Indicates whether patient received self-administered or directly observed therapy, as defined as the direct visual observation by a health care provider or other reliable party of the patient's ingestion of medication. (American Thoracic Society. Control of Tuberculosis in the United States. Am Rev Respir Dis 1992;146:1623-1633.)
  • Since Directly Observed Therapy is usually reported after treatment completion, only data for 1993 - 2021 are available in OTIS 2023. Directly Observed Therapy (DOT) data are available until two years before the final year in each OTIS release.
  • The Directly-observed therapy (DOT) status of a patient is reported on the RVCT follow-up report. DOT or supervised therapy involves the direct visual observation by a health care provider or other reliable person of a patient's ingestion of medication. DOT regimens may be administered daily, three times a week, or twice weekly. DOT is currently recommended as the best practice treatment for TB patients by the Centers for Disease Control and Prevention.
  • The criteria for inclusion in the DOT data element are:
    • The patient is alive in the specific year; the case record's "Vital Status" value is "ALIVE". Patients that have died in the specified year are not applicable for inclusion in this data element.
    • The patient is receiving treatment with one or more anti-TB drugs. Cases that do not report an active treatment regimen are not included in the DOT measure.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Self Only 1
    Direct Only 2
    Both 3
    Not Reported NR
    Not Applicable NA


Vital Status

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:  

  • Vital Status indicates whether the patient was alive or dead at the time of diagnosis. Patient is considered dead at diagnosis if deceased at the time the investigation of possible TB was initiated.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Alive 1
    Dead 2
    Not Reported NR


Completion of Therapy Within One Year (less than or equal to 366 days)

Completion of Therapy Within One Year data are available both as a categorical variable (yes, no, not reported, not applicable) and as a percentage measure.

Completion of Therapy Within One Year (COT) indicates if the patient completed TB therapy in less than or equal to 366 days for patients with "uncomplicated" TB.

Those TB cases that complete therapy within 366 days or less and have met several criteria (see detailed criteria in next paragraph) are categorized as "Yes." Those TB cases that did not complete therapy in 366 days or less, and also did not meet the criteria for exclusion are categorized as "No." Those TB cases that meet the criteria for exclusion are categorized as "Not Applicable." The criteria for exclusion include cases reported two years or less before the final reporting year, cases where the patient is not alive, and "complicated" cases.

In order to determine whether a case is "uncomplicated," TB cases are stratified by the indicated length of therapy, based on American Thoracic Society/CDC treatment guidelines 14,15 in effect during the period covered, and the patients initial drug susceptibility test results, age, and site of disease. The adequacy of the treatment regimen (e.g., the sufficiency of the duration of therapy, the appropriateness of the prescribed TB drugs) are not part of the calculation of COT. Acquired drug resistance during therapy with the need for a longer duration of therapy is also not considered.

The determination of the indicated length of therapy for 366 days or less is based on a number of factors. Patients with an initial M. tuberculosis isolate resistant to rifampin, patients with meningeal disease, and pediatric patients (less than 15 years old) with miliary disease or positive blood culture or positive nucleic acid amplification (NAA) test from a blood specimen require therapy for greater than 366 days and are therefore classified as "Not Applicable" for measuring Completion of Therapy Within One Year in OTIS. Patients with bone or skeletal system disease as well as patients with disease of the central nervous system may also require therapy for greater than 366 days. For all other patients, including those with culture-negative disease, those with an unknown culture status, and those with culture-positive disease, but unknown initial drug susceptibility test results, were included in the calculation of COT for those with 1 year or less of therapy indicated.

Select "All" or any combination of values from the list.

How?   See How do I select items from the list box?.

Notes:

  • The cases categorized as "Yes" meet the following criteria:
    1. patients completed therapy and had an indicated length of therapy of 1 year or less,
    2. patients were alive at diagnosis and prescribed an initial regimen of one or more drugs, and
    3. did not meet the criteria described below for the "Not Applicable" category.
  • The cases categorized as "No" meet the following criteria:
    1. patients completed therapy and had an indicated length of therapy of more than 1 year,
    2. patients were alive at diagnosis and prescribed an initial regimen of one or more drugs, and
    3. did not meet the criteria described below for the "Not Applicable" category.
  • The cases categorized as "Not Reported" (unknown) meet the following criteria:
    1. patients completed therapy and had an unknown indicated length of therapy due to missing or incomplete start or stop therapy date,
    2. patients were alive at diagnosis and prescribed an initial regimen of one or more drugs, and
    3. did not meet the criteria described below for the "Not Applicable" category.
  • "Not Applicable" is displayed for the Completion of Therapy Within One Year (COT) value when the data includes:
    • case reports with an initial M. tuberculosis isolate resistant to rifampin;
    • patients with meningeal disease;
    • pediatric patients (less than 15 years old) with miliary disease;
    • pediatric patients (less than 15 years old) with a positive blood culture or a positive nucleic acid amplification (NAA) test from a blood specimen;
    • patients with bone or skeletal system disease;
    • patients with disease of the central nervous system;
    • patients that were not alive at diagnosis;
    • patients that died or moved out of the U. S. within one year of initiating therapy;
    • case reports within the 2-year period preceding the "vintage" year of the data set, meaning the final year included in the data set, also known as the current reporting year.
  • The criteria for the COT calculation have changed several times over the past few OTIS releases to reflect the changing nature of the calculation and to best reflect the cases that can reasonably be expected to complete therapy within one year. With the OTIS 2012 and later, patients who died or move out of the U.S. after one year are included. Patients with bone or skeletal system disease as well as patients with disease of the central nervous system are excluded. Patients with meningeal disease are also excluded. Previous data releases excluded patients under age 15 with meningeal disease or with bone or joint disease, and included pediatric patients with positive blood cultures.
  • For the calculation of the COT percentage measure:
    • Cases that are categorized as "Yes" are included in the numerator.
    • Cases that are categorized as either "Yes," "No" or "Not Reported" (unknown) are included in the denominator.
    • Cases that are categorized as "Not Applicable" are excluded from the calculation.
  • Since Completion of Therapy data is usually reported after treatment completion, Completion of Therapy Within One Year (COT) data and Directly Observed Therapy (DOT) data are reported from 1993 through two (2) years preceding the last year of data included in the dataset. States have up to two years to report these types of data, thus the case evidence lags 2 years behind the current report year. For example, the OTIS 2023 dataset reports Completion of Therapy Within One Year and Directly Observed Therapy (DOT) for the years 1993-2021.
  • OTIS 2005 and later years report Completion of Therapy Within One Year (COT) data as a categorical variable and as a percentage measure. In the previous annual data sets, Completion of Therapy Within One Year (COT) is displayed as a percentage measure only, and not as a categorical variable.
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Yes Y
    No N
    Not Reported NR
    Not Applicable NA



Tested for Isoniazid Susceptibility

Drug Susceptibility Testing for Isoniazid (INH) data are available both as a measure and as a Disease Criteria variable.

Cases with drug susceptibility testing for Isoniazid:

All case reports are categorized to indicate whether drug susceptibility test results for Isoniazid (INH) are reported. The categories are Yes, No and Not Applicable.

Select specific categories or choose to group your data by this variable in the Request form.

How?   See How do I select items from the list box?.

Notes:

  • The "Yes" category shows the number of cases with initial drug susceptibility testing done for isoniazid where drug susceptibility testing results are indicated in the case report (susceptible or resistant).
  • The "No" category shows the number of cases with initial drug susceptibility testing done for isoniazid where drug susceptibility testing results are not included in the case report.
  • The "Not Applicable" category shows the number of cases that are not cases with initial drug susceptibility testing done.
  • For the first time, molecular drug susceptibility testing methods was used to calculate MDR in addition to growth-based methods starting with Vintage 2023
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Yes Y
    No N
    Not Applicable NA


Tested for Isoniazid & Rifampin Susceptibility

Drug susceptibility testing for Isoniazid (INH) and Rifampin (RIF) data are available both as a measure and as a Disease Criteria variable.

Cases with drug susceptibility testing for Isoniazid and Rifampin:

All case reports are categorized to indicate whether drug susceptibility test results for Isoniazid (INH) and Rifampin (RIF) are reported. The categories are Yes, No and Not Applicable.

Select specific categories, or choose to group your data by this variable in the Request form.

How?   See How do I select items from the list box?.

Notes:

  • The "Yes" category shows the number of cases with initial drug susceptibility testing done for isoniazid and rifampin where drug susceptibility testing results are indicated in the case report (susceptible or resistant).
  • The "No" category shows the number of cases with initial drug susceptibility testing done for isoniazid and rifampin where drug susceptibility testing results are not included in the case report.
  • The "Not Applicable" category shows the number of cases that are not cases with initial drug susceptibility testing done.
  • For the first time, molecular drug susceptibility testing methods was used to calculate MDR in addition to growth-based methods starting with Vintage 2023
  • The table below shows each value's display-label and code-value as specified for data export.

    Display-Label Code-Value
    Yes Y
    No N
    Not Applicable NA

Step 7. Other options:
Export Results:    If checked, then query results are exported to a local file. More information on how to import this file into other applications can be found here.
How?   See Check Box.
Show Totals:    If checked, then totals and sub-totals display in the results table.
How?   See Check Box.
Show Zero Values:    If checked, then rows containing zero counts display in the results table. If unchecked, then zero count rows are not displayed.
How?   See Check Box.
Precision:    Choose the precision for the rates calculated with your data. Select the number of digits shown after the decimal point.
Data Access Timeout:    This value specifies the maximum time to wait for the data access for a query to complete. If the data access takes too long to complete, a message will be displayed, and you can increase the timeout or simplify your request. If you can't complete a request using the maximum timeout, contact user support and we will try to run a custom data request for you.

Data Source Information

To learn more about the methods and source of these data please refer to:


Additional Information

Suggested Data Source Citations:    Incidence Data

Online Tuberculosis Information System (OTIS), National Tuberculosis Surveillance System, United States, 1993-2023. U.S. Department of Health and Human Services (US DHHS), Centers for Disease Control and Prevention (CDC), CDC WONDER On-line Database, November 2024. Data for all years updated by July 17, 2024.
Note:  Citations for archive data vary as listed:

Data Set     Data Years     Database Released     Cases Reported By
OTIS 2022     1993-2022     November 2023     July 17, 2023
OTIS 2021     1993-2021     November 2022     July 8, 2022
OTIS 2020     1993-2020     October 2021     June 14, 2021
OTIS 2019     1993-2019     November 2020     June 10, 2020
OTIS 2018     1993-2018     October 2019     June 6, 2019
OTIS 2017     1993-2017     October 2018     June 1, 2018
OTIS 2016     1993-2016     October 2017     June 21, 2017
OTIS 2015     1993-2015     December 2016     June 9, 2016
OTIS 2014     1993-2014     January 2016     June 5, 2015
OTIS 2013     1993-2013     April 2015     June 11, 2014
OTIS 2012     1993-2012     April 2014     June 10, 2013
OTIS 2010     1993-2010     November 2012     July 21, 2011
OTIS 2009     1993-2009     April 2011     July 1, 2010
OTIS 2008     1993-2008     February 2010     May 20, 2009
OTIS 2007     1993-2007     January 2009     April 23, 2008
OTIS 2006     1993-2006     February 2008     July 18, 2007
OTIS 2005     1993-2005     September 2007      
OTIS 2004     1993-2004     March 2006      
OTIS 2003     1993-2003     May 2005      


Population Sources

Population denominators used to calculate United States national and state rates for the years 1993-2020 were obtained from the National Center for Health Statistics (NCHS) bridged-race population counts. See National Center for Health Statistics Population Estimates for more information.

Population estimates for incidence rates are July 1st, 2022 postcensal estimates of the resident population of the United States for July 1, 2020, to July 1, 2022, by year, county, single year of age (range: 0 to 85+ years), bridged-race (American Indian or Alaska Native, Asian or Pacific Islander, Black or African American, White), Hispanic ethnicity (Hispanic or Latino, not Hispanic or Latino), and sex (Female, Male), prepared under a collaborative arrangement with the U.S. Census Bureau and the National Cancer Institute (NCI). The "Vintage 2022" population estimates for years 2020-2022 were released March 2024 by the National Cancer Institute at https://seer.cancer.gov/popdata/. For more information, see https://seer.cancer.gov/popdata/singleages.html.

The current release of OTIS 2023 combines five series of population estimates for US state populations:

  1. 2020 to 2023 (Vintage 2023) postcensal estimates of the July 1 resident population by year, county, age groups, race, sex, and Hispanic origin released by the US Census Bureau on June 27, 2024. The methodology states the 2020-2023 series of estimates are based on the Modified Blended Base produced by the US Census Bureau in lieu of the April 1, 2020 decennial population count. The Modified Blended Base consists of the blend of Vintage 2020 postcensal population estimates for April 1, 2020, the 2020 Demographic Analysis Estimates, and 2020 Census data from the internal Census Edited File (CEF) (see The 2020-2023 Population Estimates Methodology).
  2. Population estimates for incidence rates are July 1st, 2022 postcensal estimates of the resident population of the United States for July 1, 2020, to July 1, 2022, by year, county, single year of age (range: 0 to 85+ years), bridged-race (American Indian or Alaska Native, Asian or Pacific Islander, Black or African American, White), Hispanic ethnicity (Hispanic or Latino, not Hispanic or Latino), and sex (Female, Male), prepared under a collaborative arrangement with the U.S. Census Bureau and the National Cancer Institute (NCI).
  3. The postcensal resident population July 1st estimates for 2010-2020, based on the April 1st, 2010 Census, from the Vintage 2020 bridged-race estimates (release date September 22, 2021). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau. The Census Bureau uses the term "vintage" to describe the final year of data included in the series, the year the series was bottled, so to speak.
  4. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  5. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding releases of OTIS 2022 and 2021 and 2020 combines three series of population estimates for US state populations:
  1. The postcensal resident population July 1st estimates for 2010-2020, based on the April 1st, 2010 Census, from the Vintage 2020 bridged-race estimates (release date September 22, 2021). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau. The Census Bureau uses the term "vintage" to describe the final year of data included in the series, the year the series was bottled, so to speak.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2019 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2019, based on the April 1st, 2010 Census, from the Vintage 2019 bridged-race estimates (release date July 9, 2020). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau. The Census Bureau uses the term "vintage" to describe the final year of data included in the series, the year the series was bottled, so to speak.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2018 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2018, based on the April 1st, 2010 Census, from the Vintage 2018 bridged-race estimates (release date June 25, 2019). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau. The Census Bureau uses the term "vintage" to describe the final year of data included in the series, the year the series was bottled, so to speak.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2017 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2017, based on the April 1st, 2010 Census, from the Vintage 2017 bridged-race estimates (release date June 27, 2018). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau. The Census Bureau uses the term "vintage" to describe the final year of data included in the series, the year the series was bottled, so to speak.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2016 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2016, based on the April 1st, 2010 Census, from the Vintage 2016 bridged-race estimates (release date June 26, 2017). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2015 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2015, based on the April 1st, 2010 Census, from the Vintage 2015 bridged-race estimates (release date June 28, 2016). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2014 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2014, based on the April 1st, 2010 Census, from the Vintage 2014 bridged-race estimates (release date June 30, 2015). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2013 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2013, based on the April 1st, 2010 Census, from the Vintage 2013 bridged-race estimates (release date June 26, 2014). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2012 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for 2010-2012, based on the April 1st, 2010 Census, from the Vintage 2012 bridged-race estimates (release date June 13, 2013). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

The preceding release of OTIS 2010 combines three series of population estimates for US state populations:

  1. The postcensal resident population July 1st estimates for year 2010, based on the April 1st, 2010 Census, from the Vintage 2011 bridged-race estimates (release date July 18, 2012). The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  2. The revised intercensal July 1st population estimates for 2000-2009 (release date October 26, 2012). The 2000-2009 estimates incorporate the bridged-single-race estimates of the April 1, 2000 and April 1, 2010 resident populations. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau.
  3. The revised intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The estimates were prepared under a collaborative arrangement with the National Center for Health Statistics and the U.S. Census Bureau, with support from the National Cancer Institute.

For preceding releases of OTIS 2003 through OTIS 2009, two series were combined for US state populations:

  1. The postcensal resident population July 1st estimates, based on the Census 2000 counts:

    TB Data Set     Population Estimates Series     Series Released
    OTIS 2009     2001 - 2009     July 23, 2010
    OTIS 2008     2001 - 2008     September 2, 2009
    OTIS 2007     2001 - 2007     September 5, 2008
    OTIS 2006     2001 - 2006     August 16, 2007
    OTIS 2005     2001 - 2005     August 16, 2006
    OTIS 2004     2001 - 2004     September 8, 2005
    OTIS 2003     2001 - 2003     September 14, 2004

  2. The intercensal July 1st population estimates for 1990-1999 (release date July 26, 2004). The 1990-1999 estimates were updated to incorporate the bridged-single-race estimates of the April 1, 2000 resident population. The files were prepared under a collaborative arrangement with the U.S. Census Bureau, with support from the National Cancer Institute. See National Center for Health Statistics Population Estimates for more information.
Population denominators used to calculate rates for Puerto Rico were obtained from the following sources for OTIS 2023, and preceding releases since OTIS 2010:
  1. OTIS 2021 - OTIS 2023:
    • Population estimates for Puerto Rico are the 2022 mid-year estimates from the U.S. Census Bureau International Data Base, accessed on May 02, 2024, at https://www.census.gov/data-tools/demo/idb/#/country?YR_ANIM=2022. The choice of population denominators for incidence is based on the availability of population data at the time of publication preparation.
    • "Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico: April 1, 2020 to July 1, 2022," released December 2022 by the US Census Bureau. Accessed at https://www.census.gov/data/tables/time-series/demo/popest/2020s-national-total.html.
    • The 2021 total population estimate of 3,263,584 for Puerto Rico in OTIS 2022 and OTIS 2021 is the July 1, 2021 estimate obtained from the "Annual Estimates of the Resident Population for Selected Age Groups by Sex for Puerto Rico Commonwealth: April 1, 2020 to July 1, 2021 (PRC-EST2021-AGESEX)," released June 2022 by the US Census Bureau. Accessed at https://www.census.gov/data/tables/time-series/demo/popest/2020s-detail-puerto-rico.html from https://www2.census.gov/programs-surveys/popest/tables/2020-2021/puerto-rico/asrh/PRC-EST2021-AGESEX.xlsx.
    • The 2020 total population estimate of 3,285,874 for Puerto Rico in OTIS 2022 and OTIS 2021 is the April 1, 2020 estimate obtained from the "Annual Estimates of the Resident Population for Selected Age Groups by Sex for Puerto Rico Commonwealth: April 1, 2020 to July 1, 2021 (PRC-EST2021-AGESEX)," released June 2022 by the US Census Bureau. Accessed at https://www.census.gov/data/tables/time-series/demo/popest/2020s-detail-puerto-rico.html from https://www2.census.gov/programs-surveys/popest/tables/2020-2021/puerto-rico/asrh/PRC-EST2021-AGESEX.xlsx.
  2. 2010-2020: Vintage 2020: The Puerto Rico population estimates for years 2010-2020 are from the U.S. Census Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico (April 1, 2010 to July 1, 2020) accessed September 24, 2021.
  3. 2010-2019: Vintage 2019: Population figures for Puerto Rico were obtained from the "Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico: April 1, 2010 to July 1, 2019," released December 2019 by the US Census Bureau. Accessed at https://www.census.gov/data/tables/time-series/demo/popest/2010s-national-total.html.
  4. 2010-2018: Vintage 2018: Population figures for Puerto Rico were obtained from the "Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico: April 1, 2010 to July 1, 2018." Accessed June 18, 2019, at https://www.census.gov/data/tables/time-series/demo/popest/2010s-national-total.html.
  5. 2010-2017: Vintage 2017: Population figures for Puerto Rico were obtained from the U.S. Census Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico (April 1, 2010 to July 1, 2017) accessed July 2, 2018, at https://www.census.gov/data/tables/2017/demo/popest/total-puerto-rico-municipios.html.
  6. 2010-2016: Vintage 2016: Population figures for Puerto Rico were obtained from U.S. Census Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico (April 1, 2010 to July 1, 2016) (U.S. Census Bureau web site) accessed July 6, 2017.
  7. 2010-2015: Vintage 2015: Population figures for Puerto Rico were obtained from U.S. Census Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico (April 1, 2010 to July 1, 2015) accessed July 20, 2016, at http://www.census.gov/popest/data/national/totals/2015/index.html.
  8. 2010-2014: Vintage 2014: Puerto Rico Commonwealth Tables of July 1st postcensal estimates (release date December 2014), accessed on January 11, 2015, at http://www.census.gov/popest/data/historical/2010s/vintage_2014/puerto_rico.html.
  9. 2010-2013: Vintage 2013: Puerto Rico Commonwealth Tables of July 1st postcensal estimates (release date December 2013), accessed on March 6, 2015, obtained from http://www.census.gov/popest/data/historical/2010s/vintage_2013/puerto_rico.html.
  10. 2010-2012: Vintage 2012: Puerto Rico Commonwealth Tables of July 1st postcensal estimates (release date December 2012), accessed on February 5, 2014, at http://www.census.gov/popest/data/historical/2010s/vintage_2012/puerto_rico.html.
  11. 2000-2010: Puerto Rico Intercensal Estimates 2000-2010 (release date October 2012), July 1st resident population estimates that incorporate the April 1st, 2000 and April 1st, 2010 Census, accessed on November 1, 2012, at http://www.census.gov/popest/data/intercensal/puerto_rico/pr2010.html. For more information on this series, see https://www.census.gov/data/tables/time-series/demo/popest/intercensal-2000-2010-puerto-rico.html.
  12. 1993-1999: Puerto Rico July 1st resident population estimates for years 1993-1999 were obtained from the U.S. Census Bureau, International Data Base accessed on September 6, 2007 at http://www.census.gov/population/international/.
For previous releases of OTIS through the 2009 release, the populations for Puerto Rico were obtained from these sources:
  1. 2009: Puerto Rico July 1st resident population estimates for year 2009 were obtained from the Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico:   April 1, 2000 to July 1, 2009 [NST-EST2009-01] accessed on April 13, 2011 at http://www.census.gov/popest/states/tables/NST-EST2009-01.xls.
  2. 2008: Puerto Rico July 1st resident population estimates for year 2008 were obtained from the Annual Estimates of the Resident Population for the United States, Regions, States, and Puerto Rico:   April 1, 2000 to July 1, 2008 [NST-EST2008-01] accessed on February 2, 2010 at http://www.census.gov/popest/states/tables/NST-EST2008-01.xls.
  3. 2006-2007: Puerto Rico July 1st resident population estimates for years 2006 and 2007 were obtained from the Annual Estimates of the Population for the United States and States, and for Puerto Rico:   April 1, 2000 - July 1, 2007 (NST-EST2007-01) accessed June 25, 2008 at http://www.census.gov/popest/states/tables/NST-EST2007-01.xls.
  4. 1993-2005: Puerto Rico July 1st resident population estimates for years 1993-2005 were obtained from the U.S. Census Bureau, International Data Base, accessed September 6, 2007 at http://www.census.gov/population/international/.
Rates for Puerto Rico are available only in OTIS 2005 and later. Rates are not available by race, age or gender for Puerto Rico, due to lack of demographic detail in the population data.

Note that the population figures and resulting incidence rates in OTIS may differ slightly from rates in previous publications and reports that used different population sources.

Contact:    For questions about the National Tuberculosis Surveillance System, please contact the program at

E-mail: tbinfo@cdc.gov

Note:   State and local health departments have the most up-to-date and complete data making them the best source for local inquiries; therefore, for further state-specific information, please contact the health department of the state.

Data Release Policies:    Data release policies imposed to protect personal privacy, and to honor the policies of our partners:

Values less than 5:

  • All cell values representing less than 5 cases are suppressed at the metropolitan (MSA) level.
  • Cell values representing less than 5 cases are suppressed at the state level, unless the cell displays the total cases reported by a state for a period of one or more years.
Note that for data released prior to October 31, 2007, for OTIS 2004 and OTIS 2003, values representing cases counts less than or equal to 3 are suppressed for state data unless the total cases in 1 year are shown, and values less than 4 are suppressed for all metropolitan data.

Louisiana HIV data: All HIV data from the state of Louisiana are suppressed when shown at the state or metropolitan (MSA) level. HIV data for Louisiana are included at the national level.

Vermont HIV data: All HIV data from the state of Vermont are suppressed when shown at the state or metropolitan (MSA) level. HIV data for Vermont are included at the national level. (Note that HIV test results for Vermont are not included for years 2007 - 2011.)

Rates: Incidence rates are calculated only for national or state data. Incidence rates are calculated only for national data in the preceding OTIS 2003 and OTIS 2004.

Assurance of Confidentiality:    Public Release Disclosure Statement

The data for OTIS contains information abstracted from the national tuberculosis (TB) case report form called the Report of Verified Case of Tuberculosis (RVCT) (OMB No. 0920-0026). These data have been reported voluntarily to CDC by state and local health departments and are protected under the Assurance of Confidentiality (Sections 306 and 308(d) of the Public Health Service Act, 42 U.S.C. 242k and 242m(d)), which prevents disclosure of any information that could be used to directly or indirectly identify patients. The data on OTIS are being released for public use in accordance with the Assurance of Confidentiality and do not identify patients directly, nor do they contain information that can identify patients indirectly. Any effort to determine the identity of any reported cases, or to use the information for any purpose other than statistical reporting and analysis, is a violation of the Assurance of Confidentiality. Therefore, users will

  • Use the data for statistical reporting and analysis only.
  • Make no attempt to learn the identity of any person or establishment included in these data.
  • Make no disclosure or other use of the identity of any person or establishment discovered inadvertently, and advise the
       Division of Tuberculosis Elimination
       National Center for HIV, Viral Hepatitis, STD, and TB Prevention
       Centers for Disease Control and Prevention
       Atlanta, Georgia 3033
       Phone: 404-639-8120
       Fax: 404-718-8308
       E-mail: TBInfo@cdc.gov
    and the relevant state or public health agency, of such a discovery.
  • Data users should not state or imply interpretations of the data analysis are attributable to the Centers for Disease Control and Prevention unless they are collaborating with CDC personnel on the analysis of the data and have written permission from their CDC collaborators to state or imply attribution to CDC.
  • For more information, see the following policies:

Confidentiality Procedures

In accordance with CDC guidelines, confidentiality procedures were determined through careful examination of data by CDC's Division of Tuberculosis Elimination (DTBE) staff and state TB data providers. Aggregation, the grouping of continuous variables into specific intervals, is the main technique used by DTBE to protect the confidentiality of the national TB surveillance data. OTIS users will have the ability to query demographic and risk factor variables at the state and MSA levels for two different time intervals by year of reporting, "previous 5 years" (2017-2021) or any 5-year aggregate time period, and all years included in data set, since 1993). Cell suppression is applied to count values less than five [5] at the state and the metropolitan (MSA) level. Cell suppression is not applied at the state level when the cell represents values for the total cases reported by a state within a time period of one or more years. (OTIS 2003 and OTIS 2004 suppress cell values representing three (3) or less case counts at the state and MSA levels.) Rates are available at state and national level in OTIS 2005 and later releases. Rates are only available at the national level in OTIS 2004 and prior releases. Demographic and risk factor variables include the following: Sex; Bridged Race/Ethnicity; Race/Ethnicity; Country of Birth; Broad Age Groups; Standard Age Groups; HIV Status; Resident of a Long-term Care Facility; Resident of a Correctional Facility; Homeless; Historical Occupation; Revised Occupation; Injecting Drug Use; Non-injecting Drug Use; Excessive Use of Alcohol. Data for demographic and risk factor variables are not available at the state or MSA levels for individual years. However, OTIS users are able to query single year data for all other variables at all geographic levels.

In addition, data are suppressed in respect to the policies of our partners, for more information, refer to Data Release Policies.

Note:    Errata for the Completion of Therapy Within One Year calculation for OTIS 2003 and OTIS 2004:

On August 29, 2007, the formula for the calculation of Completion of Therapy Within One Year was revised. The algorithm now includes case reports for patients that are 14 years of age in the subset of cases that are measured. Slight discrepancies were noted when comparing the Completion of Therapy Within One Year measures generated by OTIS 2003 and OTIS 2004 to the previously published TB Surveillance Annual Summary reports for the same year. This discrepancy was identified as the omission of the case reports for 14 year old patients. We apologize for this error.

Note that the population figures and resulting incidence rates in OTIS may differ slightly from rates in previous publications and reports that used different population sources. See Population Sources for more information.



This page last reviewed: Thursday, December 05, 2024
This information is provided as technical reference material. Please contact us at cwus@cdc.gov.